E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis

Exploring molecular genetics of bladder cancer: lessons learned from mouse models

(2012) I. Ahmad et al.   Disease Models & Mechanisms

Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells

(2012) Mangmang Li et al.   MOLECULAR CELL

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

(2011) Kunyoo Shin et al.   NATURE

Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis

(2011) I Ahmad et al.   Cell Death & Disease

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors

(2010) Ju-Seog Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways

(2010) Naoko Takebe et al.   Nature Reviews Clinical Oncology

β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation

(2010) I Ahmad et al.   ONCOGENE

A Functional Role of RB-Dependent Pathway in the Control of Quiescence in Adult Epidermal Stem Cells Revealed by Genomic Profiling

(2010) Corina Lorz et al.   Stem Cell Reviews and Reports

Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

(2009) Andrea Haegebarth et al.   AMERICAN JOURNAL OF PATHOLOGY

Urothelial carcinoma: Stem cells on the edge

(2009) William D. Brandt et al.   CANCER AND METASTASIS REVIEWS

On the Origin of Epidermal Cancers

(2009) Corina Lorz et al.   CURRENT MOLECULAR MEDICINE

E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells

(2009) Jean-Leon Chong et al.   NATURE

C/EBPα and β couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation

(2009) Rodolphe G. Lopez et al.   NATURE CELL BIOLOGY

Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

(2008) A. B. Martinez-Cruz et al.   CANCER RESEARCH

E2f3a and E2f3b Contribute to the Control of Cell Proliferation and Mouse Development

(2008) J.-L. Chong et al.   MOLECULAR AND CELLULAR BIOLOGY

Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage

(2008) Mirentxu Santos et al.   MOLECULAR CARCINOGENESIS

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

Constitutively Active Akt Induces Ectodermal Defects and Impaired Bone Morphogenetic Protein Signaling

(2007) Carmen Segrelles et al.   MOLECULAR BIOLOGY OF THE CELL

Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis

(2007) M. Fernanda Lara et al.   MOLECULAR CARCINOGENESIS

p107 acts as a tumor suppressor in pRb-deficient epidermis

(2007) M. Fernanda Lara et al.   MOLECULAR CARCINOGENESIS