A dual switch controls bacterial enhancer-dependent transcription

Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation

(2012) Larry J. Friedman et al.   CELL

Mechanisms of Resistance and Clinical Relevance of Resistance to β-Lactams, Glycopeptides, and Fluoroquinolones

(2012) Louis B. Rice   MAYO CLINIC PROCEEDINGS

Signaling-mediated bacterial persister formation

(2012) Nicole M Vega et al.   Nature Chemical Biology

Coupling AAA protein function to regulated gene expression

(2011) Nicolas Joly et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

New target for inhibition of bacterial RNA polymerase: ‘switch region’

(2011) Aashish Srivastava et al.   CURRENT OPINION IN MICROBIOLOGY

A Critical Role of Downstream RNA Polymerase-Promoter Interactions in the Formation of Initiation Complex

(2011) Vladimir Mekler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity Map of theEscherichia coliRNA Polymerase Bridge Helix

(2011) Milija Jovanovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Bacterial Transcription Initiation: RNA Polymerase - Promoter Binding, Isomerization to Initiation-Competent Open Complexes, and Initiation of RNA Synthesis

(2011) Ruth M. Saecker et al.   JOURNAL OF MOLECULAR BIOLOGY

Probing DNA Binding, DNA Opening, and Assembly of a Downstream Clamp/Jaw inEscherichia coliRNA Polymerase−λPRPromoter Complexes Using Salt and the Physiological Anion Glutamate

(2010) Wayne S. Kontur et al.   BIOCHEMISTRY

The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site

(2010) Audrey Tupin et al.   EMBO JOURNAL

Deletion of Switch 3 Results in an Archaeal RNA Polymerase That Is Defective in Transcript Elongation

(2010) Thomas J. Santangelo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple roles of the RNA polymerase β′ SW2 region in transcription initiation, promoter escape, and RNA elongation

(2010) Danil Pupov et al.   NUCLEIC ACIDS RESEARCH

One-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex

(2010) T. J. Gries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A prehydrolysis state of an AAA+ ATPase supports transcription activation of an enhancer-dependent RNA polymerase

(2010) P. C. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T7 phage protein Gp2 inhibits the Escherichia coli RNA polymerase by antagonizing stable DNA strand separation near the transcription start site

(2010) B. Camara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach

(2010) Natacha Opalka et al.   PLOS BIOLOGY

Lost in Transcription-Inhibition of RNA Polymerase

(2009) Dieter Haebich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structures of RNA polymerase–antibiotic complexes

(2009) Mary X Ho et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Allosteric control of Escherichia coli rRNA promoter complexes by DksA

(2009) S. T. Rutherford et al.   GENES & DEVELOPMENT

Maintenance of RNA-DNA Hybrid Length in Bacterial RNA Polymerases

(2009) Tatyana Kent et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coupling σ Factor Conformation to RNA Polymerase Reorganisation for DNA Melting

(2009) Patricia C. Burrows et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of the conserved phenylalanine in the σ54-interacting GAFTGA motif of bacterial enhancer binding proteins

(2009) Nan Zhang et al.   NUCLEIC ACIDS RESEARCH

The RNA Polymerase “Switch Region” Is a Target for Inhibitors

(2008) Jayanta Mukhopadhyay et al.   CELL

An Intramolecular Route for Coupling ATPase Activity in AAA+Proteins for Transcription Activation

(2008) Nicolas Joly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organization of an Activator-Bound RNA Polymerase Holoenzyme

(2008) Daniel Bose et al.   MOLECULAR CELL

Modus operandi of the bacterial RNA polymerase containing the σ54promoter-specificity factor

(2008) Sivaramesh Wigneshweraraj et al.   MOLECULAR MICROBIOLOGY

Transcription inactivation through local refolding of the RNA polymerase structure

(2008) Georgiy A. Belogurov et al.   NATURE

Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation

(2008) Florian Brueckner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural evolution of multisubunit RNA polymerases

(2008) Finn Werner   TRENDS IN MICROBIOLOGY

Late Steps in the Formation of E. coli RNA Polymerase—λPR Promoter Open Complexes: Characterization of Conformational Changes by Rapid [Perturbant] Upshift Experiments

(2007) Wayne S. Kontur et al.   JOURNAL OF MOLECULAR BIOLOGY