p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases

How protein kinases co-ordinate mitosis in animal cells

(2011) Hoi Tang Ma et al.   BIOCHEMICAL JOURNAL

CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis

(2011) Ying Wai Chan et al.   CELL CYCLE

Aurora B kinase inhibition in mitosis: Strategies for optimizing the use of Aurora kinase inhibitors such as AT9283

(2011) Jayne Curry et al.   CELL CYCLE

Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

(2011) M. G. Manfredi et al.   CLINICAL CANCER RESEARCH

Update on aurora kinase targeted therapeutics in oncology

(2011) Myke R Green et al.   Expert Opinion on Drug Discovery

Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics

(2011) Nadia Hégarat et al.   JOURNAL OF CELL BIOLOGY

Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01

(2011) K. F. On et al.   MOLECULAR CANCER THERAPEUTICS

MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel

(2010) T. Shimomura et al.   MOLECULAR CANCER THERAPEUTICS

Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks

(2009) Paul J. Scutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aurora Kinase A Inhibition Leads to p73-Dependent Apoptosis in p53-Deficient Cancer Cells

(2008) Altaf A. Dar et al.   CANCER RESEARCH

Aurora Kinases as Anticancer Drug Targets

(2008) O. Gautschi et al.   CLINICAL CANCER RESEARCH

The Kinetics of p53 ActivationVersusCyclin E Accumulation Underlies the Relationship between the Spindle-assembly Checkpoint and the Postmitotic Checkpoint

(2008) Ying Wai Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The consequences of tetraploidy and aneuploidy

(2008) Z. Storchova et al.   JOURNAL OF CELL SCIENCE