Strategies for protein synthetic biology

Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity

(2010) N. D. Taylor et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Engineered Proteins Pull Double Duty

(2010) J. R. Cochran   Science Translational Medicine

Lessons from Structural Genomics

(2009) Thomas C. Terwilliger et al.   Annual Review of Biophysics

Frameworks for Programming Biological Function through RNA Parts and Devices

(2009) Maung Nyan Win et al.   CHEMISTRY & BIOLOGY

Designing New Cellular Signaling Pathways

(2009) Peter M. Pryciak   CHEMISTRY & BIOLOGY

Designing switchable enzymes

(2009) Marc Ostermeier   CURRENT OPINION IN STRUCTURAL BIOLOGY

Long-timescale molecular dynamics simulations of protein structure and function

(2009) John L Klepeis et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bimolecular Fluorescence Complementation Analysis of Inducible Protein Interactions: Effects of Factors Affecting Protein Folding on Fluorescent Protein Fragment Association

(2009) Aaron M. Robida et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamic map of protein interactions in the Escherichia coli chemotaxis pathway

(2009) David Kentner et al.   Molecular Systems Biology

Engineering key components in a synthetic eukaryotic signal transduction pathway

(2009) Mauricio S Antunes et al.   Molecular Systems Biology

Protein sequestration generates a flexible ultrasensitive response in a genetic network

(2009) Nicolas E Buchler et al.   Molecular Systems Biology

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Design Parameters to Control Synthetic Gene Expression in Escherichia coli

(2009) Mark Welch et al.   PLoS One

Rapid Modification of Proteins Using a Rapamycin-Inducible Tobacco Etch Virus Protease System

(2009) Damian J. Williams et al.   PLoS One

Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins

(2009) S. Pechmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein design in biological networks: from manipulating the input to modifying the output

(2009) A. M. Van der Sloot et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Enzyme stabilization by domain insertion into a thermophilic protein

(2009) C.-S. Kim et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Critical assessment of methods of protein structure prediction-Round VIII

(2009) John Moult et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Coding-Sequence Determinants of Gene Expression in Escherichia coli

(2009) G. Kudla et al.   SCIENCE

How Perfect Can Protein Interactomes Be?

(2009) E. D. Levy et al.   Science Signaling

Cell regulation: determined to signal discrete cooperation

(2009) Toby J. Gibson   TRENDS IN BIOCHEMICAL SCIENCES

Scaffolds: interaction platforms for cellular signalling circuits

(2009) András Zeke et al.   TRENDS IN CELL BIOLOGY

Measuring the activity of BioBrick promoters using an in vivo reference standard

(2009) Jason R Kelly et al.   Journal of Biological Engineering

A review of biosensors and biologically-inspired systems for explosives detection

(2008) Richard G. Smith et al.   ANALYST

Membrane Localization of Scaffold Proteins Promotes Graded Signaling in the Yeast MAP Kinase Cascade

(2008) Satoe Takahashi et al.   CURRENT BIOLOGY

Advances in laboratory evolution of enzymes

(2008) Shimon Bershtein et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Multiscale methods for macromolecular simulations

(2008) Paul Sherwood et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Flexible ligand docking to multiple receptor conformations: a practical alternative

(2008) Maxim Totrov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Recent Progress and Future Directions in Protein-Protein Docking

(2008) David Ritchie   CURRENT PROTEIN & PEPTIDE SCIENCE

Understanding eukaryotic linear motifs and their role in cell signaling and regulation

(2008) Francesca Diella   Frontiers in Bioscience-Landmark

Enhancement of Cell Type Specificity by Quantitative Modulation of a Chimeric Ligand

(2008) Pablo Cironi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Designed Armadillo Repeat Proteins as General Peptide-Binding Scaffolds: Consensus Design and Computational Optimization of the Hydrophobic Core

(2008) Fabio Parmeggiani et al.   JOURNAL OF MOLECULAR BIOLOGY

Design and Signaling Mechanism of Light-Regulated Histidine Kinases

(2008) Andreas Möglich et al.   JOURNAL OF MOLECULAR BIOLOGY

The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes

(2008) Hirohito Haruki et al.   MOLECULAR CELL

Recursive construction of perfect DNA molecules from imperfect oligonucleotides

(2008) Gregory Linshiz et al.   Molecular Systems Biology

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

Refinement and standardization of synthetic biological parts and devices

(2008) Barry Canton et al.   NATURE BIOTECHNOLOGY

Protein production and purification

(2008) Susanne Gräslund et al.   NATURE METHODS

Linking the functions of unrelated proteins using a novel directed evolution domain insertion method

(2008) Wayne R. Edwards et al.   NUCLEIC ACIDS RESEARCH

Synthetic Activation of Endogenous PI3K and Rac Identifies an AND-Gate Switch for Cell Polarization and Migration

(2008) Takanari Inoue et al.   PLoS One

Light-activated DNA binding in a designed allosteric protein

(2008) D. Strickland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

(2008) C. J. Bashor et al.   SCIENCE

Visualizing cells at the nanoscale

(2008) Andrew Leis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Engineering BioBrick vectors from BioBrick parts

(2008) Reshma P Shetty et al.   Journal of Biological Engineering