Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation

Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs

(2013) Maja T. Tomicic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Co-ordination of base excision repair and genome stability

(2013) Jason L. Parsons et al.   DNA REPAIR

Mammalian Base Excision Repair: the Forgotten Archangel

(2013) Grigory L. Dianov et al.   NUCLEIC ACIDS RESEARCH

HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer

(2012) Yanbin Liu et al.   CARCINOGENESIS

miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression

(2012) W. Zhang et al.   NEURO-ONCOLOGY

TAp63γ enhances nucleotide excision repair through transcriptional regulation of DNA repair genes

(2011) Juan Liu et al.   DNA REPAIR

Characterization of human DNA polymerase κ promoter in response to benzo[a]pyrene diol epoxide

(2011) Huifang Zhu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

KARP-1 works as a heterodimer with Ku70, but the function of KARP-1 cannot perfectly replace that of Ku80 in DSB repair

(2011) Manabu Koike et al.   EXPERIMENTAL CELL RESEARCH

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas

(2011) Jörg Felsberg et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization of Trex1 Induction by IFN-  in Murine Macrophages

(2011) M. Serra et al.   JOURNAL OF IMMUNOLOGY

ATR Autophosphorylation as a Molecular Switch for Checkpoint Activation

(2011) Shizhou Liu et al.   MOLECULAR CELL

O6-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke

(2011) Markus Christmann et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

(2011) Armin Thalhammer et al.   PLoS One

Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

(2011) M. Bauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of an Adaptive Response Targeting DNA Nonhomologous End Joining and Its Transmission to Bystander Cells

(2010) H. Klammer et al.   CANCER RESEARCH

Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity

(2010) Maja T. Tomicic et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma

(2010) Markus Christmann et al.   INTERNATIONAL JOURNAL OF CANCER

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

(2010) Markus Christmann et al.   NUCLEIC ACIDS RESEARCH

N-Methylpurine DNA Glycosylase Plays a Pivotal Role in the Threshold Response of Ethyl Methanesulfonate–Induced Chromosome Damage

(2010) Zoulikha M. Zaïr et al.   TOXICOLOGICAL SCIENCES

Regulation of DNA Polymerase   by the LMP1 Oncoprotein of EBV through the Nuclear Factor- B Pathway

(2009) N. Faumont et al.   CANCER RESEARCH

TREX1 acts in degrading damaged DNA from drug-treated tumor cells

(2009) Chuan-Jen Wang et al.   DNA REPAIR

Response of human DNA polymerase ι promoter to N-methyl-N′-nitro-N-nitrosoguanidine

(2009) Huifang Zhu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

A Nuclear Poly(ADP-Ribose)-Dependent Signalosome Confers DNA Damage-Induced IκB Kinase Activation

(2009) Michael Stilmann et al.   MOLECULAR CELL

CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response

(2008) Silvia Filippi et al.   EMBO JOURNAL

E2F1 Regulates the Base Excision Repair GeneXRCC1and Promotes DNA Repair

(2008) Dexi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATR-dependent Activation of p38 MAP Kinase Is Responsible for Apoptotic Cell Death in Cells Depleted of Cdc7

(2008) Jun-Sub Im et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

(2008) A. Zaky et al.   NUCLEIC ACIDS RESEARCH

Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2

(2008) H Nakamura et al.   ONCOGENE