CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer

(2015) Gab-Yong Bae et al.   Oncotarget

Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK–Mediated Up-Regulation of MMP-2 and MMP-9

(2013) Qian-ze Dong et al.   AMERICAN JOURNAL OF PATHOLOGY

CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia

(2013) G. Malet-Engra et al.   CANCER RESEARCH

CIP4 coordinates with phospholipids and actin-associated proteins to localize to the protruding edge and produce actin ribs and veils

(2013) W. Saengsawang et al.   JOURNAL OF CELL SCIENCE

Fer Protein-Tyrosine Kinase Promotes Lung Adenocarcinoma Cell Invasion and Tumor Metastasis

(2013) Joseph Ahn et al.   MOLECULAR CANCER RESEARCH

mTOR Inhibitors Control the Growth of EGFR Mutant Lung Cancer Even after Acquiring Resistance by HGF

(2013) Daisuke Ishikawa et al.   PLoS One

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Role of CIP4 in high glucose induced epithelial--mesenchymal transition of rat peritoneal mesothelial cells

(2013) Jian Zhang et al.   RENAL FAILURE

The F-BAR Protein CIP4 Inhibits Neurite Formation by Producing Lamellipodial Protrusions

(2012) Witchuda Saengsawang et al.   CURRENT BIOLOGY

Inhibition of Cdc42-Interacting Protein 4 (CIP4) Impairs Osteosarcoma Tumor Progression

(2012) Nadezhda V. Koshkina et al.   CURRENT CANCER DRUG TARGETS

Cdc42-Interacting Protein-4 Promotes TGF-Β1-Induced Epithelial-Mesenchymal Transition and Extracellular Matrix Deposition in Renal Proximal Tubular Epithelial Cells

(2012) Shoujun Bai et al.   International Journal of Biological Sciences

Overcoming erlotinib resistance with tailored treatment regimen in patient-derived xenografts from naïve Asian NSCLC patients

(2012) Mengmeng Yang et al.   INTERNATIONAL JOURNAL OF CANCER

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

(2012) Shang-Jyh Kao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis

(2011) J. Hu et al.   JOURNAL OF CELL SCIENCE

Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling

(2011) Zixuan Li et al.   MOLECULAR CARCINOGENESIS

TAZ is a novel oncogene in non-small cell lung cancer

(2011) Z Zhou et al.   ONCOGENE

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Cdc42-Interacting Protein 4 Promotes Breast Cancer Cell Invasion and Formation of Invadopodia through Activation of N-WASp

(2010) C. S. Pichot et al.   CANCER RESEARCH

Non-small-cell lung cancer harbouring mutations in the EGFR kinase domain

(2010) Rafael Rosell et al.   Clinical & Translational Oncology

Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking

(2010) S. Koduru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

F-BAR-containing adaptor CIP4 localizes to early endosomes and regulates Epidermal Growth Factor Receptor trafficking and downregulation

(2009) Jinghui Hu et al.   CELLULAR SIGNALLING

Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

(2009) Tetsuya Mitsudomi et al.   FEBS Journal

The Cdc42-interacting Protein-4 (CIP4) Gene Knock-out Mouse Reveals Delayed and Decreased Endocytosis

(2009) Yanming Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

Structural Basis of Membrane Invagination by F-BAR Domains

(2008) Adam Frost et al.   CELL

Drosophila Cip4 and WASp Define a Branch of the Cdc42-Par6-aPKC Pathway Regulating E-Cadherin Endocytosis

(2008) Andrea Leibfried et al.   CURRENT BIOLOGY

EFC/F-BAR proteins and the N-WASP–WIP complex induce membrane curvature-dependent actin polymerization

(2008) Kazunari Takano et al.   EMBO JOURNAL

IncreasedEGFRGene Copy Number Detected by Fluorescent In Situ Hybridization Predicts Outcome in Non–Small-Cell Lung Cancer Patients Treated With Cetuximab and Chemotherapy

(2008) Fred R. Hirsch et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting RAS and PI3K in lung cancer

(2008) Julian Downward   NATURE MEDICINE