Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway
出版年份 2012 全文链接
标题
Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway
作者
关键词
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出版物
ONCOGENE
Volume 32, Issue 23, Pages 2848-2857
出版商
Springer Nature
发表日期
2012-07-16
DOI
10.1038/onc.2012.306
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting Phosphoinositide 3-Kinase Pathways in Pancreatic Cancer – from Molecular Signalling to Clinical Trials
- (2012) Marco Falasca et al. Anti-Cancer Agents in Medicinal Chemistry
- Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases
- (2011) B. W. Konicek et al. CANCER RESEARCH
- The RNA-binding protein Sam68 is a multifunctional player in human cancer
- (2011) P. Bielli et al. ENDOCRINE-RELATED CANCER
- A High Proportion of DNA Variants of BRCA1 and BRCA2 Is Associated with Aberrant Splicing in Breast/Ovarian Cancer Patients
- (2010) D. J. Sanz et al. CLINICAL CANCER RESEARCH
- The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy
- (2010) Simona Pedrotti et al. EMBO JOURNAL
- The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting
- (2010) Scott E Kern et al. JOURNAL OF PATHOLOGY
- Negative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic Responses
- (2010) J. K. Altman et al. MOLECULAR PHARMACOLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
- (2010) T. Ueda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
- (2010) L. Furic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin
- (2009) S. Assouline et al. BLOOD
- eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival
- (2009) J. R. Graff et al. CANCER RESEARCH
- Overexpression of Phospho-eIF4E Is Associated with Survival through AKT Pathway in Non-Small Cell Lung Cancer
- (2009) A. Yoshizawa et al. CLINICAL CANCER RESEARCH
- HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
- (2009) Charles J. David et al. NATURE
- Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells
- (2008) Andrea Bianchini et al. CARCINOGENESIS
- The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)
- (2008) Maria Buxade Frontiers in Bioscience-Landmark
- Oral mTOR Inhibitor Everolimus in Patients With Gemcitabine-Refractory Metastatic Pancreatic Cancer
- (2008) Brian M. Wolpin et al. JOURNAL OF CLINICAL ONCOLOGY
- A missense mutation in the APC tumor suppressor gene disrupts an ASF/SF2 splicing enhancer motif and causes pathogenic skipping of exon 14
- (2008) Vânia Gonçalves et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Phosphorylation of eIF-4E positively regulates formation of the eIF-4F translation initiation complex following DNA damage
- (2007) Ying Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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