Review
Medicine, General & Internal
S. Sharif, P. T. Heath, S. J. Oddie, W. McGuire
Summary: The study aims to evaluate the effect of enteral supplementation with synbiotics versus placebo or no treatment, or versus probiotics or prebiotics alone on the risk of necrotising enterocolitis and associated morbidity and mortality in very preterm or very low birth weight infants.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Microbiology
Yong Zhang, Tingting Zheng, Da Ma, Peng Shi, Heping Zhang, Jun Li, Zhihong Sun
Summary: This study investigated the antihypertensive effect of Bifidobacterium lactis M8 and Lactobacillus rhamnosus M9 in high-fructose-treated mice. The results showed that these probiotics significantly reduced blood pressure and were associated with specific gut microbes and metabolic pathways. This study provides a potential mechanistic understanding of probiotics modulated blood pressure and their therapeutic potential in hypertension management.
Article
Food Science & Technology
Joana Charlot Pohlentz, Nicole Gallala, Konrad Kosciow, Marcel Hoevels
Summary: This study investigates the prebiotic properties of inulin- and levan-based fructans and their effects on the gut microbiota. The results showed that the majority of strains isolated from probiotic products or yogurts responded positively to prebiotic treatment. Additionally, the consumption rate of fructans was influenced by their degree of polymerization and specific components.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Food Science & Technology
Florinda Fratianni, Beatrice De Giulio, Antonio d'Acierno, Giuseppe Amato, Vincenzo De Feo, Raffaele Coppola, Filomena Nazzaro
Summary: Honey has beneficial effects on gut health and the immune system. Different types of honey have varying effects on the growth and adhesion of probiotics, as well as the inhibition of pathogenic biofilms.
Review
Food Science & Technology
Parisa Janmohammadi, Zeinab Nourmohammadi, Siavash Fazelian, Atieh Mirzababaei, Shahab Alizadeh, Mahtab Zarei, Elnaz Daneshzad, Kurosh Djafarian
Summary: Several studies have suggested that formulas containing synbiotics (composed of prebiotics and probiotics) may have a positive effect on anthropometric indices. However, the results of these studies are inconsistent. This meta-analysis found that the consumption of formulas containing synbiotics did not significantly affect the growth of healthy infants.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
J. I. Ramirez-Perez, M. Abud-Archila, S. L. Ovando-Chacon, R. E. Soria-Guerra, M. A. Ruiz-Cabrera, C. I. Godinez-Hernandez, A. Grajales-Lagunes
Summary: A completely randomized experimental design was conducted to evaluate the effect of coadministration of Lpb. fabifermentans and inulin/agave fructans mixtures on gut microbiota. The results showed that the combination of fructan mixtures and Lpb. fabifermentans significantly decreased glucose, cholesterol, and triglycerides levels, and improved short-chain fatty acids concentration throughout the gastrointestinal tract. It also promoted an increase in the abundance of beneficial intestinal microbiota. Therefore, the inclusion of fructan mixtures in combination with Lpb. fabifermentans could be a good alternative for the development of functional foods that enhance consumer health.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Nutrition & Dietetics
Neeraj K. Singh, Jeffrey M. Beckett, Krishnakumar Kalpurath, Muhammad Ishaq, Tauseef Ahmad, Rajaraman D. Eri
Summary: Chemotherapy is the primary treatment for cancer patients, but it often leads to complications. Restoring the gut microbiota through the use of probiotics is a potential approach to reduce chemotherapy-associated complications.
Article
Food Science & Technology
Ana K. F. Leite, Brenda N. Santos, Thatyane V. Fonteles, Sueli Rodrigues
Summary: Prebiotic cashew apple juice produced by enzyme synthesis contains oligosaccharides, dextran, and tagatose, which have a promoting effect on the growth of probiotics. Different microorganisms consume different carbohydrates, and when metabolized by beneficial microorganisms in the gut, the prebiotic juice promotes the growth of these probiotics.
Article
Microbiology
Niloofar Akhavan, Katarzyna Hrynkiewicz, Dominika Thiem, Cinzia Randazzo, Ann M. Walsh, Kieran J. Guinan, John T. O'Sullivan, Katarzyna Stadnicka
Summary: The use of probiotics, prebiotics, and synbiotics in poultry diets can promote the health and welfare of the animals by stimulating the growth of gut microbiome. This study analyzed different probiotics and prebiotics to identify the most promising candidates for synbiotic combinations. The results showed that certain prebiotics significantly stimulated the growth of probiotics, with astragalus polysaccharide and vegetable protein hydrolysate being the most effective ones. The strains belonging to L. plantarum (B4), L. rhamnosus (B3), and B. lactis (B2) are considered the best candidates for synbiotic combinations. These findings have implications for future in vivo trials on poultry microbiome modulation.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Nutrition & Dietetics
Ellen Wilms, Ran An, Agnieszka Smolinska, Yala Stevens, Antje R. Weseler, Montserrat Elizalde, Marie-Jose Drittij, Athanasia Ioannou, Frederik J. van Schooten, Hauke Smidt, Ad A. M. Masclee, Erwin G. Zoetendal, Daisy M. A. E. Jonkers
Summary: The study compared the fecal microbiota composition, metabolite production, immune and oxidative stress markers in prefrail elderly and younger adults, and investigated the effects of GOS supplementation in both groups. Results showed differences in microbial composition between the two age groups, with lower bifidobacteria in elderly at baseline. GOS intake increased bifidobacteria in both groups, but did not significantly impact fecal and breath metabolites, immune function, or oxidative stress markers.
CLINICAL NUTRITION
(2021)
Article
Immunology
Carlos Blazquez-Bondia, Mariona Parera, Francesc Catala-Moll, Maria Casadella, Aleix Elizalde-Torrent, Meritxell Aguilo, Jordi Espadaler-Mazo, Jose Ramon Santos, Roger Paredes, Marc Noguera-Julian
Summary: In a clinical trial, a synbiotic intervention was found to have a slight positive effect on immune reconstitution in HIV-1 infected immuno-discordant patients, with a small increase in CD4/CD8 ratio and minor reductions in sCD14. However, a probiotic intervention alone did not show any impact on immune parameters or faecal microbiome composition.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
Loret Keulers, Ali Dehghani, Leon Knippels, Johan Garssen, Nikolaos Papadopoulos, Gert Folkerts, Saskia Braber, Jeroen van Bergenhenegouwen
Summary: Air pollution is a major public health issue, causing an estimated seven million deaths worldwide each year. The exposure to air pollutants, both outdoor and indoor, can lead to gastrointestinal and respiratory impairments and diseases. The gut and lung have a crosstalk called the gut-lung axis, which can be influenced by probiotics, prebiotics, and synbiotics, ultimately affecting gut and lung health.
ENVIRONMENTAL POLLUTION
(2022)
Review
Biochemistry & Molecular Biology
Agnieszka Chlebicz-Wojcik, Katarzyna Slizewska
Summary: Irritable bowel syndrome is not life-threatening but significantly impacts quality of life and economic loss. Research focuses on the role of intestinal microbiota in disease development, with an emphasis on therapies modulating the microbiota such as probiotics, prebiotics, and synbiotics. Most studies have focused on probiotics, but there are also promising results from studies on prebiotics and synbiotics.
Review
Food Science & Technology
Haydee Eliza Romero-Luna, Audry Gustavo Peredo-Lovillo, Maribel Jimenez-Fernandez
Summary: This review gathers information on the studies of microorganisms, especially probiotics, in reducing cholesterol. It is found that probiotics can enhance the reduction of cholesterol with the use of dietary fibers or prebiotics.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Nutrition & Dietetics
Mihaela Cristina Buhas, Laura Ioana Gavrilas, Rares Candrea, Adrian Catinean, Andrei Mocan, Doina Miere, Alexandru Tataru
Summary: Psoriasis is a chronic inflammatory skin disease with autoimmune characteristics, and its pathogenesis is closely related to gut microbiota. Modulation of gut microbiota through dietary approaches or supplementation with probiotics and prebiotics could serve as a novel therapeutic approach for psoriasis.
