Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol γ

Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia†

(2011) Neli Atanassova et al.   HUMAN MOLECULAR GENETICS

Functional analysis of H. sapiens DNA polymerase γ spacer mutation W748S with and without common variant E1143G

(2010) Eino J.H. Palin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The kinetic and chemical mechanism of high-fidelity DNA polymerases

(2010) Kenneth A. Johnson   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations

(2010) Jeffrey D. Stumpf et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae

(2010) J. D. Stumpf et al.   HUMAN MOLECULAR GENETICS

A cluster of pathogenic mutations in the 3′–5′ exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation

(2010) Karolina Szczepanowska et al.   HUMAN MOLECULAR GENETICS

Role of a GAG Hinge in the Nucleotide-induced Conformational Change Governing Nucleotide Specificity by T7 DNA Polymerase

(2010) Zhinan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single Mutation in Human Mitochondrial DNA Polymerase Pol γA Affects Both Polymerization and Proofreading Activities of Only the Holoenzyme

(2010) Young-Sam Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predicting the contribution of novel POLG mutations to human disease through analysis in yeast model

(2010) Enrico Baruffini et al.   MITOCHONDRION

Mitochondrial DNA depletion syndromes – Many genes, common mechanisms

(2010) Anu Suomalainen et al.   NEUROMUSCULAR DISORDERS

Structural Insight into Processive Human Mitochondrial DNA Synthesis and Disease-Related Polymerase Mutations

(2009) Young-Sam Lee et al.   CELL

Mechanisms of DNA Polymerases

(2009) Anthony J. Berdis   CHEMICAL REVIEWS

Disease Mutations in the Human Mitochondrial DNA Polymerase Thumb Subdomain Impart Severe Defects in Mitochondrial DNA Replication

(2009) Rajesh Kasiviswanathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Each Monomer of the Dimeric Accessory Protein for Human Mitochondrial DNA Polymerase Has a Distinct Role in Conferring Processivity

(2009) Young-Sam Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants

(2009) Enrico Baruffini et al.   MITOCHONDRION

Disruption of Mitochondrial DNA Replication in Drosophila Increases Mitochondrial Fast Axonal Transport In Vivo

(2009) Rehan M. Baqri et al.   PLoS One

DNA polymerase gamma and mitochondrial disease: Understanding the consequence of POLG mutations

(2008) Sherine S.L. Chan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Molecular and clinical genetics of mitochondrial diseases due toPOLGmutations

(2008) Lee-Jun C. Wong et al.   HUMAN MUTATION

Structural Basis for DNA-Hairpin Promoter Recognition by the Bacteriophage N4 Virion RNA Polymerase

(2008) Michael L. Gleghorn et al.   MOLECULAR CELL

X-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase

(2008) Katsuhiko S. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA