Superacid synthesized tertiary benzenesulfonamides and benzofuzed sultams act as selective hCA IX inhibitors: toward understanding a new mode of inhibition by tertiary sulfonamides

New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides

(2013) Benoît Métayer et al.   CHEMICAL COMMUNICATIONS

Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors

(2013) Giuseppina De Simone et al.   Expert Opinion on Drug Discovery

Selective Anti-Markovnikov Cyclization and Hydrofluorination Reaction in Superacid HF/SbF5: A Tool in the Design of Nitrogen-Containing (Fluorinated) Polycyclic Systems

(2013) Guillaume Compain et al.   JOURNAL OF ORGANIC CHEMISTRY

Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII

(2012) Fabrizio Carta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: New selective tumor-associated carbonic anhydrase inhibitors

(2012) Guillaume Compain et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Stereoselective hydrofluorination of ynamides: a straightforward synthesis of novel α-fluoroenamides

(2012) Guillaume Compain et al.   CHEMICAL COMMUNICATIONS

Anti-Markovnikov additions to N-allylic derivatives involving ammonium–carbenium superelectrophiles

(2012) Guillaume Compain et al.   CHEMICAL COMMUNICATIONS

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

(2012) Kaspars Tars et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel therapies for glaucoma: a patent review 2007 – 2011

(2011) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Selective Synthesis ofgem-Chlorofluorinated Nitrogen-Containing Derivatives after Superelectrophilic Activation in Superacid HF/SbF5

(2011) Fei Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide

(2010) Anna Di Fiore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors

(2010) Claudiu T. Supuran   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Polyamines Inhibit Carbonic Anhydrases by Anchoring to the Zinc-Coordinated Water Molecule

(2010) Fabrizio Carta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Superelectrophilic Activation in Superacid HF/SbF5and Synthesis of Benzofused Sultams

(2010) Fei Liu et al.   ORGANIC LETTERS

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

(2009) Alfonso Maresca et al.   JOURNAL OF MEDICINAL CHEMISTRY

Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors#

(2009) Alfonso Maresca et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

(2009) V. Alterio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclisation/fluorination of nitrogen containing dienes in superacid HF–SbF5: a new route to 3- and 4-fluoropiperidines

(2008) Emilie Vardelle et al.   CHEMICAL COMMUNICATIONS

Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding

(2008) Vijay M. Krishnamurthy et al.   CHEMICAL REVIEWS

Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

(2008) John F. Domsic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes

(2008) Mika Hilvo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

(2008) Anna Di Fiore et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Carbonic anhydrase IX: A new druggable target for the design of antitumor agents

(2007) Jean-Yves Winum et al.   MEDICINAL RESEARCH REVIEWS