A comparative study of short- and long-TE1H MRS at 3 T forin vivodetection of 2-hydroxyglutarate in brain tumors

Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo

(2012) Isaac Marin-Valencia et al.   Cell Metabolism

IDH mutation impairs histone demethylation and results in a block to cell differentiation

(2012) Chao Lu et al.   NATURE

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

(2012) Changho Choi et al.   NATURE MEDICINE

Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy

(2012) O. C. Andronesi et al.   Science Translational Medicine

Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas

(2012) A. Elkhaled et al.   Science Translational Medicine

Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo

(2012) Janeta Popovici-Muller et al.   ACS Medicinal Chemistry Letters

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

(2011) Whitney B. Pope et al.   JOURNAL OF NEURO-ONCOLOGY

If J doesn't evolve, it won't J-resolve: J-PRESS with bandwidth-limited refocusing pulses

(2011) Richard A. E. Edden et al.   MAGNETIC RESONANCE IN MEDICINE

T2 measurement of J-coupled metabolites in the human brain at 3T

(2011) Sandeep K. Ganji et al.   NMR IN BIOMEDICINE

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Slice-selective FID acquisition, localized by outer volume suppression (FIDLOVS) for1H-MRSI of the human brain at 7 T with minimal signal loss

(2009) Anke Henning et al.   NMR IN BIOMEDICINE

Numerical simulations of localized high field 1H MR spectroscopy

(2008) Lana G. Kaiser et al.   JOURNAL OF MAGNETIC RESONANCE

Comparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites

(2008) Paul Gerald Mullins et al.   MAGNETIC RESONANCE IN MEDICINE

Determination of metabolite concentrations in human brain tumour biopsy samples using HR-MAS and ERETIC measurements

(2008) M. Carmen Martínez-Bisbal et al.   NMR IN BIOMEDICINE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE