期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 23, 页码 8171-8177出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob06251d
关键词
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资金
- Generalitat de Cataluna [2009SGR871]
- MICINN [AGL2009-13452-C02-01]
Both enantiomers of several phenylethylamines, structurally related to amphetamine, have been prepared in good yields and excellent enantiomeric purity by enzymatic kinetic resolution using CAL-B and ethyl methoxyacetate as the acyl donor. In the case of the 4-hydroxyderivative of amphetamine (compound 4i), the S enantiomer racemized possibly in a dynamic kinetic resolution (DKR) under the enzymatic conditions used.
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