Organic fluorine as a polypeptide building element: in vivo expression of fluorinated peptides, proteins and proteomes

Structural basis for the enhanced stability of highly fluorinated proteins

(2012) B. C. Buer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Congeneric Lantibiotics from Ribosomal In Vivo Peptide Synthesis with Noncanonical Amino Acids

(2011) Florian Oldach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Incorporation of Multiple Noncanonical Amino Acids into Proteins

(2011) Michael G. Hoesl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyruvate Is the Source of the Two Carbons That Are Required for Formation of the Imidazoline Ring of 4-Demethylwyosine

(2011) Anthony P. Young et al.   BIOCHEMISTRY

Enhanced Refoldability and Thermoactivity of Fluorinated Phosphotriesterase

(2011) Peter James Baker et al.   CHEMBIOCHEM

Rational Design of Protein Stability: Effect of (2S,4R)-4-Fluoroproline on the Stability and Folding Pathway of Ubiquitin

(2011) Maria D. Crespo et al.   PLoS One

A Highly Active DNA Polymerase with a Fluorous Core

(2010) Bastian Holzberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Double and Triple Labeling of Proteins Using Synthetic Amino Acids

(2010) Sandra Lepthien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-specific protein backbone and side-chain NMR chemical shift and relaxation analysis of human vinexin SH3 domain using a genetically encoded 15 N/ 19 F-labeled unnatural amino acid

(2010) Pan Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Site-Specific Incorporation of Fluorotyrosines into Proteins inEscherichia coliby Photochemical Disguise

(2010) Bryan J. Wilkins et al.   BIOCHEMISTRY

Thermodynamic Consequences of Incorporating 4-Substituted Proline Derivatives into a Small Helical Protein

(2010) Tong-Yuan Zheng et al.   BIOCHEMISTRY

Generating Permissive Site-Specific Unnatural Aminoacyl-tRNA Synthetases

(2010) Shigeki J. Miyake-Stoner et al.   BIOCHEMISTRY

Engineering Protein Sequence Composition for Folding Robustness Renders Efficient Noncanonical Amino acid Incorporations

(2010) Soundrarajan Nagasundarapandian et al.   CHEMBIOCHEM

Parallel Incorporation of Different Fluorinated Amino Acids: On the Way to “Teflon” Proteins

(2010) Lars Merkel et al.   CHEMBIOCHEM

Lipase Congeners Designed by Genetic Code Engineering

(2010) Michael G. Hoesl et al.   ChemCatChem

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Azatryptophans as tools to study polarity requirements for folding of green fluorescent protein

(2010) Michael Georg Hoesl et al.   JOURNAL OF PEPTIDE SCIENCE

Replacing 32 Proline Residues by a Noncanonical Amino Acid Results in a Highly Active DNA Polymerase

(2010) Bastian Holzberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair

(2010) Susan M. Hancock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Residue-specific global fluorination of Candida antarctica lipase B in Pichia pastoris

(2010) Nediljko Budisa et al.   Molecular BioSystems

Genetic Code Mutations: The Breaking of a Three Billion Year Invariance

(2010) Wai-Kin Mat et al.   PLoS One

Stereoelectronic and steric effects in side chains preorganize a protein main chain

(2010) M. D. Shoulders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of the genetic code: Site-directed p-fluoro-phenylalanine incorporation in Escherichia coli

(2010) Rolf Furter   PROTEIN SCIENCE

Site-specific19F NMR chemical shift and side chain relaxation analysis of a membrane protein labeled with an unnatural amino acid

(2010) Pan Shi et al.   PROTEIN SCIENCE

Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds

(2009) Hsien-Ming Lee et al.   ACS Chemical Biology

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Engineering Protein Stability and Specificity Using Fluorous Amino Acids: The Importance of Packing Effects

(2009) Benjamin C. Buer et al.   BIOCHEMISTRY

19F NMR Studies of α-Synuclein Conformation and Fibrillation

(2009) Conggang Li et al.   BIOCHEMISTRY

Positional effects of monofluorinated phenylalanines on histone acetyltransferase stability and activity

(2009) Natalya Voloshchuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effects of Fluorination on the Folding Kinetics of a Heterodimeric Coiled Coil

(2009) Mario Salwiczek et al.   CHEMBIOCHEM

3S-Fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR

(2009) Colin A. Thomas et al.   CHEMICAL COMMUNICATIONS

Site-specific labeling of proteins with NMR-active unnatural amino acids

(2009) David H. Jones et al.   JOURNAL OF BIOMOLECULAR NMR

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

(2009) Travis S. Young et al.   JOURNAL OF MOLECULAR BIOLOGY

Effect of Highly Fluorinated Amino Acids on Protein Stability at a Solvent-Exposed Position on an Internal Strand of Protein G B1 Domain

(2009) Hsien-Po Chiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein19F NMR inEscherichia coli

(2009) Conggang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity

(2009) Audrey L. Stokes et al.   Molecular BioSystems

Incorporation of unnatural amino acids for synthetic biology

(2009) Natalya Voloshchuk et al.   Molecular BioSystems

Stereoelectronic effects on the transition barrier of polyproline conformational interconversion

(2009) Yi-Chun Chiang et al.   PROTEIN SCIENCE

Conformational Preferences of Substrates for Human Prolyl 4-Hydroxylase†

(2008) Kelly L. Gorres et al.   BIOCHEMISTRY

The Fluorous Effect in Proteins: Properties of α4F6, a 4-α-Helix Bundle Protein with a Fluorocarbon Core†

(2008) Lindsey M. Gottler et al.   BIOCHEMISTRY

Photostability of green and yellow fluorescent proteins with fluorinated chromophores, investigated by fluorescence correlation spectroscopy

(2008) S. Veettil et al.   BIOPHYSICAL CHEMISTRY

Intracellular uptake and inhibitory activity of aromatic fluorinated amino acids in human breast cancer cells

(2008) Christoph Giese et al.   ChemMedChem

19F NMR applications in chemical biology

(2008) Steven L. Cobb et al.   JOURNAL OF FLUORINE CHEMISTRY

Effects of tryptophan residue fluorination on streptavidin stability and biotin–streptavidin interactions via molecular dynamics simulations

(2008) Jarosław J. Panek et al.   JOURNAL OF MOLECULAR MODELING

In vivoIncorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

(2008) Susan E. Cellitti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Fluorous Arsenal: Tetrafluorinated Phenylalanines for Protein Design

(2008) Hong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline

(2008) Thomas Steiner et al.   PLoS One

Red fluorescent protein variants with incorporated non-natural amino acid analogues

(2008) A. Goulding et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Solid state 19F NMR parameters of fluorine-labeled amino acids. Part I: Aromatic substituents

(2007) Ulrich H.N. Dürr et al.   JOURNAL OF MAGNETIC RESONANCE