Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

(2016) Christophe E. Redon et al.   Aging-US

Molecular mechanisms underlying ochratoxin A-induced genotoxicity: global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression

(2013) Daisuke Hibi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

Double strand break repair functions of histone H2AX

(2013) Ralph Scully et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Ochratoxin A and Mitotic Disruption: Mode of Action Analysis of Renal Tumor Formation by Ochratoxin A

(2012) Angela Mally   TOXICOLOGICAL SCIENCES

BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1

(2011) Lisa Dohrn et al.   BIOCHEMICAL JOURNAL

An Update on Direct Genotoxicity as a Molecular Mechanism of Ochratoxin A Carcinogenicity

(2011) Annie Pfohl-Leszkowicz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Site-Specific In Vivo Mutagenicity in the Kidney of gpt Delta Rats Given a Carcinogenic Dose of Ochratoxin A

(2011) Daisuke Hibi et al.   TOXICOLOGICAL SCIENCES

RAD18 lives a double life: Its implication in DNA double-strand break repair

(2010) Liu Ting et al.   DNA REPAIR

Expression of DNA repair and apoptosis genes in mitochondrial mutant and normal cells following exposure to ionizing radiation

(2010) Rohan Kulkarni et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B-induced deletions in the epidermis of gpt delta transgenic mice

(2010) Kenichi Masumura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity

(2009) Melanie Adler et al.   CARCINOGENESIS

Structures of Covalent Adducts between DNA and Ochratoxin A: A New Factor in Debate about Genotoxicity and Human Risk Assessment

(2009) Peter G. Mantle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The mycotoxin ochratoxin A inhibits DNA topoisomerase II and induces polyploidy in cultured CHO cells

(2009) Simona Cosimi et al.   TOXICOLOGY IN VITRO

Histone H2AX Phosphorylation Independent of ATM after X-irradiation in Mouse Liver and Kidney in situ

(2008) Manabu KOIKE et al.   JOURNAL OF RADIATION RESEARCH

DNA Damage Responses: Mechanisms and Roles in Human Disease: 2007 G.H.A. Clowes Memorial Award Lecture

(2008) M. B. Kastan   MOLECULAR CANCER RESEARCH

Assessment of DNA double-strand breaks and γH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone

(2008) Daniel J. Smart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS