Article
Chemistry, Inorganic & Nuclear
Fei Fang, Jia-Xin Kang, Cong-Qiao Xu, Jiarui Chang, Jie Zhang, Shujun Li, Xuenian Chen
Summary: The influence of the pincer platform composition and substitution on the reactivity and physical properties of pincer complexes is easily explored experimentally, with subtle effects on the molecular structures and thermodynamic stability. The bond lengths and strengths of M-C-ipso, M-P, and M-X were discussed, along with thermochemical balances for different types of pincer complexes.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Mengfu Dai, Zhimin Sun, Liang-An Chen
Summary: This study reports a catalyst-controlled, tunable, and predictable regiodivergency in transforming internal aliphatic propargyl esters into diverse products, allowing facile access to regioisomers with high regio- and stereoselectivity. This method is important for the structural diversification of bioactive molecules, enabling the rapid assembly of structural analogs of pharmaceutical candidates.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Inorganic & Nuclear
Luis M. Martinez-Prieto, Diego Rio, Eleuterio Alvarez, Pilar Palma, Juan Campora
Summary: The study investigated the reactions of pincer hydroxide complexes with dimethyl carbonate and organic electrophiles, shedding light on the irreversible cleavage of DMC by Ni and Pd hydroxides. The computational DFT models satisfactorily reproduced the kinetic and thermodynamic features of these reactions, explaining the primary cause preventing methanol carboxylation catalysis by Ni or Pd pincers.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Amy L. Speelman, Kazimer L. Skubi, Brandon Q. Mercado, Patrick L. Holland
Summary: Recent experimental evidence indicates that during N-2 reduction, the FeMoco of nitrogenase undergoes structural rearrangement, leading to the generation of coordinatively unsaturated iron sites. New designed ligands have shown the potential flexibility in structural arrangement of metal complexes, mimicking the resting state of nitrogenase.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Jaime Alberto Rosas-Ortiz, J. Roberto Pioquinto-Mendoza, Lucero Gonzalez-Sebastian, Simon Hernandez-Ortega, Marcos Flores-Alamo, David Morales-Morales
Summary: This study reports the synthesis of Ni(II) and Pd(II) coordination complexes containing Schiff's bases derived from condensation reactions. The unexpected C-P bond formation during the synthesis process is proposed to occur through a Kabachnik-Field mechanism. The metal complexes were found to act as catalysts in Suzuki-Miyaura couplings, with the Pd(II) derivatives showing better catalytic activity compared to the Ni(II) analogues.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Svetlana G. Churusova, Diana V. Aleksanyan, Ekaterina Yu. Rybalkina, Evgenii I. Gutsul, Alexander S. Peregudov, Zinaida S. Klemenkova, Yulia V. Nelyubina, Anastasiya G. Buyanovskaya, Vladimir A. Kozlov
Summary: A new metal-based pincer ligand was designed and synthesized, and the resulting complexes showed high cytotoxicity against multiple cancer cell lines, indicating the potential to overcome drug resistance.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Eva Sanchez-Perez, Fernando Santos-Escobar, J. Felix Gutierrez-Corona, Kazimierz Wrobel, Katarzyna Wrobel, Oracio Serrano
Summary: This work describes a serendipitous self-assembly synthesis of non-symmetrical CNN-platinacycle pincer complexes, with an early formation and detection of hydride species. The synthesis involves a formal C-H bond activation and an earlier C-N bond formation, achieved via C-Br bond excision. Experimental results show that the nature of the Pt(II)-starting material does not significantly affect the reaction pathway, and the best yields are achieved using stoichiometric amounts of K2PtCl4, appropriate Schiff base ligand and aniline at 70 degrees C for three days.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Applied
Pennamuthiriyan Anandaraj, Sundar Saranya, Rengan Ramesh
Summary: An efficient method for the sustainable construction of pharmaceutically important benzothiazole derivatives from primary alcohols and 2-aminothiophenol using Pd(II)N<^>N<^>S pincer type catalysts has been described. The catalytic system allows for the synthesis of benzothiazoles via C-S and C-N bond formation with excellent yields. The use of an abundant and inexpensive alcohol as the starting material, along with the minimal production of water and hydrogen gas as by-products, demonstrates the sustainability of this methodology.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Sutthida Wongsuwan, Jaruwan Chatwichien, Weekit Sirisaksoontorn, Kittipong Chainok, Apisit Songsasen, Ratanon Chotima
Summary: Novel Pd(ii) pincer complexes were synthesized and characterized. The complexes showed strong binding affinity to DNA and BSA. They also exhibited significant anticancer activity and selectivity against different human cancer cell lines, making them promising candidates for novel anticancer drug development.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Dipankar Panigrahi, Vasudevan Subramaniyan, Ganesan Mani
Summary: In this study, a one-pot reaction was used to synthesize 1,3-bis((3,5-dimethyl-1H-pyrazol-1-yl)methyl)hexahydropyrimidine 1 with excellent yield, along with its derivatives. Various trans chelated complexes were obtained under different reaction conditions, demonstrating rigid or fluxional properties based on their structures. The compounds were well characterized by spectroscopic and X-ray methods, providing insights into their formation and properties.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Saul F. Teloxa, Miguel Mellado-Hidalgo, Stuart C. D. Kennington, Pedro Romea, Felix Urpi, Gabriel Aullon, Merce Font-Bardia
Summary: A direct and asymmetric aldol reaction between N-azidoacetyl-1,3-thiazolidine-2-thione and aromatic aldehydes catalyzed by a chiral nickel(II)-Tol-BINAP complex has been developed. The reaction gives anti alpha-azido-beta-silyloxy adducts with excellent stereocontrol and high yields. The removal of thiazolidinethione allows for the synthesis of a wide array of enantiomerically pure derivatives, providing a new route to di- and tripeptide blocks containing a beta-aryl-beta-hydroxy-alpha-amino acid.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Inorganic & Nuclear
Curtis C. Ho, Angus Olding, Rebecca O. Fuller, Allan J. Canty, Nigel T. Lucas, Alex C. Bissember
Summary: The study reveals that a nickel(I)/(III) cycle is involved in the Suzuki-Miyaura Csp(2)-Csp(2) cross-coupling reaction, with single-electron pathways likely operating in this transformation.
Article
Chemistry, Multidisciplinary
Princi Gupta, Suchithra Madhavan, Manmohan Kapur
Summary: In this study, a method for distal C-H functionalization of monosubstituted ferrocenes using an easily removable directing group under a Pd-II/ mono-N-protected amino-acid ligand catalytic system is reported. The synthetic protocol allows for the synthesis of ferrocene 1,3-derivatives with broad scope in olefins, by functionalizing ferrocenyl methylamine in moderate to good yields through a highly strained ferrocene appended 12-membered palladacycle intermediate.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Multidisciplinary Sciences
Aydin Aktas, Gul Yakali, Yeliz Demir, Ilhami Gulcin, Muhittin Aygun, Yetkin Gok
Summary: This study reports the synthesis of a series of palladium-based complexes bearing N-heterocyclic carbene (NHC) ligand, characterizes their properties and structures, and investigates their inhibition effects on biological enzymes.
Article
Chemistry, Physical
Arthur Flaget, Cheng Zhang, Clement Mazet
Summary: Ni-catalyzed enantioselective hydrofunctionalizations of conjugated dienes are challenging reactions that require addressing multiple aspects of selective catalysis. However, the value-added nature of the obtained chiral derivatives and the use of an earth-abundant transition metal have led to increased interest in this field. This Perspective provides an overview of the developments in this area, emphasizing the nature of the hydrofunctionalization agent.
Article
Multidisciplinary Sciences
Shuizhong Wang, Kaili Zhang, Helong Li, Ling-Ping Xiao, Guoyong Song
Summary: An atomically dispersed Ru catalyst has been developed for efficient cleavage of C-O bonds in C-lignin without hydrogenation of C=C bonds, resulting in high yields of propenylcatechol with high TONs.
NATURE COMMUNICATIONS
(2021)
Article
Agricultural Engineering
Chunquan Liu, Shuizhong Wang, Bo Wang, Guoyong Song
Summary: By catalytic hydrogenolysis of castor seed coats with deep eutectic solvents, naturally grown C-lignin can be extracted and depolymerized into monomeric catechols with high efficiency. High selectivity towards 4-propyl catechol was observed in DESs reactions, providing an efficient step for producing valuable catechol compounds.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Chemistry, Multidisciplinary
Weihong Song, Qinglian Du, Xiancheng Li, Shuizhong Wang, Guoyong Song
Summary: Catechyl lignin (C-lignin) is a promising biopolymer for the synthesis of bioactive molecules. Diversified transformations of propenylcatechol, a depolymerized product of C-lignin, were reported, resulting in the preparation of functional molecular skeletons for pharmaceuticals and bioactive molecules. The study demonstrated the low carbon footprint and high-quality production of bioactive molecules from C-lignin.
Article
Multidisciplinary Sciences
Zhenzhen Liu, Helong Li, Xueying Gao, Xuan Guo, Shuizhong Wang, Yunming Fang, Guoyong Song
Summary: Producing monomeric phenols from lignin biopolymer depolymerization in a detachable and efficient manner has attracted significant attention for the fullest utilization of sustainable lignocellulosic biomass. In this study, a low-loaded and highly dispersed Ru anchored on a chitosan-derived N-doped carbon catalyst (RuN/ZnO/C) is reported. This catalyst exhibits outstanding performance in the reductive catalytic fractionation of lignocellulose, achieving nearly theoretical maximum yields of phenolic monomers from lignin. The selectivity towards propyl end-chained guaiacol and syringol allows for easy purification, and the process leaves high retention of (hemi)cellulose for enzymatic hydrolysis. The good stability and transformation of Ru species contribute to the effectiveness of the catalyst. Time-course experiments and reactivity screening shed light on the mechanism. Overall, this work opens up new possibilities for the valorization of lignin and the economic feasibility of lignocellulosic biomass.
NATURE COMMUNICATIONS
(2022)
Article
Green & Sustainable Science & Technology
Xueying Gao, Helong Li, Shuizhong Wang, Zhenzhen Liu, Jian-feng Ma, Xing-e Liu, Guoyong Song
Summary: A catalyst composed of low-loading, sub-nanoscaled Ru species and multifarious acidic centers on amorphous-silica-alumina is reported, showing excellent activity, selectivity, and stability in the hydrodeoxygenation of lignin-derived phenolics into cyclohexanes. The catalytic performance is linearly related to the total acidities of the catalyst, indicating a synergistic interaction between the metallic and acidic components, enabling the efficient conversion of lignin-derived compounds into cyclohexanes.
Article
Polymer Science
Yihan Wang, Shihao Su, Guoyong Song
Summary: In this study, lignins were isolated from different parts of the castor plant and their structural features were investigated. The results showed that the endocarp and epicarp lignins had higher yields and selectivity of aromatic monomers. This work highlights the differences in lignins from various parts of the castor plant and provides a solid theory for the high-value utilization of the whole plant.
Article
Engineering, Multidisciplinary
Qingru Shen, Shuizhong Wang, Guoyong Song
Summary: In this study, a unique crystallite structure of C-lignin nanoparticles was discovered, and compositing with PVA resulted in materials with improved mechanical properties and various desirable characteristics. This work introduces a novel sustainable building block for strong polymeric materials and discovers a new route for the valorization of waste biomass.
COMPOSITES PART B-ENGINEERING
(2023)
Editorial Material
Green & Sustainable Science & Technology
Shuizhong Wang, Guoyong Song
Summary: Aromatic compounds are widely used in daily life, but their production relies heavily on fossil resources. A new strategy has been developed to synthesize benzenoid aromatics from bioderived feedstock, offering a more sustainable approach to aromatic production.
NATURE SUSTAINABILITY
(2023)
Article
Chemistry, Multidisciplinary
Jia Shi, Shuizhong Wang, Helong Li, Guoyong Song
Summary: Lignin, a renewable aromatic resource, can be selectively fragmented into hydroxycinnamic derivatives over a ZnMoO4/MCM-41 catalyst, which can then be converted into aromatic diesters. These diesters, when copolymerized with holocellulose-derived compounds, result in aliphatic-aromatic polyesters with controllable properties. The copolyesters can be fully converted into monomers, demonstrating excellent recyclability. This study provides a novel route for the synthesis of functional polymers from sustainable biomass.
Article
Chemistry, Multidisciplinary
Shihao Su, Fan-shu Cao, Shuizhong Wang, Qingru Shen, Gen Luo, Qiang Lu, Guoyong Song
Summary: This study demonstrates for the first time that tris(pentafluorophenyl)borane can efficiently catalyze the depolymerization of C-lignins containing benzodioxane structures, resulting in high yields of catechol derivatives at room temperature and ambient pressure. This method provides an economic and environmentally-friendly approach for the production of catechols from biomass waste.
Review
Chemistry, Multidisciplinary
Shuizhong Wang, Qingru Shen, Shihao Su, Jinxing Lin, Guoyong Song
Summary: This review provides recent advances in C-lignin research, including biosynthesis, separation and characterization, and valorization. Several next steps to further promote the development of C-lignin are also proposed.
TRENDS IN CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Jiayu Zhang, Wenshuang Huang, Kailing Han, Guoyong Song, Shaowei Hu
Summary: A series of first-row early transition metal dialkyl complexes bearing pincer ligands have been synthesized and their activities in styrene polymerization have been explored.
DALTON TRANSACTIONS
(2022)
Review
Chemistry, Multidisciplinary
Lu Qu, Xia Jiang, Zihao Zhang, Xiang-gang Zhang, Guo-yong Song, Hua-lin Wang, Yuan-ping Yuan, Yu-long Chang
Summary: This article reviews the model compounds, catalysts, and equipment involved in the hydrodeoxygenation (HDO) of bio-oils, aiming to summarize the progress in the utilization of the HDO process and provide useful insights for the efficient practical application of bio-oils.
Article
Chemistry, Multidisciplinary
Shihao Su, Shuizhong Wang, Guoyong Song
Summary: The study focused on finding efficient methods for disassembling C-lignin and G/S lignin in Euphorbiaceae seed coats, with the extraction by dilute HCl in dioxane being established as the optimized process. The isolated lignin samples were characterized by NMR spectroscopic analyses to mainly consist of benzodioxane units. The disassembled C-lignin samples showed high selectivity in producing catechylpropanol products through Pd/C-catalyzed hydrogenolysis, outperforming feedstocks containing both C and G/S lignins in terms of catalytic activity and selectivity.
Review
Chemistry, Multidisciplinary
Han-Min Wang, Tong-Qi Yuan, Guo-Yong Song, Run-Cang Sun
Summary: The excessive use of petroleum-based non-biodegradable plastic products has led to severe environmental pollution and ecological problems, prompting the development of biodegradable and renewable alternative materials. Lignin, a plentiful aromatic polymer with excellent biodegradability and biocompatibility, has shown great potential for creating diverse functional and sustainable materials to replace plastics. Recent advancements in the preparation and utilization of lignin-derived biodegradable film materials have garnered significant attention for their applications in sensors, energy storage systems, packaging, and biomedical materials.
