Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

(2014) Ilona Kryczek et al.   IMMUNITY

γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer

(2014) Pin Wu et al.   IMMUNITY

Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis

(2014) Xinyang Song et al.   IMMUNITY

Autocrine Regulation of IL-21 Production in Human T Lymphocytes

(2014) F. Caprioli et al.   JOURNAL OF IMMUNOLOGY

IL-21 induces IL-22 production in CD4+ T cells

(2014) Ada Yeste et al.   Nature Communications

STAT3 Target Genes Relevant to Human Cancers

(2014) Richard Carpenter et al.   Cancers

Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically

(2013) Tracy L. Putoczki et al.   CANCER CELL

Early signaling events that underlie fate decisions of naive CD4+T cells toward distinct T-helper cell subsets

(2013) Hidehiro Yamane et al.   IMMUNOLOGICAL REVIEWS

Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

(2013) Stefanie Kirchberger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of IL-17A in the development of colitis-associated cancer

(2012) Y. S. Hyun et al.   CARCINOGENESIS

The Dual Role of Inflammation in Colon Carcinogenesis

(2012) Giovanni Monteleone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The split nature of tumor-infiltrating leukocytes

(2012) Telma Lança et al.   OncoImmunology

Prognostic and Predictive Impact of Intra- and Peritumoral Immune Infiltrates

(2011) W. H. Fridman et al.   CANCER RESEARCH

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

(2011) Marie Tosolini et al.   CANCER RESEARCH

Interleukin 21 controls tumour growth and tumour immunosurveillance in colitis-associated tumorigenesis in mice

(2011) D. Jauch et al.   GUT

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

(2011) Carmine Stolfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

(2010) W.-J. Chae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Worldwide Variations in Colorectal Cancer

(2009) M. M. Center et al.   CA-A CANCER JOURNAL FOR CLINICIANS

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity

(2009) H.-R. Yen et al.   JOURNAL OF IMMUNOLOGY

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid

(2007) Carmine Stolfi et al.   BIOCHEMICAL PHARMACOLOGY