Pancreatic tumours escape from translational control through 4E-BP1 loss

eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies

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Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication

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The biological and therapeutic relevance of mRNA translation in cancer

(2011) Sarah P. Blagden et al.   Nature Reviews Clinical Oncology

Postnatal Deamidation of 4E-BP2 in Brain Enhances Its Association with Raptor and Alters Kinetics of Excitatory Synaptic Transmission

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Pancreatic Cancer

(2010) Manuel Hidalgo   NEW ENGLAND JOURNAL OF MEDICINE

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

(2010) T. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

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mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

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Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

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Phosphorylated 4E-BP1 Is Associated with Poor Survival in Melanoma

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4E-BP1 is a target of Smad4 essential for TGFβ-mediated inhibition of cell proliferation

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SUnSET, a nonradioactive method to monitor protein synthesis

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Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

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Oral mTOR Inhibitor Everolimus in Patients With Gemcitabine-Refractory Metastatic Pancreatic Cancer

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