Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis
出版年份 2013 全文链接
标题
Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis
作者
关键词
-
出版物
ONCOGENE
Volume 33, Issue 22, Pages 2815-2825
出版商
Springer Nature
发表日期
2013-06-11
DOI
10.1038/onc.2013.235
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sox9 is required for prostate development and prostate cancer initiation
- (2015) Zhenhua Huang et al. Oncotarget
- ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
- (2013) Changmeng Cai et al. JOURNAL OF CLINICAL INVESTIGATION
- ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
- (2012) N. J. Clegg et al. CANCER RESEARCH
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- A transcriptional repressor co-regulatory network governing androgen response in prostate cancers
- (2012) Kern Rei Chng et al. EMBO JOURNAL
- Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
- (2012) Siu Chiu Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Androgen Receptor Serine 81 Phosphorylation Mediates Chromatin Binding and Transcriptional Activation
- (2012) Shaoyong Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stepwise androgen receptor dimerization
- (2012) M. E. van Royen et al. JOURNAL OF CELL SCIENCE
- In SilicoDiscovery of Androgen Receptor Antagonists with Activity in Castration Resistant Prostate Cancer
- (2012) Howard C. Shen et al. MOLECULAR ENDOCRINOLOGY
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy
- (2012) Charles J. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
- (2012) Y Li et al. ONCOGENE
- Doxycycline Regulated Induction of AKT in Murine Prostate Drives Proliferation Independently of p27 Cyclin Dependent Kinase Inhibitor Downregulation
- (2012) Hongyun Wang et al. PLoS One
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth
- (2011) David J. Mulholland et al. CANCER CELL
- Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
- (2011) Brett S. Carver et al. CANCER CELL
- Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
- (2011) C. Cai et al. CANCER RESEARCH
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
- (2011) Charles E Massie et al. EMBO JOURNAL
- Androgen receptor levels are upregulated by Akt in prostate cancer
- (2011) S. Ha et al. ENDOCRINE-RELATED CANCER
- Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy
- (2011) Changmeng Cai et al. ENDOCRINE-RELATED CANCER
- Alternatively spliced androgen receptor variants
- (2011) Scott M Dehm et al. ENDOCRINE-RELATED CANCER
- Cooperation between Polycomb and androgen receptor during oncogenic transformation
- (2011) J. C. Zhao et al. GENOME RESEARCH
- Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation
- (2011) Zi Fang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Androgen receptor-mediated gene repression
- (2011) Andreas Grosse et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Post-translational modification of the androgen receptor
- (2011) Daniel Gioeli et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Lysine Methylation and Functional Modulation of Androgen Receptor by Set9 Methyltransferase
- (2011) Soyoung Ko et al. MOLECULAR ENDOCRINOLOGY
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases
- (2011) Xiaotun Zhang et al. PLoS One
- Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
- (2011) A. Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor
- (2010) Raymond J. Andersen et al. CANCER CELL
- An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression
- (2010) Jindan Yu et al. CANCER CELL
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Evidence of Limited Contributions for Intratumoral Steroidogenesis in Prostate Cancer
- (2010) J. Hofland et al. CANCER RESEARCH
- SOX9 Elevation in the Prostate Promotes Proliferation and Cooperates with PTEN Loss to Drive Tumor Formation
- (2010) M. K. Thomsen et al. CANCER RESEARCH
- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
- (2010) Ankur Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- CDK9 Regulates AR Promoter Selectivity and Cell Growth through Serine 81 Phosphorylation
- (2010) Vicki Gordon et al. MOLECULAR ENDOCRINOLOGY
- Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4
- (2010) Eric Metzger et al. NATURE
- Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks
- (2010) Xionglei He et al. NATURE GENETICS
- Regulation of the androgen receptor by SET9-mediated methylation
- (2010) Luke Gaughan et al. NUCLEIC ACIDS RESEARCH
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination
- (2009) Kexin Xu et al. CANCER CELL
- Reactivation of Androgen Receptor-Regulated TMPRSS2:ERG Gene Expression in Castration-Resistant Prostate Cancer
- (2009) C. Cai et al. CANCER RESEARCH
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
- (2009) Qianben Wang et al. CELL
- Phase II Study of Androgen Synthesis Inhibition with Ketoconazole, Hydrocortisone, and Dutasteride in Asymptomatic Castration-Resistant Prostate Cancer
- (2009) M.-E. Taplin et al. CLINICAL CANCER RESEARCH
- Androgen Receptor Phosphorylation and Activity Are Regulated by an Association with Protein Phosphatase 1
- (2009) Shaoyong Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genomic Strategy for Targeting Therapy in Castration-Resistant Prostate Cancer
- (2009) Prateek Mendiratta et al. JOURNAL OF CLINICAL ONCOLOGY
- Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts
- (2009) Jennifer A. Locke et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer
- (2008) J. A. Locke et al. CANCER RESEARCH
- Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth
- (2008) R. B. Montgomery et al. CANCER RESEARCH
- SOX9 Is Expressed in Human Fetal Prostate Epithelium and Enhances Prostate Cancer Invasion
- (2008) H. Wang et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
- FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription
- (2008) Mathieu Lupien et al. CELL
- Targeting CYP17: established and novel approaches in prostate cancer
- (2008) Timothy A Yap et al. CURRENT OPINION IN PHARMACOLOGY
- Sox9 is required for prostate development
- (2008) Martin K. Thomsen et al. DEVELOPMENTAL BIOLOGY
- Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol
- (2008) Paulette R. Dillard et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor
- (2008) Myles C. Hodgson et al. MOLECULAR CANCER THERAPEUTICS
- Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
- (2008) E M Schaeffer et al. ONCOGENE
- Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules
- (2008) Q. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression
- (2008) B. Perillo et al. SCIENCE
- Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
- (2008) Scott A. Tomlins et al. NEOPLASIA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now