The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis

Valproic Acid Induces the Hyperacetylation of P53, Expression of P53 Target Genes, and Markers of the Intrinsic Apoptotic Pathway in Midorganogenesis Murine Limbs

(2015) France-Hélène Paradis et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

The Type I BMP Receptor ACVR1/ALK2 is Required for Chondrogenesis During Development

(2015) Diana Rigueur et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Teratogenic Activity of HDAC Inhibitors

(2014) Erminio Giavini et al.   CURRENT PHARMACEUTICAL DESIGN

New and emerging HDAC inhibitors for cancer treatment

(2014) Alison C. West et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessment of the developmental toxicity of nanoparticles in anex vivo3D model, the murine limb bud culture system

(2014) Emilia Bigaeva et al.   Nanotoxicology

Class I to III Histone Deacetylases Differentially Regulate Inflammation-Induced Matrix Metalloproteinase 9 Expression in Primary Amnion Cells

(2014) Marin Poljak et al.   Reproductive Sciences

SIRT1 Inhibition Affects Angiogenic Properties of Human MSCs

(2014) Botti Chiara et al.   Biomed Research International

Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube

(2013) Christina Murko et al.   DIFFERENTIATION

Sirt1-deficient mice exhibit an altered cartilage phenotype

(2013) Odile Gabay et al.   JOINT BONE SPINE

Deprenyl Enhances the Teratogenicity of Hydroxyurea in Organogenesis Stage Mouse Embryos

(2013) Ava E. Schlisser et al.   TOXICOLOGICAL SCIENCES

Hydroxyurea Exposure Triggers Tissue-Specific Activation of p38 Mitogen-Activated Protein Kinase Signaling and the DNA Damage Response in Organogenesis-Stage Mouse Embryos

(2013) Serena Banh et al.   TOXICOLOGICAL SCIENCES

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

Hdac-Mediated Control of Endochondral and Intramembranous Ossification

(2012) Jennifer J. Westendorf et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Interplay of Nkx3.2, Sox9 and Pax3 Regulates Chondrogenic Differentiation of Muscle Progenitor Cells

(2012) Dana M. Cairns et al.   PLoS One

Exposure to Valproic Acid Inhibits Chondrogenesis and Osteogenesis in Mid-Organogenesis Mouse Limbs

(2012) France-Hélène Paradis et al.   TOXICOLOGICAL SCIENCES

Generation and characterization of Col10a1-mcherry reporter mice

(2011) Peter Maye et al.   GENESIS

Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development

(2011) Ming Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

VPA-related axial skeletal defects and apoptosis: A proposed event cascade☆

(2009) Francesca Di Renzo et al.   REPRODUCTIVE TOXICOLOGY

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

(2008) Rusty L. Montgomery et al.   JOURNAL OF CLINICAL INVESTIGATION

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY