Article
Endocrinology & Metabolism
Sara E. Stinson, Anna E. Jonsson, Ierai Fernandez de Retana Alzola, Morten A. Lund, Christine Frithioff-Bojsoe, Louise Aas Holm, Cilius E. Fonvig, Oluf Pedersen, Lars Angquist, Thorkild I. A. Sorensen, Jens J. Holst, Michael Christiansen, Jens-Christian Holm, Bolette Hartmann, Torben Hansen
Summary: Elevated fasting glucagon concentrations in youth with overweight/obesity are associated with worsened cardiometabolic risk outcomes, except for hyperglycemia.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Pediatrics
Tany E. Garciduenas-Fimbres, Indira Paz-Graniel, Carlos Gomez-Martinez, Jose Manuel Jurado-Castro, Rosaura Leis, Joaquin Escribano, Luis A. Moreno, Santiago Navas-Carretero, Olga Portoles, Karla A. Perez-Vega, Mercedes Gil-Campos, Alicia Lopez-Rubio, Cristina Rey-Renones, Pilar De Miguel-Etayo, J. Alfredo Martinez, Katherine Flores-Rojas, Rocio Vazquez-Cobela, Veronica Luque, Maria Luisa Miguel-Berges, Belen Pastor-Villaescusa, Francisco Jesus Llorente-Cantarero, Jordi Salas-Salvado, Nancy Babio
Summary: This study aimed to investigate the associations between eating speed, adiposity, cardiometabolic risk factors, and diet quality in Spanish preschool children. The findings showed that faster eating speed was linked to higher prevalence of overweight/obesity, larger waist circumference, greater fat mass index, higher systolic blood pressure and fasting plasma glucose levels, as well as lower adherence to a Mediterranean diet. Further long-term and interventional studies are needed to confirm these associations.
JOURNAL OF PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Li Ding, Yuxin Fan, Jing He, Ruodan Wang, Qing He, Jingqiu Cui, Zhongshu Ma, Fangqiu Zheng, Hua Gao, Chenlin Dai, Hongyan Wei, Jun Li, Yuming Cao, Gang Hu, Ming Liu
Summary: This study evaluated the impact of adiposity and fat distribution on cardiovascular risk factors in adults with type 2 diabetes mellitus. It found that increased leg fat mass was associated with better glycemic control, while increased android fat mass was linked to higher risks of hypertension. Increasing BMI, trunk-to-leg fat ratio, and android-to-gynoid fat ratio were all significantly associated with elevated risks of cardiovascular risk factors.
Article
Nutrition & Dietetics
Bartosz Hudzik, Justyna Nowak, Janusz Szkodzinski, Barbara Zubelewicz-Szkodzinska
Summary: This study investigated the relationship between visceral adiposity and general adiposity in patients with stable CAD. The results showed correlations between visceral adiposity and nutritional status, as well as body adiposity index. Most patients with normal nutritional status had some form of adipose tissue dysfunction in the viscera. Furthermore, the body mass index performed better in predicting mild and severe visceral adipose tissue dysfunction compared to body adiposity index.
Article
Endocrinology & Metabolism
Carolyn T. Bramante, Elise F. Palzer, Kyle D. Rudser, Justin R. Ryder, Claudia K. Fox, Eric M. Bomberg, Megan O. Bensignor, Amy C. Gross, Nancy E. Sherwood, Aaron S. Kelly
Summary: The study found that %BMIp95 and %BMIp50 were the most strongly correlated with measures of adiposity in youth, while BMIp consistently had the lowest correlations.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Review
Biochemistry & Molecular Biology
Antonella Meloni, Christian Cadeddu, Lucia Cugusi, Maria Pia Donataccio, Martino Deidda, Susanna Sciomer, Sabina Gallina, Cristina Vassalle, Federica Moscucci, Giuseppe Mercuro, Silvia Maffei
Summary: Metabolic syndrome is a clinical condition characterized by the aggregation of major risk factors for cardiovascular disease and type 2 diabetes, including dyslipidemia, high blood pressure, abnormal blood sugar, and abdominal obesity. These risk factors have an independent effect but become synergistic when combined, leading to a doubled risk of cardiovascular diseases and a 1.5-fold increase in all-cause mortality. This article explores gender differences in the epidemiology, etiology, pathophysiology, and clinical expression of metabolic syndrome components, as well as gender differences in new biochemical markers of metabolic syndrome and cardiovascular risk.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Hematology
Sharnendra K. Sidhu, Jose O. Aleman, Sean P. Heffron
Summary: Both the severity and duration of obesity have an impact on cardiovascular disease risk. However, the duration of obesity has been neglected in obesity research. While obesity severity is closely linked to cardiometabolic diseases, the duration of obesity also increases the risk of these diseases.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Environmental Sciences
Jingjing Zhao, Daniel Gomes, Lexiao Jin, Steven P. Mathis, Xiaohong Li, Eric C. Rouchka, Haribabu Bodduluri, Daniel J. Conklin, Timothy E. O'Toole
Summary: Vast amounts of plastic waste are disposed in water systems and landfills, and the ingestion of microplastics may promote cardiovascular disease development, although the health consequences are currently unknown.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Nutrition & Dietetics
Raissa Dias Fernandez, Graziela Maria Benevenuto Bezerra, Lane Viana Krejcova, Daniela Lopes Gomes
Summary: This study evaluated the correlation between anthropometric variables and the quality of life in individuals with Parkinson's disease. The results showed that quality of life was worse in terms of body discomfort, social support, and mobility, and it deteriorated with advanced age. There were also correlations between the worst scores in quality of life dimensions and nutritional status.
Article
Multidisciplinary Sciences
Maria Ruiz-Castell, Hanen Samouda, Valery Bocquet, Guy Fagherazzi, Saverio Stranges, Laetitia Huiart
Summary: The study found a significant association between visceral adiposity and cardiometabolic diseases, with an increased risk of hypertension, prediabetes/diabetes, hypercholesterolemia, and hypertriglyceridemia as visceral adipose tissue increases. Additionally, women had higher odds for all outcomes compared to men except for hypertension, suggesting a gender difference in the impact of visceral adiposity on cardiometabolic health. Future research should explore the effects of changes in visceral adipose tissue on cardiometabolic health and the use of anthropometrically predicted VAT as a reliable outcome measure in the absence of biomedical imaging.
SCIENTIFIC REPORTS
(2021)
Article
Education, Scientific Disciplines
Waleed Albaker, Said El-Ashker, Mohamed A. Baraka, Nagla El-Tanahi, Mohammad Ahsan, Mohammed Al-Hariri
Summary: The study found a high prevalence of overweight and obesity among university students, with males showing higher adiposity and cardiometabolic disease risk. Early prediction of cardiometabolic disease is crucial for preventing health issues related to adiposity, emphasizing the importance of awareness about healthy eating and physical activity.
Article
Pediatrics
Rita Santos-Silva, Manuel Fontoura, Joao T. Guimaraes, Henrique Barros, Ana Cristina Santos
Summary: The study found that there is an association between low birth size and obesity with higher levels of dehydroepiandrosterone sulfate (DHEAS) in childhood. DHEAS levels were positively associated with all adiposity indicators.
PEDIATRIC RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Iwona Swiatkiewicz, Marcin Wroblewski, Jaroslaw Nuszkiewicz, Pawel Sutkowy, Joanna Wroblewska, Alina Wozniak
Summary: Cardiometabolic diseases (CMDs), including cardiovascular disease (CVD), metabolic syndrome (MetS), and type 2 diabetes (T2D), have been associated with increased morbidity and mortality. The imbalances in oxidant-antioxidant levels are largely responsible for the development and outcomes of CMDs. Understanding the relationship between adiposity, oxidative stress, and cardiometabolic risks can help identify new strategies for reducing the burden of CMDs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Neurosciences
Muge Yilmaz, Tutku Atuk Kahraman, Emine Kurtbeyoglu, Nurefsan Konyaligil Ozturk, Murat Gultekin
Summary: This study aimed to evaluate the nutritional status of individuals with Parkinson's disease, finding that GNRI had a lower capability in detecting malnutrition compared to MNA. While there was a positive correlation between MNA and GNRI scores, the correlation was not significant.
NUTRITIONAL NEUROSCIENCE
(2022)
Review
Cardiac & Cardiovascular Systems
Jian-Jun Li, Hui-Hui Liu, Sha Li
Summary: China is facing a cardiovascular disease crisis due to rapid economic growth and changes. The prevalence of cardiometabolic risk factors has increased over the past decades, leading to a rise in deaths from cardiovascular diseases. This narrative review provides an updated overview of the epidemiology of cardiometabolic risk factors in China and discusses strategies to tackle this pandemic. Effective interventions and treatments for these risk factors are also highlighted in this review.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Clinical Neurology
Gianni Pezzoli, Emanuele Cereda, Paolo Amami, Santo Colosimo, Michela Barichella, Giorgio Sacilotto, Anna Zecchinelli, Michela Zini, Valentina Ferri, Carlotta Bolliri, Daniela Calandrella, Maria Grazia Bonelli, Viviana Cereda, Elisa Reali, Serena Caronni, Erica Cassani, Margherita Canesi, Francesca Del Sorbo, Paola Soliveri, Luigi Zecca, Catherine Klersy, Roberto Cilia, Ioannis U. Isaias
Summary: There is evidence suggesting a partial relationship between Parkinson's disease and diabetes. The occurrence of diabetes before the onset of Parkinson's disease delays its onset, while diabetes occurring after the onset of Parkinson's disease has no effect on survival. This study highlights the potential of antidiabetic drugs as a disease-modifying therapy for Parkinson's disease.
JOURNAL OF NEUROLOGY
(2023)
Correction
Endocrinology & Metabolism
Raffaella Cancello, Amelia Brunani, Ettore Brenna, Davide Soranna, Simona Bertoli, Antonella Zambon, Henry C. Lukaski, Paolo Capodaglio
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Article
Endocrinology & Metabolism
Amanda Casirati, Silvia Crotti, Alessandro Raffaele, Riccardo Caccialanza, Emanuele Cereda
Summary: Diseases of the liver and the digestive system can lead to malnutrition and changes in body composition. Phase angle (PhA) is a useful indicator for assessing nutritional status and body composition in patients with inflammatory bowel and liver diseases.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Editorial Material
Nutrition & Dietetics
Amanda Casirati, Valentina Da Prat, Emanuele Cereda, Francesco Serra, Lorenzo Perrone, Salvatore Corallo, Francesco De Lorenzo, Paolo Pedrazzoli, Riccardo Caccialanza
Review
Environmental Sciences
Valentina Martinelli, Simran Singh, Pierluigi Politi, Riccardo Caccialanza, Andrea Peri, Andrea Pietrabissa, Matteo Chiappedi
Summary: Obesity is increasingly common among adolescents. Bariatric surgery (BS) has been shown to be an effective treatment option for severely obese adolescents, but ethical concerns and country disparities regarding this procedure remain. This review focuses on the current ethical challenges of performing BS during adolescence and proposes potential future research directions for ethical and patient-centered management of obesity in adolescents.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Nutrition & Dietetics
Amanda Casirati, Alberto Somaschini, Monica Muraca, Emanuele Cereda, Vera Morsellino, Natascia Di Iorgi, Riccardo Caccialanza, Riccardo Haupt
Summary: This study aimed to evaluate the association between fat-to-lean mass ratio (FLR) and dysmetabolic profile in childhood cancer survivors (CCS). The results showed that CCS with FLR ≥0.6 were more likely to be overweight and obese and had higher levels of triglycerides, insulin resistance, and liver function, while having lower levels of insulin-like growth factor 1 and lean mass. Waist circumference, insulin-like growth factor 1, and trunk fat were independent predictors of FLR ≥0.6. It is important to maintain long-term nutritional status through diet and physical activity.
Article
Health Care Sciences & Services
Gianluca Mauri, Martino Pedrani, Silvia Ghezzi, Katia Bencardino, Sara Mariano, Erica Bonazzina, Francesco Serra, Paolo Pedrazzoli, Riccardo Caccialanza, Giulia Martina Cavestro, Salvatore Siena, Salvatore Artale, Andrea Sartore-Bianchi
Summary: Incidence of early-onset colorectal cancer (EO-CRC) is increasing, posing a clinical challenge. Clinicians tend to treat EO-CRC patients with more intensive regimens despite lack of survival benefits, based on age-related bias. Limited evidence is available regarding treatment-related toxicities in this subset of patients.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2023)
Editorial Material
Oncology
A. Casirati, V. Da Prat, E. Cereda, F. Sebastiani, I. Trestini, L. Perrone, F. Serra, M. Cintoni, P. Pedrazzoli, R. Caccialanza
Review
Nutrition & Dietetics
Sofia Matteucci, Giulia De Pasquale, Manuela Pastore, Emanuela Morenghi, Veronica Pipitone, Fanny Soekeland, Riccardo Caccialanza, Beatrice Mazzoleni, Stefano Mancin
Summary: This study provides an updated analysis on the efficacy of the low-bacterial diet (LBD) in reducing infections, mortality rates, and quality of life in neutropenic patients with cancer. The results show that LBD does not reduce infection and mortality rates and negatively impacts quality of life.
Article
Medicine, General & Internal
Amelia Brunani, Raffaella Cancello, Michele Gobbi, Elisa Lucchetti, Giulia Di Guglielmo, Sabrina Maestrini, Stefania Cattaldo, Paolo Pitera, Chiara Ruocco, Alessandra Milesi, Alessandra Valerio, Paolo Capodaglio, Enzo Nisoli
Summary: This study aimed to assess the impact of protein or amino acid supplements on muscle mass loss in middle-aged men. The results showed that the PD-E07 supplement group had a notable increase in muscle mass compared to the control group, while the protein and BCAA supplement groups did not exhibit a significant difference. Therefore, amino acid-based supplements may effectively mitigate the loss of muscle mass during weight reduction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Oncology
Amanda Casirati, Valentina Da Prat, Arianna Bettiga, Lucia Aretano, Francesco Trevisani, Emanuele Cereda, Alberto Briganti, Elisa Colombo, Giorgia Preziati, Francesca De Simeis, Andrea Salonia, Francesco Montorsi, Riccardo Caccialanza, Richard Naspro
Summary: Preoperative nutritional status is crucial in cancer patients undergoing radical cystectomy, as malnutrition increases the risk of post-surgical complications. Muscle mass loss, a major consequence of cancer-related malnutrition, is associated with readmission, longer hospital stays, and higher mortality rates. Immunonutrition, using specific nutrients to boost the immune system, shows promising evidence in reducing complications after bladder surgery. Further research is needed to determine the optimal approach for improving patient outcomes and establish the effectiveness of perioperative immunonutrition.
Article
Clinical Neurology
Grazia Devigili, Giulia Straccia, Emanuele Cereda, Barbara Garavaglia, Alessandro Fedeli, Antonio Emanuele Elia, Sylvie Helene Marie, Sylvie Helene Marie Jeanne Piacentini, Sara Prioni, Paolo Amami, Federica Invernizzi, Nico Golfre Andreasi, Luigi Michele Romito, Roberto Eleopra, Roberto Cilia
Summary: This study provides instrumental measures of autonomic dysfunction in GBA-PD patients and explores their correlation with non-motor symptoms. It shows that GBA-PD patients have more severe cardiovascular and sudomotor autonomic abnormalities compared to noncarriers, despite minimal clinical correlates. These findings highlight the importance of implementing instrumental autonomic assessment in GBA-PD patients.
MOVEMENT DISORDERS CLINICAL PRACTICE
(2023)
Article
Nutrition & Dietetics
Sarah Maria Barneze Costa, Raghavendra Lakshmana Shetty Hallur, David Rafael Abreu Reyes Postdoc, Juliana Ferreira Floriano Postdoc, Maria Antonieta de Barros Leite Carvalhaes, Helio Rubens de Carvalho Nunes, Luis Sobrevia, Paola Valero, Angelica Mercia Pascon Barbosa, Marilza Cunha Vieira Rudge
Summary: This study aimed to assess maternal dietary intake patterns, anthropometric measures, and biochemical markers in women with gestational diabetes mellitus and pregnancy-specific urinary incontinence. The results showed that pregnant women in the gestational diabetes mellitus pregnancy-specific urinary incontinence group had higher body mass index, arm circumference, and triceps skinfold than the other groups, indicating an obesogenic maternal environment. Significant differences in dietary food intake were also observed. The study emphasizes the need for a comprehensive strategy for pregnant women with gestational diabetes mellitus and pregnancy-specific urinary incontinence to address obesity and micronutrient deficiencies.
Article
Nutrition & Dietetics
Aikaterina Vasileiou, Dominique Searle, Sofus C. Larsen, Faidon Magkos, Graham Horgan, R. James Stubbs, Ines Santos, Antonio L. Palmeira, Berit L. Heitmann
Summary: The study compared self-reported total energy intake with total energy expenditure estimated from Fitbit Charge 2 algorithms. The results showed that self-reported energy intake was generally lower than energy expenditure, and the degree of underestimation varied among different populations.
Article
Nutrition & Dietetics
Ziya Erokay Metin, Ozge Mengi Celik, Nevra Koc
Summary: This study demonstrates a significant relationship between climate change awareness and sustainable and healthy eating behaviors as well as adherence to the Mediterranean diet.
Article
Nutrition & Dietetics
Carolline Santos Miranda, Flavia Maria Silva-Veiga, Daiana Araujo Santana-Oliveira, Isabela Macedo Lopes Vasques-Monteiro, Julio Beltrame Daleprane, Vanessa Souza-Mello
Summary: This study investigates the role of peroxisome proliferator-activated receptor (PPAR) activation on thermogenic pathways and mitochondrial metabolism in mouse adipose tissue. The results show that activation of PPARa and dual PPARa/y can reduce body mass, mitigate insulin resistance, and induce browning in white adipose tissue. Preserved mitochondrial metabolism emerges as a potential target for obesity treatment using PPAR agonists, with possible clinical applications.
Article
Nutrition & Dietetics
Qi Ren, Hao-Fan Wu, Ding-Ye Yu, Feng-Min Zhang, Zi-Le Shen, Guo-Wei Huang, Feng Lin, Wei-Zhe Chen, Zhen Yu
Summary: The study aimed to develop a nomogram incorporating preoperative factors for predicting low skeletal muscle mass index and low skeletal muscle radiodensity. The models were calibrated and assessed for their predictive ability using training and validation cohorts, and the clinical usefulness was evaluated using decision curve analysis.
Article
Nutrition & Dietetics
Ruben Castillo-Ortega, Juan Vega-Vargas, Samuel Duran-Aguero
Summary: This study found that during the COVID-19 pandemic, patients with type 1 diabetes experienced decreased adherence to diabetes care, leading to an increase in HbA1c levels, BMI, impaired linear growth, and more hospitalizations. The shift to telemedicine as the main healthcare service also had significant effects on diabetes management.
Article
Nutrition & Dietetics
Yi-Hsiu Chen, Jung-An Lin, Jiun-Rong Chen, Ya-Ling Chen, Suh-Ching Yang
Summary: Regular nutrition consultations have been shown to have significant effects on reducing cardiovascular disease risk factors, especially for individuals with obesity.
Article
Nutrition & Dietetics
Jacinta Winderlich, Bridget Little, Felix Oberender, Tessa Bollard, Tamara Farrell, Samantha Jenkins, Emma Landorf, Andrea McCall, Jessica Menzies, Katie O. ' Brien, Carla Rowe, Kirsten Sim, Melanie van der Wilk, Jemma Woodgate, Eldho Paul, Andrew A. Udy, Emma J. Ridley
Summary: The study aims to describe nutrition provision in Australian and New Zealand pediatric intensive care units, assess the adequacy of enteral nutrition, and evaluate the methods for estimating energy and protein requirements.
Article
Nutrition & Dietetics
Xi Zhang, Jia-Xin Huang, Meng Tang, Qi Zhang, Li Deng, Chun-Hua Song, Wei Li, Han-Ping Shi, Ming-Hua Cong
Summary: The study found that the modified Controlling Nutritional Status system, which includes C-reactive protein as an inflammatory parameter, is more accurate than the traditional system in predicting the survival of patients with cancer cachexia. High Controlling Nutritional Status and modified Controlling Nutritional Status are both independent risk factors for survival and have a negative impact on survival in patients with advanced-stage cancers, such as esophagogastric and colorectal cancer.
Article
Nutrition & Dietetics
Karolien Dams, Gregory R. A. De Meyer, Rita Jacobs, Tom Schepens, Stany Perkisas, Greta Moorkens, Philippe Jorens
Summary: The study aimed to investigate the development of muscle atrophy in COVID-19 intensive care unit patients and its relationship with hospital outcomes. The results showed that the difference in muscle thickness was linked to the outcome, with the best survival observed in the group with stable muscle thickness.
Article
Nutrition & Dietetics
Bruna Clemente Cota, Mariana de Santis Filgueiras, Patricia Feliciano Pereira, Leidjaira Lopes Juvanhol, Juliana Farias de Novaes
Summary: This study found that higher consumption of ultra-processed food (UPF) and a diet consisting of high proinflammatory foods were associated with the normal-weight obesity (NWO) phenotype in children.
Article
Nutrition & Dietetics
Victor Nogueira da Cruz Silveira, Cleber Lopes Campelo, Antonio Luis Rodrigues da Costa, Patricia Maria Abreu Machado, Ana Karina Teixeira da Cunha Franca, Alcione Miranda dos Santos
Summary: This psychometric study proposed a scale for estimating the consumption of ultra processed foods using item response theory. The study used data from a representative sample of 2515 adolescents aged 18 and 19 from Brazilian Birth Cohorts Consortium. The findings demonstrated that the proposed scale can accurately estimate the consumption of ultra processed foods and is correlated with latent traits related to food consumption.
Article
Nutrition & Dietetics
Dehao Yang, Jiaqi Huang, Jingyu Hu, Minyue Zhang, Haobo Xie, Yilin Chen, Yining Jin, Zerui Jiang, Yanchu Wang, Jinrong Zhu, Xin Lu, Siqi Chen, Yiyun Weng, Guangyong Chen
Summary: This study investigates the association between malnutrition and 6-month outcomes in acute ischemic stroke patients with or without intravenous thrombolysis. The results show a significant association between malnutrition and poor functional outcome.
Article
Nutrition & Dietetics
Ainoa Cristina de Oliveira Candido, Felipe Silva Neves, Vanessa Sequeira Fontes, Adriana Soares Torres Melo, Eliane Rodrigues de Faria, Michele Pereira Netto, Renata Maria Souza Oliveira, George Luiz Lins Machado-Coelho, Ana Paula Carlos Candido
Summary: This study investigated the frequency of breakfast consumption and its associations with the consumption of food at different degrees of industrial processing and with overweight indicators in Brazilian adolescents. The results showed that 20% of adolescents skipped breakfast and 46% of their caloric intake came from ultra-processed foods. Skipping breakfast was associated with increased consumption of ultra-processed foods, higher BMI-for-age, and higher body fat percentage.
