A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles

Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers

(2012) Xin Huang et al.   CHEMICAL COMMUNICATIONS

Enantioselective Construction of Spiro[2H-pyran-3,4′-indoline] by a Systematic Michael/Reduction/Cyclization Sequence Triggered by the Asymmetric Conjugate Addition of Ketones to Isatylidenemalononitriles

(2012) Hua Zhao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Three-Component Domino Reaction of Alkynyl Aldehydes with Oxindoles

(2012) Ding Du et al.   ORGANIC LETTERS

Organocatalytic Asymmetric α-Amination of Unprotected 3-Aryl and 3-Aliphatic Substituted Oxindoles using Di-tert-butyl Azodicarboxylate

(2011) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Iron-Catalyzed CH Fuctionalization of Indoles

(2011) Yan Cai et al.   ADVANCED SYNTHESIS & CATALYSIS

Gold Catalysis: Alkyl Migration in the Addition of Alcohols to Nitriles

(2011) Nada Ibrahim et al.   ADVANCED SYNTHESIS & CATALYSIS

Facile and Efficient Enantioselective Hydroxyamination Reaction: Synthesis of 3-Hydroxyamino-2-Oxindoles Using Nitrosoarenes

(2011) Ke Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application in the Enantioselective Total Synthesis of (+)-Folicanthine

(2011) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dioxindole in Asymmetric Catalytic Synthesis: Routes to Enantioenriched 3-Substituted 3-Hydroxyoxindoles and the Preparation of Maremycin A

(2011) Giulia Bergonzini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins

(2011) Li-Hui Sun et al.   CHEMICAL COMMUNICATIONS

Nickel(ii)-catalyzed diastereoselective [3+2] cycloaddition of N-tosyl-aziridines and aldehydes via selective carbon–carbon bond cleavage

(2011) Xingxing Wu et al.   CHEMICAL COMMUNICATIONS

Organocatalytic enantioselective conjugate addition of ketones to isatylidine malononitriles

(2011) Lu Liu et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

(2011) Yun-Lin Liu et al.   CHEMICAL COMMUNICATIONS

A Highly Efficient Friedel-Crafts Reaction of 3-Hydroxyoxindoles and Aromatic Compounds to 3,3-Diaryl and 3-Alkyl-3-aryloxindoles Catalyzed by Hg(ClO4)2⋅3 H2O

(2011) Feng Zhou et al.   Chemistry-An Asian Journal

Ritter Reaction: Recent Catalytic Developments

(2011) Amandine Guérinot et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin

(2011) Alessandro Sacchetti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective organocatalytic oxyamination of unprotected 3-substituted oxindoles

(2011) Xavier Companyó et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric hydroxyamination of oxindoles catalyzed by chiral bifunctional tertiary aminethiourea: construction of 3-amino-2-oxindoles with quaternary stereocenters

(2011) Li-Na Jia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Highly Functionalized Chiral 3,3′-Disubstituted Oxindoles via an Organocatalytic Enantioselective Michael Addition of Nitroalkanes to Indolylidenecyanoacetates

(2011) Lu Liu et al.   ORGANIC LETTERS

Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone

(2011) Yu-Bao Lan et al.   ORGANIC LETTERS

Chemoselectivities in the Platinum-Catalyzed Hydrative Carbocyclizations of Oxo-Alkyne-Nitrile Functionalities

(2011) Anupam Mukherjee et al.   ORGANIC LETTERS

A Hg(ClO4)2·3H2O Catalyzed Sakurai–Hosomi Allylation of Isatins and Isatin Ketoimines Using Allyltrimethylsilane

(2011) Zhong-Yan Cao et al.   ORGANIC LETTERS

Enantioselective Recognition of α-Hydroxycarboxylic Acids andN-Boc-Amino Acids by Counterion-Displacement Assays with a Chiral Nickel(II) Complex

(2011) Xuan He et al.   ORGANIC LETTERS

Trifluoroacetic Acid-Promoted Synthesis of 3-Hydroxy, 3-Amino and Spirooxindoles from α-Keto-N-Anilides

(2011) Ioulia Gorokhovik et al.   ORGANIC LETTERS

1,3-Dipolar Cycloaddition of Hydrazones with α-Oxo-ketenes: A Three-Component Stereoselective Entry to Pyrazolidinones and an Original Class of Spirooxindoles

(2011) Marc Presset et al.   ORGANIC LETTERS

Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins

(2011) Miao Ding et al.   Chemical Science

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Enantioselective Synthesis of Spirocyclic Oxindole-β-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins

(2010) Xiao-Na Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Perchloric Acid and Its Salts: Very Powerful Catalysts in Organic Chemistry†

(2010) Renato Dalpozzo et al.   CHEMICAL REVIEWS

Organocatalytic Tandem Reaction to Construct Six-Membered Spirocyclic Oxindoles with Multiple Chiral Centres through a Formal [2+2+2] Annulation

(2010) Kun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

New Chiral N-Heterocyclic Carbene Ligands in Palladium-Catalyzed α-Arylations of Amides: Conformational Locking through Allylic Strain as a Device for Stereocontrol

(2010) Yi-Xia Jia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Synthesis of 3-Amino-2-oxindole Derivatives: Catalytic Asymmetric α-Amination of 3-Substituted 2-Oxindoles with a Chiral Scandium Complex

(2010) Zhigang Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indium-Promoted Allylation Reaction of Imino-Isatins in Aqueous Media: Synthesis of Quaternary 3-Aminooxindoles

(2010) Benito Alcaide et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Regioselective Synthesis of Novel Spiropyrrolidines and Spirothiapyrrolizidines Through Multicomponent 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides

(2010) Hai Liu et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-oxindoles via Morita−Baylis−Hillman Reaction

(2010) Yun-Lin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of 3-Aminooxindoles: Enantiofacial Selectivity Switch in Bimetallic vs Monometallic Schiff Base Catalysis

(2010) Shinsuke Mouri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reaction

(2010) Yun-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Organocatalytic α-Amination Reactions of Aryl Oxindoles: Developing Designer Multifunctional Alkaloid Catalysts

(2010) Tommy Bui et al.   ORGANIC LETTERS

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

The spiropiperidine-3,3′-oxindole scaffold: a type II β-turn peptide isostere

(2010) Giordano Lesma et al.   TETRAHEDRON

Asymmetric organocatalytic N-nitroso-aldol reaction of oxindoles

(2010) Tao Zhang et al.   TETRAHEDRON-ASYMMETRY

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

(2009) Zi-Qing Qian et al.   CHEMICAL COMMUNICATIONS

Diastereoselective Ritter reactions of chiral secondary benzylic alcohols

(2009) Philipp Rubenbauer et al.   CHEMICAL COMMUNICATIONS

Green Chemistry: Principles and Practice

(2009) Paul Anastas et al.   CHEMICAL SOCIETY REVIEWS

An Efficient and Scalable Ritter Reaction for the Synthesis oftert-Butyl Amides

(2009) Jean C. Baum et al.   JOURNAL OF ORGANIC CHEMISTRY

Grignard Addition to Imines Derived from Isatine: A Method for the Asymmetric Synthesis of Quaternary 3-Aminooxindoles

(2009) Giordano Lesma et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Asymmetric Hetero-Claisen Approach to 3-Alkyl-3-aryloxindoles

(2009) Nicolas Duguet et al.   ORGANIC LETTERS

Highly Enantioselective and Organocatalytic α-Amination of 2-Oxindoles

(2009) Liang Cheng et al.   ORGANIC LETTERS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

A robust, efficient catalyst system for enolate arylation leading to quaternary 3-aminooxindoles

(2009) Emma L. Watson et al.   TETRAHEDRON LETTERS

Asymmetric Intramolecular Oxa-Michael Addition of Activated α,β-Unsaturated Ketones Catalyzed by a ChiralN,N′-Dioxide Nickel(II) Complex: Highly Enantioselective Synthesis of Flavanones

(2008) Lijia Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

o-Benzenedisulfonimide as a Reusable Brønsted Acid Catalyst for Ritter-Type Reactions

(2008) Margherita Barbero et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Facile and General Synthesis of Quaternary 3-Aminooxindoles

(2008) Stephen P. Marsden et al.   ORGANIC LETTERS

Green chemistry for chemical synthesis

(2008) C.-J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA