期刊
ORGANIC LETTERS
卷 12, 期 14, 页码 3144-3147出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol101062f
关键词
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资金
- National Natural Science Foundation of China [30925039]
- Ministry of Science and Technolgy of China [2009CB522302, 2008ZX09401-05, 2009ZX09302-004]
Cytosporolides A-C (1-3), three caryophyllene-derived meroterpenoids with a unique peroxylactone skeleton, were isolated from cultures of the fungus Cytospora sp. Their structures were elucidated by NMR spectroscopy, and the absolute configuration of the 5,6-diol moiety in 1 was assigned using Snatzke's method. Compounds 1-3 showed significant antimicrobial activity against the Gram-positive bacteria Staphylococcus aureus and Streptococcus pneumoniae.
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