期刊
NUTRITION RESEARCH REVIEWS
卷 25, 期 2, 页码 288-301出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0954422412000182
关键词
Postprandial hyperglycaemia; Hypertriacylglycerolaemia; Endothelial function; Oxidative stress
Endothelial dysfunction is a turning point in the initiation and development of atherosclerosis and its complications and is predictive of future cardiovascular events. Ingestion of high-carbohydrate or high-fat meals often results in postprandial hyperglycaemia and/or hypertriacylglycerolaemia that may lead to a transient impairment in endothelial function. The present review will discuss human studies evaluating the impact of high-carbohydrate and high-fat challenges on postprandial endothelial function as well as the potential role of oxidative stress in such postprandial metabolic alterations. Moreover, the present review will differentiate the postprandial endothelial and oxidative impact of meals rich in varying fatty acid types.
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