Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation

Loss of RUNX3 Expression Correlates with Differentiation, Nodal Metastasis, and Poor Prognosis of Gastric Cancer

(2009) Ping-I. Hsu et al.   ANNALS OF SURGICAL ONCOLOGY

Helicobacter pylori causes runx3 gene methylation and its loss of expression in gastric epithelial cells, which is mediated by nitric oxide produced by macrophages

(2009) Yasumi Katayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Helicobacter pylori CagA activates NF-κB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination

(2009) Acacia Lamb et al.   EMBO REPORTS

Claudin-1 Has Tumor Suppressive Activity and Is a Direct Target of RUNX3 in Gastric Epithelial Cells

(2009) Ti Ling Chang et al.   GASTROENTEROLOGY

Helicobacter pylori and gastric carcinogenesis

(2009) Masanori Hatakeyama   JOURNAL OF GASTROENTEROLOGY

RUNX3 Attenuates β-Catenin/T Cell Factors in Intestinal Tumorigenesis

(2008) Kosei Ito et al.   CANCER CELL

SagA of CagA in Helicobacter pylori pathogenesis

(2008) Masanori Hatakeyama   CURRENT OPINION IN MICROBIOLOGY

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

(2008) N. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA