Article
Genetics & Heredity
Elena I. Zavala, Jacqueline Tyler Thomas, Kimberly Sturk-Andreaggi, Jennifer Daniels-Higginbotham, Kerriann K. Meyers, Suzanne Barrit-Ross, Ayinuer Aximu-Petri, Julia Richter, Birgit Nickel, Gregory E. Berg, Timothy P. McMahon, Matthias Meyer, Charla Marshall
Summary: Applying ancient DNA extraction and library preparation methods to the identification of military remains can improve the success rate of DNA profiling and increase the likelihood of identifying historical skeletons.
Article
Chemistry, Multidisciplinary
Lin Bai, Guojian Yang, Zhaoyu Qin, Jiacheng Lyu, Yunzhi Wang, Jinwen Feng, Mingwei Liu, Tongqing Gong, Xianju Li, Zhengyang Li, Jixi Li, Jun Qin, Wenjun Yang, Chen Ding
Summary: This study used a novel method to analyze the binding activity of transcription factors under DNA modifications and identified potential readers for 5fC-modified DNA. By quantifying the modified DNA-binding activity of 1039 TFs, it revealed the hierarchical networks between the transcriptional protein machinery and modified DNA.
Article
Ethics
Saulius Geniusas
Summary: The paper aims to clarify the importance of Husserl's reflections on destiny in his post-WWI ethics. It examines Husserl's views on war in his private correspondence, and explores how he conceptualized meaningless suffering as destiny in his research manuscripts. The paper shows that Husserl's reflections on the possibility of ethical life in a senseless world led him to deformalize his earlier ethics and ground it in love.
Article
Biochemistry & Molecular Biology
Raffael Siano, Malwenn Lassudrie, Pierre Cuzin, Nicolas Briant, Veronique Loizeau, Sabine Schmidt, Axel Ehrhold, Kenneth Neil Mertens, Clement Lambert, Laure Quintric, Cyril Noel, Marie Latimier, Julien Quere, Patrick Durand, Aurelie Penaud
Summary: This study used sediment cores collected from different sites in the Bay of Brest, northeast Atlantic, France, to retrospectively analyze the effects of human pollution on marine protists over approximately 1,400 years. The research found significant shifts in protist communities after war and agricultural pollution events, with no recovery to a Middle Ages baseline composition, highlighting the irreversible impact of human contaminations on marine microbial compartments.
Article
Economics
Victor Gay
Summary: The high death toll of World War I led to a demographic shock that encouraged many women to enter the labor force immediately after the war. The author provides evidence for a positive impact of these newly employed women on the subsequent generations of women's labor force participation, which still persists today. The study also finds that the war permanently changed attitudes towards women's role in the labor force, and identifies three channels of intergenerational transmission: transmission from mothers to daughters, transmission from mothers-in-law to daughters-in-law through their sons, and transmission through local social interactions.
Article
Economics
Jose A. Lopez, Kris James Mitchener
Summary: After World War I, some European countries experienced hyperinflation due to economic policy uncertainty, driven by political negotiations over reparations payments, debt apportionments, and border disputes. This uncertainty caused a rise in inflation for a few months afterwards in these countries, while other European countries with lower uncertainty levels were better able to implement credible fiscal and monetary policies.
Article
Economics
Roy E. Bailey, Timothy J. Hatton, Kris Inwood
Summary: This article estimates the factors associated with death and injury in action during the First World War for a sample of 2400 nonofficer British servicemen born in the 1890s. The results show that 13.1% of the soldiers were killed in action and another 23.5% were wounded. The probability of death or wounding increases with time in the army and is higher among infantrymen. The article also examines the hypothesis that death and injury were more likely for soldiers from higher socioeconomic backgrounds, but this selectivity is evident among officers rather than ordinary soldiers who comprised 95% of the army.
ECONOMICS & HUMAN BIOLOGY
(2023)
Review
Plant Sciences
Dolores Rita Agius, Aliki Kapazoglou, Evangelia Avramidou, Miroslav Baranek, Elena Carneros, Elena Caro, Stefano Castiglione, Angela Cicatelli, Aleksandra Radanovic, Jean-Paul Ebejer, Daniel Gackowski, Francesco Guarino, Andrea Gulyas, Norbert Hidvegi, Hans Hoenicka, Vera Inacio, Frank Johannes, Erna Karalija, Michal Lieberman-Lazarovich, Federico Martinelli, Stephane Maury, Velimir Mladenov, Leonor Morais-Cecilio, Ales Pecinka, Eleni Tani, Pilar S. Testillano, Dimitar Todorov, Luis Valledor, Valya Vassileva
Summary: Epigenetic modifications, particularly DNA methylation, play a crucial role in preserving genome integrity and regulating gene expression, impacting growth, development, and stress response in plants. Detecting DNA methylation marks is essential for understanding these processes and enhancing crop productivity and stress resistance. This review provides an overview of different methods for detecting plant DNA methylation and compares their efficacy between model and crop plants. It also highlights the strengths and limitations of each method and emphasizes the importance of considering technical and biological factors. Overall, this review will assist scientists in selecting an appropriate DNA methylation profiling method.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Cell Biology
Devasahayam Arokia Balaya Rex, Yashwanth Subbannayya, Prashant Kumar Modi, Akhina Palollathil, Lathika Gopalakrishnan, Yashodhar P. Bhandary, Thottethodi Subrahmanya Keshava Prasad, Sneha M. Pinto
Summary: Interleukin-33 (IL-33) is an important cytokine involved in innate and adaptive immune responses. Aberrant IL-33 signaling has been shown to play a defensive role in infectious and inflammatory diseases. This study used quantitative phosphoproteomics analysis to investigate the temporal signaling dynamics of IL-33 in THP-1 monocytes, and identified differentially regulated proteins and pathways involved in IL-33 signaling.
Article
Economics
Jorn Boehnke, Victor Gay
Summary: This study uses spatial variation in World War I military fatalities in France to demonstrate that the scarcity of men during the war led to an increase in female labor force participation that persisted in the post-war period. Available data suggest that the increase in female labor supply explains this result, with deteriorated marriage market conditions and negative income shocks affecting single women and war widows being the key factors.
JOURNAL OF HUMAN RESOURCES
(2022)
Article
Medicine, General & Internal
Wei Guo, Xin Chen, Rui Liu, Naixin Liang, Qianli Ma, Hua Bao, Xiuxiu Xu, Xue Wu, Shanshan Yang, Yang Shao, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Summary: A predictive model based on cfDNA fragmentomics was developed for early-stage lung adenocarcinoma (LUAD) detection. The model showed high sensitivity for early lesions and small-sized tumors and remained effective even with reduced sequencing depth.
Article
Economics
Sarah Quincy
Summary: This paper explores how a one-time income shock can affect the household wealth distribution through local housing market channels. Using the example of a large income transfer given to World War I veterans by the United States government in 1936, the study finds that this payment significantly improved the recipients' home values and homeownership rates. The impact was more pronounced in areas with higher spatial intensity of the shock, but only for potential home purchasers. Loan-level data suggests that the combination of direct benefits and negative neighborhood spillovers could be attributed to veterans crowding out other potential borrowers.
JOURNAL OF URBAN ECONOMICS
(2022)
Article
Area Studies
Anne Samson
Summary: Africa's involvement in World War I presents unique challenges for researchers, with some depending on limited and outdated publications for their understanding of the conflict. However, a new wave of researchers accessing archival material are breaking new ground and offering fresh insights into Africa's contributions to the War. This diversity of perspectives is reshaping the narrative of Africa's involvement in World War I.
JOURNAL OF ASIAN AND AFRICAN STUDIES
(2022)
Article
Business
Stephanie Seketa
Summary: Beginning in the late 19th century, British companies relied on transnational business networks, but tensions arising from World War I led to movements promoting economic protectionism and consumer nationalism. Entrepreneurs faced scrutiny and took various approaches to manage the hostile environment, including defining their products and services as British in defense against attacks on their citizenship and loyalty.
ENTERPRISE & SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Xiaoqing Yuan, Hong Wang, Shuyi Song, Lili Qiu, Xianming Lan, Pingping Dong, Jiayu Zhang
Summary: This study systematically elucidated the metabolic pathways of Xanthohumol (XN) after oral administration to rats using UHPLC-Q-Exactive Orbitrap MS. A stepwise targeted matching strategy was proposed for the identification of XN metabolites. The results provided essential data for further pharmaceutical studies and laid the foundation for toxicity and safety studies.
Article
Ethics
Jackie Leach Scully
Article
Obstetrics & Gynecology
Jackie Leach Scully, Sarah Banks, Robert Song, Jackie Haq
Article
Ethics
M. A. Verkerk, Hilde Lindemann, Janice McLaughlin, Jackie Leach Scully, Ulrik Kihlbom, Jamie Nelson, Jacqueline Chin
JOURNAL OF MEDICAL ETHICS
(2015)
Editorial Material
Biotechnology & Applied Microbiology
Jackie Leach Scully, Robin Williams
NEW GENETICS AND SOCIETY
(2014)
Article
Ethics
Jackie Leach Scully
Editorial Material
Ethics
Heather Draper, Greg Moorlock, Wendy Rogers, Jackie Leach Scully
Letter
Medicine, General & Internal
Ayesha Ahmad, Ryoa Chung, Lisa Eckenwiler, Agomoni Ganguli-Mitra, Matthew Hunt, Rebecca Richards, Yashar Saghai, Lisa Schwartz, Jackie Leach Scully, Verina Wild
Article
Ethics
Laura Guidry-Grimes, Katie Savin, Joseph A. Stramondo, Joel Michael Reynolds, Marina Tsaplina, Teresa Blankmeyer Burke, Angela Ballantyne, Eva Feder Kittay, Devan Stahl, Jackie Leach Scully, Rosemarie Garland-Thomson, Anita Tarzian, Doron Dorfman, Joseph J. Fins
HASTINGS CENTER REPORT
(2020)
Article
Ethics
Jackie Leach Scully
JOURNAL OF BIOETHICAL INQUIRY
(2020)
Review
Ethics
Yves Saint James Aquino, Wendy A. Rogers, Jackie Leach Scully, Farah Magrabi, Stacy M. Carter
Summary: This article critically compares guidelines for allocating scarce resources during the COVID-19 pandemic, finding that most guidelines primarily use consequentialist reasoning in decision-making with a pluralistic approach. While medical and social criteria are considered, challenges exist in reconciling competing criteria, internal contradictions within guidelines, and use of naive objectivism in applying medical criteria for allocation.
HEALTH CARE ANALYSIS
(2022)
Article
Ethics
Jackie Leach Scully
Summary: This commentary discusses the application of the concept of liminality in the trajectory of cancer survivorship, as well as its exploration of the difficulties experienced by individuals with severe and chronic illnesses during therapeutic interventions. The author also examines the expanding application of this concept to a wider range of medical conditions and the consequences of therapeutic interventions, and discusses how it has enriched and challenged its use as a conceptual tool.
JOURNAL OF BIOETHICAL INQUIRY
(2022)
Review
Genetics & Heredity
Christina Q. Nguyen, Kristine Alba-Concepcion, Elizabeth E. Palmer, Jackie L. Scully, Nicole Millis, Michelle A. Farrar
Summary: The patient voice is increasingly influential in therapeutic innovation, with genomic technologies enabling novel breakthroughs that give renewed hope to rare disease patient organizations. Partnerships between researchers and advocates have reached a critical point, with stakeholders evaluating achievements and planning for future refinement. RDPOs face ethical and financial challenges in advocating for rare diseases, with increasing emphasis on biomedical venture philanthropy and the need for sustainable funding.
ORPHANET JOURNAL OF RARE DISEASES
(2022)
Article
Rehabilitation
Georgia van Toorn, Jackie Leach Scully
Summary: This research examines disabled people's concerns about the use of computer-based tools for assessing eligibility for public disability programs. It recommends a more contextual and experiential approach to assessment to avoid harm to disabled people.
DISABILITY & SOCIETY
(2023)
Article
Ethics
Jackie Leach Scully
INTERNATIONAL JOURNAL OF FEMINIST APPROACHES TO BIOETHICS
(2018)