Review
Public, Environmental & Occupational Health
Chao Xue, Juan Li, Mingqing Hao, Lihua Chen, Zuoxiu Chen, Zeli Tang, Huan Tang, Qian Fang
Summary: This study systematically evaluated the prevalence of subjective cognitive decline (SCD) among older Chinese adults. The results showed a high and widespread prevalence of SCD in this population, with variations in gender, age, BMI, geographic region, residency, occupation, education level, and marital status.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Biochemistry & Molecular Biology
Giuseppe Caruso, Justyna Godos, Sabrina Castellano, Agnieszka Micek, Paolo Murabito, Fabio Galvano, Raffaele Ferri, Giuseppe Grosso, Filippo Caraci
Summary: Carnosine, proposed as an anti-aging agent over 20 years ago, has shown antioxidant, anti-inflammatory, and anti-aggregation activity with neuroprotective effects in animal models of Alzheimer's disease. Global cognitive function was improved after 12 weeks of carnosine/anserine supplementation at a dose of 1 g/day in elderly subjects, while no effects were observed on depressive symptoms.
Review
Neurosciences
Diana Karamacoska, Ali Butt, Isabella H. K. Leung, Ryan L. Childs, Najwa-Joelle Metri, Vithya Uruthiran, Tiffany Tan, Angelo Sabag, Genevieve Z. Steiner-Lim
Summary: Exercise has positive effects on cognitive decline and dementia risk, but its neuronal effects in individuals with cognitive decline have not been thoroughly investigated. This systematic review found that exercise can improve global cognition and executive function, and is associated with neuronal adaptations in the brain. Further high-quality trials are needed to understand the functional relationship between exercise and brain health in populations at high risk of dementia.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Medicine, General & Internal
Leicia Iris de Assuncao Prado, Ana Lucia Junger, Leonardo Ferreira Caixeta, Matias Noll, Cesar de Oliveira, Erika Aparecida Silveira
Summary: This study aims to assess the effectiveness of treating dementia and cognitive decline with methylfolate supplementation in older adults. The main outcomes analyzed will be dementia and changes in cognitive function. Secondary outcomes, such as inflammatory markers and folic acid levels, will also be assessed.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cell Biology
Si Qi Yoong, Jinhua Lu, Huimin Xing, Bibek Gyanwali, Yue Qian Tan, Xi Vivien Wu
Summary: CSF Ng shows promising potential in predicting cognitive decline, especially in predicting MMSE decline in A beta+ mild cognitive impairment with high-quality evidence. It also has the ability to predict the decline of memory and executive function in mild cognitive impairment. The combination of CSF Ng and A beta 42 may also be a predictor of cognitive decline. More studies are needed to validate its use as an AD prognostic marker.
AGEING RESEARCH REVIEWS
(2021)
Review
Cardiac & Cardiovascular Systems
Swarna Vishwanath, Vazhma Qaderi, Claire J. Steves, Christopher M. Reid, Ingrid Hopper, Joanne Ryan
Summary: There is an association between heart failure (HF) and cognitive change and dementia. HF is not significantly associated with dementia, but increases the risk of cognitive impairment. Patients with HF perform worse on cognitive tests.
JOURNAL OF CARDIAC FAILURE
(2022)
Review
Geriatrics & Gerontology
Federica Cacciamani, Marion Houot, Geoffroy Gagliardi, Bruno Dubois, Sietske Sikkes, Gonzalo Sanchez-Benavides, Elena Denicolo, Jose Luis Molinuevo, Patrizia Vannini, Stephane Epelbaum
Summary: The study found that there was no significant difference in awareness of cognitive decline (ACD) between preclinical AD patients and MCI patients, but ACD was significantly poorer in patients with amnestic MCI and mild AD, with the worst ACD observed in individuals with mild AD. This suggests that ACD may decrease as the disease progresses.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Review
Food Science & Technology
Guangsu Zhu, Jianxin Zhao, Hao Zhang, Wei Chen, Gang Wang
Summary: Analysis of randomized controlled trials suggests that dietary supplementation with probiotics may improve cognitive function, particularly in individuals with mild cognitive impairment.
Review
Nutrition & Dietetics
Maria Bonvicini, Silvia Travaglini, Diana Lelli, Raffaele Antonelli Incalzi, Claudio Pedone
Summary: Citicoline has positive effects on cognitive function, but the overall quality of the studies is poor with significant risk of bias in favor of the intervention.
Review
Geriatrics & Gerontology
Sandra L. Kletzel, Pallavi Sood, Ahmed Negm, Patricia C. Heyn, Shilpa Krishnan, Joseph Machtinger, Xiaolei Hu, Hannes Devos
Summary: This study conducted a systematic review and meta-analysis on the effects of brain gaming interventions for improving cognitive functions in older adults with cognitive impairments. The findings suggest that brain gaming did not show significant improvements in standardized cognitive tests compared to control interventions.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Review
Multidisciplinary Sciences
Sherlyn Jemimah, Chahd Maher Musthafa Chabib, Leontios Hadjileontiadis, Aamna AlShehhi
Summary: Alzheimer's disease (AD) and mild cognitive impairment (MCI) are associated with significant gut dysbiosis. Through a meta-analysis and systematic review of 16S gut microbiome studies, we gained insights into gut dysbiosis in AD and MCI. The analysis revealed a decrease in species richness in the AD gut microbiome, region-specific changes in the abundance of Bacteroides, and a significant increase in the Phascolarctobacterium genus during the MCI stage.
Review
Cell Biology
Yi-Jun Ge, Wei Xu, Ya-Nan Ou, Yi Qu, Ya-Hui Ma, Yu-Yuan Huang, Xue-Ning Shen, Shi-Dong Chen, Lan Tan, Qian-Hua Zhao, Jin-Tai Yu
Summary: The study systematically evaluated retinal imaging and electrophysiological markers in patients with Alzheimer's disease, mild cognitive impairment, and preclinical AD. It found that these retinal biomarkers hold great potential for the diagnosis, prognosis, and risk assessment of AD and MCI. Further development of these biomarkers, especially in diagnostic test accuracy and longitudinal studies, is warranted in the future.
AGEING RESEARCH REVIEWS
(2021)
Review
Cell Biology
Helda Pitti, Patricia Diaz-Galvan, Jose Barroso, Atef Badji, Jonas K. Olofsson, Eric Westman, Daniel Ferreira, Nira Cedres
Summary: The study found that subjective cognitive decline may be an early marker of cerebrovascular disease in cognitively healthy individuals, especially in relation to white matter signal abnormalities. Further research is needed to clarify the role of SCD as a preclinical marker of vascular cognitive impairment.
AGEING RESEARCH REVIEWS
(2022)
Review
Clinical Neurology
Guanlin Chen, Xiaoqi Zhou, Yikang Zhu, Wendian Shi, Li Kong
Summary: A comprehensive meta-analysis was conducted to compare gut microbial characteristics in Alzheimer's disease (AD), mild cognitive impairment (MCI), and subjective cognitive decline (SCD). The results showed gut microbiological abnormalities in AD, even as early as the SCD stage. These consistent changes in gut microbes throughout the disease process may serve as potential biomarkers for early identification and diagnosis of AD.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Ho Young Park, Chae Ri Park, Chong Hyun Suh, Woo Hyun Shim, Sang Joon Kim
Summary: Our meta-analysis showed that the medial temporal lobe atrophy (MTA) scale has good diagnostic performance and reliability in patients with Alzheimer's disease.
EUROPEAN RADIOLOGY
(2021)
Article
Medicine, General & Internal
Ewan C. Goligher, Charlotte A. Bradbury, Bryan J. McVerry, Patrick R. Lawler, Jeffrey S. Berger, Michelle N. Gong, Marc Carrier, Harmony R. Reynolds, Anand Kumar, Alexis F. Turgeon, Lucy Z. Kornblith, Susan R. Kahn, John C. Marshall, Keri S. Kim, Brett L. Houston, Lennie P. G. Derde, Mary Cushman, Tobias Tritschler, Derek C. Angus, Lucas C. Godoy, Zoe McQuilten, Bridget-Anne Kirwan, Michael E. Farkouh, Maria M. Brooks, Roger J. Lewis, Lindsay R. Berry, Elizabeth Lorenzi, Anthony C. Gordon, Scott M. Berry, Colin J. McArthur, Matthew D. Neal, Judith S. Hochman, Steven A. Webb, Ryan Zarychanski, Tania Ahuja, Farah Al-Beidh, Djillali Annane, Yaseen M. Arabi, Diptesh Aryal, Lisa Baumann Kreuziger, Abi Beane, Zahra Bhimani, Shailesh Bihari, Henny H. Billett, Lindsay Bond, Marc Bonten, Frank Brunkhorst, Meredith Buxton, Adrian Buzgau, Lana A. Castellucci, Sweta Chekuri, Jen-Ting Chen, Allen C. Cheng, Tamta Chkhikvadze, Benjamin Coiffard, Aira Contreras, Todd W. Costantini, Sophie de Brouwer, Michelle A. Detry, Abhijit Duggal, Vladimir Dzavik, Mark B. Effron, Heather F. Eng, Jorge Escobedo, Lise J. Estcourt, Brendan M. Everett, Dean A. Fergusson, Mark Fitzgerald, Robert A. Fowler, Joshua D. Froess, Zhuxuan Fu, Jean P. Galanaud, Benjamin T. Galen, Sheetal Gandotra, Timothy D. Girard, Andrew L. Goodman, Herman Goossens, Cameron Green, Yonatan Y. Greenstein, Peter L. Gross, Rashan Haniffa, Sheila M. Hegde, Carolyn M. Hendrickson, Alisa M. Higgins, Alexander A. Hindenburg, Aluko A. Hope, James M. Horowitz, Christopher M. Horvat, David T. Huang, Kristin Hudock, Beverley J. Hunt, Mansoor Husain, Robert C. Hyzy, Jeffrey R. Jacobson, Devachandran Jayakumar, Norma M. Keller, Akram Khan, Yuri Kim, Andrei Kindzelski, Andrew J. King, Aaron E. Kornblith, Matthew E. Kutcher, Michael A. Laffan, Francois Lamontagne, Gregoire Le Gal, Christine M. Leeper, Eric S. Leifer, George Lim, Felipe Gallego Lima, Kelsey Linstrum, Edward Litton, Jose Lopez-Sendon, Sylvain A. Lother, Nicole Marten, Andrea Saud Marinez, Mary Martinez, Eduardo Mateos Garcia, Stavroula Mavromichalis, Daniel F. McAuley, Emily G. McDonald, Anna McGlothlin, Shay P. McGuinness, Saskia Middeldorp, Stephanie K. Montgomery, Paul R. Mouncey, Srinivas Murthy, Girish B. Nair, Rahul Nair, Alistair D. Nichol, Jose C. Nicolau, Brenda Nunez-Garcia, John J. Park, Pauline K. Park, Rachael L. Parke, Jane C. Parker, Sam Parnia, Jonathan D. Paul, Mauricio Pompilio, John G. Quigley, Robert S. Rosenson, Natalia S. Rost, Kathryn Rowan, Fernanda O. Santos, Marlene Santos, Mayler O. Santos, Lewis Satterwhite, Christina T. Saunders, Jake Schreiber, Roger E. G. Schutgens, Christopher W. Seymour, Deborah M. Siegal, Delcio G. Silva, Aneesh B. Singhal, Arthur S. Slutsky, Dayna Solvason, Anne M. Turner, Wilma Van Bentum-Puijk, Frank L. van de Veerdonk, Sean van Diepen, Gloria Vazquez-Grande, Lana Wahid, Vanessa Wareham, R. Jay Widmer, Jennifer G. Wilson, Eugene Yuriditsky, Yongqi Zhong
Summary: In critically ill patients with Covid-19, initial therapeutic-dose anticoagulation did not result in improved survival rates or fewer days requiring cardiovascular or respiratory organ support compared to usual-care pharmacologic thromboprophylaxis.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Oncology
Julie M. Cunningham, Stacey J. Winham, Chen Wang, Britta Weiglt, Zhuxuan Fu, Sebastian M. Armasu, Bryan M. McCauley, Alison H. Brand, Yoke-Eng Chiew, Esther Elishaev, Charlie Gourley, Catherine J. Kennedy, Angela Laslavic, Jenny Lester, Anna Piskorz, Magdalena Sekowska, James D. Brenton, Michael Churchman, Anna DeFazio, Ronny Drapkin, Kevin M. Elias, David G. Huntsman, Beth Y. Karlan, Martin Kobel, Jason Konner, Kate Lawrenson, Elli Papaemmanuil, Kelly L. Bolton, Francesmary Modugno, Ellen L. Goode
Summary: This study investigated the role of DNA methylation in ovarian clear cell carcinoma (OCCC). Two clusters that correlated with clinical features were identified. Tumors in Cluster 1 showed TP53 mutation and abnormal p53 expression, while tumors in Cluster 2 showed aneuploidy and ARID1A/PIK3CA mutation. Differentially expressed genes were enriched for immune-related pathways.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Medicine, General & Internal
Jean M. Connors, Maria M. Brooks, Frank C. Sciurba, Jerry A. Krishnan, Joseph R. Bledsoe, Andrei Kindzelski, Amanda L. Baucom, Bridget-Anne Kirwan, Heather Eng, Deborah Martin, Elaine Zaharris, Brendan Everett, Lauren Castro, Nancy L. Shapiro, Janet Y. Lin, Peter C. Hou, Carl J. Pepine, Eileen Handberg, Daniel O. Haight, Jason W. Wilson, Sarah Majercik, Zhuxuan Fu, Yongqi Zhong, Vidya Venugopal, Scott Beach, Steve Wisniewski, Paul M. Ridker
Summary: This study aimed to assess the impact of anticoagulant or antiplatelet therapy on symptomatic clinically stable outpatients with COVID-19. The results showed that treatment with aspirin or apixaban compared with placebo did not reduce the rate of a composite clinical outcome, and the study was terminated early due to a lower than anticipated event rate.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Letter
Hematology
Jean M. Connors, Maria M. Brooks, Frank C. Sciurba, Zhuxuan Fu, Paul M. Ridker
AMERICAN JOURNAL OF HEMATOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Senthil Selvaraj, Zhuxuan Fu, Philip Jones, Lydia C. Kwee, Sheryl L. Windsor, Olga Ilkayeva, Christopher B. Newgard, Kenneth B. Margulies, Mansoor Husain, Silvio E. Inzucchi, Darren K. McGuire, Bertram Pitt, Benjamin M. Scirica, David E. Lanfear, Michael E. Nassif, Ali Javaheri, Robert J. Mentz, Mikhail N. Kosiborod, Svati H. Shah
Summary: This study explored the effects of dapagliflozin on metabolic pathways in HFrEF patients, showing an increase in ketone-related and fatty acid metabolite clusters. It also identified metabolic biomarkers associated with adverse HFrEF outcomes, suggesting a potential role for altered ketone and fatty acid biology with sodium-glucose cotransporter-2 inhibitors.
Review
Oncology
Zhuxuan Fu, Sarah Taylor, Francesmary Modugno
Summary: This study aimed to assess the relationship between lifetime ovulatory years (LOY) and the risk and survival of epithelial ovarian cancer (EOC). The findings suggest that LOY is associated with an increased risk of EOC and specific histotypes of tumors. However, there is limited research on the association between LOY and survival, calling for further studies with larger sample sizes and more accurate data.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Oncology
Kelly L. Bolton, Denise Chen, Rosario Corona de la Fuente, Zhuxuan Fu, Rajmohan Murali, Martin Kobel, Yanis Tazi, Julie M. Cunningham, Irenaeus C. C. Chan, Brian J. Wiley, Lea A. Moukarzel, Stacey J. Winham, Sebastian M. Armasu, Jenny Lester, Esther Elishaev, Angela Laslavic, Catherine J. Kennedy, Anna Piskorz, Magdalena Sekowska, Alison H. Brand, Yoke-Eng Chiew, Paul Pharoah, Kevin M. Elias, Ronny Drapkin, Michael Churchman, Charlie Gourley, Ann DeFazio, Beth Karlan, James D. Brenton, Britta Weigelt, Michael S. Anglesio, David Huntsman, Simon Gayther, Jason Konner, Francesmary Modugno, Kate Lawrenson, Ellen L. Goode, Elli Papaemmanuil
Summary: This study identifies two distinct molecular subclasses of clear cell ovarian carcinoma (CCOC) with different clinical presentations and outcomes. Tumors with ARID1A mutations are associated with platinum resistance, while tumors with TP53 mutations are associated with extracellular matrix organization and mesenchymal differentiation. TP53-mutated tumors are more likely to be advanced-stage, without a history of endometriosis, and have poorer survival.
CLINICAL CANCER RESEARCH
(2022)
Article
Oncology
Nicola S. Meagher, Kylie L. Gorringe, Matthew Wakefield, Adelyn Bolithon, Chi Nam Ignatius Pang, Derek S. Chiu, Michael S. Anglesio, Kylie-Ann Mallitt, Jennifer A. Doherty, Holly R. Harris, Joellen M. Schildkraut, Andrew Berchuck, Kara L. Cushing-Haugen, Ksenia Chezar, Angela Chou, Adeline Tan, Jennifer Alsop, Ellen Barlow, Matthias W. Beckmann, Jessica Boros, David D. L. Bowtell, Alison H. Brand, James D. Brenton, Ian Campbell, Dane Cheasley, Joshua Cohen, Cezary Cybulski, Esther Elishaev, Ramona Erber, Rhonda Farrell, Anna Fischer, Zhuxuan Fu, Blake Gilks, Anthony J. Gill, Charlie Gourley, Marcel Grube, Paul R. Harnett, Arndt Hartmann, Anusha Hettiaratchi, Claus K. Hogdall, Tomasz Huzarski, Anna Jakubowska, Mercedes Jimenez-Linan, Catherine J. Kennedy, Byoung-Gie Kim, Jae-Weon Kim, Jae-Hoon Kim, Kayla Klett, Jennifer M. Koziak, Tiffany Lai, Angela Laslavic, Jenny Lester, Yee Leung, Na Li, Winston Liauw, Belle W. X. Lim, Anna Linder, Jan Lubinski, Sakshi Mahale, Constantina Mateoiu, Simone McInerny, Janusz Menkiszak, Parham Minoo, Suzana Mittelstadt, David Morris, Sandra Orsulic, Sang-Yoon Park, Celeste Leigh Pearce, John Pearson, Malcolm C. Pike, Carmel M. Quinn, Ganendra Raj Mohan, Jianyu Rao, Marjorie J. Riggan, Matthias Ruebner, Stuart Salfinger, Clare L. Scott, Mitul Shah, Helen Steed, Colin J. R. Stewart, Deepak Subramanian, Soseul Sung, Katrina Tang, Paul Timpson, Robyn L. Ward, Rebekka Wiedenhoefer, Heather Thorne, Paul A. Cohen, Philip Crowe, Peter A. Fasching, Jacek Gronwald, Nicholas J. Hawkins, Estrid Hogdall, David G. Huntsman, Paul A. James, Beth Y. Karlan, Linda E. Kelemen, Stefan Kommoss, Gottfried E. Konecny, Francesmary Modugno, Sue K. Park, Annette Staebler, Karin Sundfeldt, Anna H. Wu, Aline Talhouk, Paul D. P. Pharoah, Lyndal Anderson, Anna DeFazio, Martin Kobel, Michael L. Friedlander, Susan J. Ramus
Summary: Clinical and gene expression data were analyzed to identify prognostic and diagnostic features of advanced-stage mucinous ovarian carcinoma (MOC) and differentiate it from gastrointestinal (GI) metastases. An infiltrative growth pattern was associated with poor prognosis, and high expression of THBS2 and TAGLN was linked to adverse prognosis in MOC. HER2 amplification or high mRNA expression was detected in some MOC cases, suggesting the potential of HER2-targeted therapy. MOC samples clustered with upper GI tumors, indicating similar biology and treatment strategies.
CLINICAL CANCER RESEARCH
(2022)
Article
Oncology
Zhuxuan Fu, Maria Mori Brooks, Sarah Irvin, Susan Jordan, Katja K. H. Aben, Hoda Anton-Culver, Elisa Bandera, Matthias W. Beckmann, Andrew Berchuck, Angela Brooks-Wilson, Jenny Chang-Claude, Linda S. Cook, Daniel W. Cramer, Kara L. Cushing-Haugen, Jennifer A. Doherty, Arif B. Ekici, Peter A. Fasching, Renee T. Fortner, Simon A. Gayther, Aleksandra Gentry-Maharaj, Graham G. Giles, Ellen L. Goode, Marc T. Goodman, Holly R. Harris, Alexander Hein, Rudolf Kaaks, Lambertus A. Kiemeney, Martin Koebel, Joanne Kotsopoulos, Nhu D. Le, Alice W. Lee, Keitaro Matsuo, Valerie McGuire, John R. McLaughlin, Usha Menon, Roger L. Milne, Kirsten B. Moysich, Celeste Leigh Pearce, Malcolm C. Pike, Bo Qin, Susan J. Ramus, Marjorie J. Riggan, Joseph H. Rothstein, Joellen M. Schildkraut, Weiva Sieh, Rebecca Sutphen, Kathryn L. Terry, Pamela J. Thompson, Linda Titus, Anne M. van Altena, Emily White, Alice S. Whittemore, Anna H. Wu, Wei Zheng, Argyrios Ziogas, Sarah E. Taylor, Lu Tang, Thomas Songer, Nicolas Wentzensen, Penelope M. Webb, Harvey A. Risch, Francesmary Modugno
Summary: The lifetime ovulatory years (LOY) are positively associated with nonmucinous epithelial ovarian cancer (EOC) risk, implicating factors beyond ovulation in the development of EOC. The protective effects of parity and oral contraceptive use may not solely depend on anovulation.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Infectious Diseases
Joseph Bledsoe, Scott C. Woller, Maria Brooks, Frank C. Sciurba, Jerry A. Krishnan, Deborah Martin, Peter Hou, Janet Y. Lin, Andrei Kindzelski, Eileen Handberg, Bridget-Anne Kirwan, Elaine Zaharris, Lauren Castro, Nancy L. Shapiro, Carl J. Pepine, Sarah Majercik, Zhuxuan Fu, Yongqi Zhong, Vidya Venugopal, Yu-Hsuan Lai, Paul M. Ridker, Jean M. Connors
Summary: A secondary analysis of the ACTIV-4B trial showed that the location of healthcare system engagement is an independent predictor of outcomes in patients with acute stable COVID-19.
BMC INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Ewan C. C. Goligher, Patrick R. R. Lawler, Thomas P. P. Jensen, Victor Talisa, Lindsay R. R. Berry, Elizabeth Lorenzi, Bryan J. J. McVerry, Chung-Chou Ho Chang, Eric Leifer, Charlotte Bradbury, Jeffrey Berger, Beverly J. J. Hunt, Lana A. A. Castellucci, Lucy Z. Kornblith, Anthony C. C. Gordon, Colin McArthur, Steven Webb, Judith Hochman, Matthew D. D. Neal, Ryan Zarychanski, Scott Berry, Derek C. C. Angus
Summary: This study aimed to evaluate the heterogeneity of treatment effect (HTE) of therapeutic-dose heparin in patients hospitalized for COVID-19 and compare different approaches to assessing HTE. The findings showed that the effect of therapeutic-dose heparin varied among patients with different severity levels and BMI, with more benefit observed in less severe or lower BMI patients and more harm in sicker or higher BMI patients.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Nutrition & Dietetics
Hye-Jeong Yang, Min-Jung Kim, Haeng-Jeon Hur, Dai-Ja Jang, Byung-Kook Lee, Myung-Sunny Kim, Sunmin Park
Summary: As the diets and lifestyles of Asians become more westernized, the prevalence of Type 2 diabetes (T2DM) has significantly increased. This study investigated the association between Korean healthy eating index (KHEI) scores and gender-specific T2DM risk in adults. The results showed that high KHEI scores, particularly in the adequacy and balance components, were inversely associated with T2DM risk, but only in women.
Article
Nutrition & Dietetics
Haeng Jeon Hur, Hye Jeong Yang, Min Jung Kim, Kyunhee Lee, Dai Ja Jang, Myung-Sunny Kim, Sunmin Park
Summary: This study examined the interaction between polygenic variants associated with hypo-HDL-C and lifestyle factors in Korean adults, and found that there is an interaction between genetic risk and dietary and smoking habits.
FRONTIERS IN NUTRITION
(2023)
Article
Cardiac & Cardiovascular Systems
Nobuhiro Ikemura, John A. Spertus, Dan D. Nguyen, Takehiro Kimura, Yoshinori Katsumata, Zhuxuan Fu, Philip G. Jones, Nozomi Niimi, Satoshi Shoji, Ikuko Ueda, Kojiro Tanimoto, Masahiro Suzuki, Keiichi Fukuda, Seiji Takatsuki, Shun Kohsaka
Summary: This study aimed to investigate the association between health status and subsequent clinical events among patients with atrial fibrillation (AF).
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Review
Nutrition & Dietetics
Jounghee Lee, Naisi Zhao, Zhuxuan Fu, Jihee Choi, Hae-Jeung Lee, Mei Chung
Summary: A systematic review found that high-dose aged garlic extract was effective in reducing the number and size of colorectal adenomas, but there were inconsistent associations between garlic intake and colorectal cancer risk in cohort studies. Therefore, the current evidence is inadequate to draw a firm conclusion on the effects of garlic on cancer.
NUTRITION RESEARCH AND PRACTICE
(2021)