Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

Phosphorylated Mnk1 and eIF4E Are Associated with Lymph Node Metastasis and Poor Prognosis of Nasopharyngeal Carcinoma

(2014) Jun Zheng et al.   PLoS One

mTOR Signaling Pathway in Penile Squamous Cell Carcinoma: pmTOR and peIF4E Over Expression Correlate with Aggressive Tumor Behavior

(2013) Carla Ferrandiz-Pulido et al.   JOURNAL OF UROLOGY

eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies

(2012) T. Alain et al.   CANCER RESEARCH

EIF4E over-expresses and enhances cell proliferation and cell cycle progression in nasopharyngeal carcinoma

(2012) Mengyan Wu et al.   MEDICAL ONCOLOGY

Cap-Dependent Translation Initiation Factor eIF4E: An Emerging Anticancer Drug Target

(2012) Yan Jia et al.   MEDICINAL RESEARCH REVIEWS

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway

(2012) L Adesso et al.   ONCOGENE

MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition

(2012) A Astanehe et al.   ONCOGENE

eIF4F suppression in breast cancer affects maintenance and progression

(2012) Z Nasr et al.   ONCOGENE

Detection of eukaryotic translation initiation factor 4E and its clinical significance in hepatocellular carcinoma

(2012) Xiao-Lin Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Emerging Therapeutics Targeting mRNA Translation

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anota: analysis of differential translation in genome-wide studies

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Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases

(2011) B. W. Konicek et al.   CANCER RESEARCH

MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-  Signaling Pathway in Human Glioblastoma

(2011) M. Grzmil et al.   CANCER RESEARCH

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer

(2011) F. Pettersson et al.   CLINICAL CANCER RESEARCH

Eukaryotic initiation factor 4F: a vulnerability of tumor cells

(2011) Teresa Lee et al.   Future Medicinal Chemistry

The roles of TGF-β signaling in carcinogenesis and breast cancer metastasis

(2011) Takeshi Imamura et al.   Breast Cancer

Loss of the 14-3-3σ Tumor Suppressor Is a Critical Event in ErbB2-Mediated Tumor Progression

(2011) Chen Ling et al.   Cancer Discovery

Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues

(2010) Songqing Fan et al.   CANCER BIOLOGY & THERAPY

Prognostic significance of expression of eukaryotic initiation factor 4E and 4E binding protein 1 in patients with pathological stage I invasive lung adenocarcinoma

(2010) Nobuhiko Seki et al.   LUNG CANCER

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

(2010) T. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of differential translation in genome wide studies

(2010) O. Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

(2010) L. Furic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival

(2009) J. R. Graff et al.   CANCER RESEARCH

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Overexpression of Phospho-eIF4E Is Associated with Survival through AKT Pathway in Non-Small Cell Lung Cancer

(2009) A. Yoshizawa et al.   CLINICAL CANCER RESEARCH

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

A Prospective Trial on Initiation Factor 4E (eIF4E) Overexpression and Cancer Recurrence in Node-Negative Breast Cancer

(2008) Neal Holm et al.   ANNALS OF SURGICAL ONCOLOGY

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH