Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion

(2012) Takaya Shimura et al.   BMC CANCER

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

(2012) Anne-Katrine Bonde et al.   BMC CANCER

Tumor microenvironment and breast cancer progression

(2012) Antonia Artacho-Cordón et al.   CANCER BIOLOGY & THERAPY

EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling

(2012) Kristy J. Wilson et al.   GROWTH FACTORS

Unknown

(2012) Salvatore Coniglio et al.   MOLECULAR MEDICINE

In Vivo Invasion of Head and Neck Squamous Cell Carcinoma Cells Does Not Require Macrophages

(2011) Tatiana Smirnova et al.   AMERICAN JOURNAL OF PATHOLOGY

Brief treatment with heparin-binding EGF-like growth factor, but not with EGF, is sufficient to accelerate epithelial wound healing

(2011) Michael A. Tolino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion

(2011) C. C. Mader et al.   CANCER RESEARCH

Mena invasive (MenaINV) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

(2011) Evanthia T. Roussos et al.   CLINICAL & EXPERIMENTAL METASTASIS

Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

(2011) E. T. Roussos et al.   JOURNAL OF CELL SCIENCE

A Critical Role for Macrophages in Promotion of Urethane-Induced Lung Carcinogenesis

(2011) R. Zaynagetdinov et al.   JOURNAL OF IMMUNOLOGY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis

(2011) T Smirnova et al.   ONCOGENE

LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling

(2011) Hui-Wen Lue et al.   PLoS One

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes

(2010) Vira V. Artym et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

HB-EGF orchestrates the complex signals involved in triple-negative and trastuzumab-resistant breast cancer

(2010) Fusanori Yotsumoto et al.   INTERNATIONAL JOURNAL OF CANCER

Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia

(2010) M. Oser et al.   JOURNAL OF CELL SCIENCE

Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context

(2010) Elizabeth J. Joslin et al.   Molecular BioSystems

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor

(2009) A. Patsialou et al.   CANCER RESEARCH

ERBB1 and ERBB2 Have Distinct Functions in Tumor Cell Invasion and Intravasation

(2009) D. Kedrin et al.   CLINICAL CANCER RESEARCH

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

(2009) Matthew Oser et al.   JOURNAL OF CELL BIOLOGY

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

(2009) Binzhi Qian et al.   PLoS One

Differential Effects of EGFR Ligands on Endocytic Sorting of the Receptor

(2009) Kirstine Roepstorff et al.   TRAFFIC

Heparin-binding epidermal growth factor–like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition

(2008) Hiroshi Yagi et al.   MOLECULAR CANCER THERAPEUTICS

Cortactin branches out: Roles in regulating protrusive actin dynamics

(2008) Amanda Gatesman Ammer et al.   CELL MOTILITY AND THE CYTOSKELETON