标题
Death by a Thousand Cuts in Alzheimer’s Disease: Hypoxia—The Prodrome
作者
关键词
Sleep apnea, Chronic intermittent hypoxia, Hypertension, Hypoperfusion, Oxidative stress, Excitotoxicity, Neuronal degeneration
出版物
NEUROTOXICITY RESEARCH
Volume 24, Issue 2, Pages 216-243
出版商
Springer Nature
发表日期
2013-02-11
DOI
10.1007/s12640-013-9379-2
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Conversion of Elderly to Alzheimer's Dementia: Role of Confluence of Hypothermia and Senescent Stigmata – the Plausible Pathway
- (2017) Mak Adam Daulatzai JOURNAL OF ALZHEIMERS DISEASE
- Cerebrovascular Hypoperfusion Induces Spatial Memory Impairment, Synaptic Changes, and Amyloid-β Oligomerization in Rats
- (2017) Xiaojuan Wang et al. JOURNAL OF ALZHEIMERS DISEASE
- Early Stages of Pathogenesis in Memory Impairment during Normal Senescence and Alzheimer's Disease
- (2017) Mak Adam Daulatzai JOURNAL OF ALZHEIMERS DISEASE
- Reduced Brain Gray Matter Concentration in Patients With Obstructive Sleep Apnea Syndrome
- (2017) Eun Yeon Joo et al. SLEEP
- Nocturnal Cerebral Hemodynamics in Snorers and in Patients with Obstructive Sleep Apnea: A Near-Infrared Spectroscopy Study
- (2017) Fabio Pizza et al. SLEEP
- Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress
- (2013) Hyun Ah Kim et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Hypertension and longitudinal changes in cerebral blood flow: The SMART-MR study
- (2012) Majon Muller et al. ANNALS OF NEUROLOGY
- Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias
- (2012) M. Yarchoan et al. BRAIN
- Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease
- (2012) Francesc X. Guix et al. EMBO Molecular Medicine
- Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury
- (2012) Edward D. Hall et al. EXPERIMENTAL NEUROLOGY
- Association Between Ambulatory 24-Hour Blood Pressure Levels and Brain Volume Reduction
- (2012) Sébastien Celle et al. HYPERTENSION
- Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension
- (2012) Stephan C Schäfer et al. HYPERTENSION RESEARCH
- Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-β at Nanomolar Concentrations Is Modulated by Insulin-dependent Akt-GSK3β Signaling Pathway
- (2012) Takayoshi Tokutake et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Obstructive sleep apnea linked to wake-up strokes
- (2012) Sun-Wung Hsieh et al. JOURNAL OF NEUROLOGY
- Central Cardiovascular Circuits Contribute to the Neurovascular Dysfunction in Angiotensin II Hypertension
- (2012) C. Capone et al. JOURNAL OF NEUROSCIENCE
- Severe impairment of circadian rhythm in Alzheimer’s disease
- (2012) Ladislav Volicer et al. Journal of Nutrition Health & Aging
- Midlife vascular risk factors and their association with dementia deaths: Results from a Norwegian prospective study followed up for 35years
- (2012) Bjørn Heine Strand et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer’s disease neuropathology in APPSwe/PS1A246E transgenic mice
- (2012) Xin Zhang et al. NEUROBIOLOGY OF AGING
- Quintessential Risk Factors: Their Role in Promoting Cognitive Dysfunction and Alzheimer’s Disease
- (2012) Mak Adam Daulatzai NEUROCHEMICAL RESEARCH
- Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation
- (2012) R. A. Rissman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The complex contribution of NOS interneurons in the physiology of cerebrovascular regulation
- (2012) Sonia Duchemin et al. Frontiers in Neural Circuits
- Sympathetic and Catecholaminergic Alterations in Sleep Apnea with Particular Emphasis on Children
- (2012) Fahed Hakim et al. Frontiers in Neurology
- Effect of mild hyperglycemia on autonomic function in obstructive sleep apnea
- (2011) Amanda C. Peltier et al. CLINICAL AUTONOMIC RESEARCH
- Obstructive sleep apnoea and metabolic impairment in severe obesity
- (2011) M. Gasa et al. EUROPEAN RESPIRATORY JOURNAL
- Metabolic Control of Resting Hemispheric Cerebral Blood Flow is Oxidative, not Glycolytic
- (2011) William J Powers et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Association between plasma homocysteine levels and obstructive sleep apnoea in patients with ischaemic stroke
- (2011) Maogang Chen et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Hypoxia-Induced Cellular and Vascular Changes in the Nucleus Tractus Solitarius and Ventrolateral Medulla
- (2011) Charanjit Kaur et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Relationship between sleep-disordered breathing and markers of systemic inflammation in women from the general population
- (2011) MALIN SVENSSON et al. JOURNAL OF SLEEP RESEARCH
- Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons
- (2011) Jessica B.S. Langbaum et al. NEUROBIOLOGY OF AGING
- Amyloid-β Production: Major Link Between Oxidative Stress and BACE1
- (2011) Elena Tamagno et al. NEUROTOXICITY RESEARCH
- Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
- (2011) K. J. Anstey et al. Obesity Reviews
- The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice
- (2011) Mahito Yamada et al. PLoS One
- Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea
- (2011) Deepti Nair et al. PLoS One
- FDA-Approved Drugs that Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity
- (2011) Alex Lublin et al. PLoS One
- Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells
- (2011) Katrin J. Svensson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microvascular Endothelial Dysfunction in Obstructive Sleep Apnea Is Caused by Oxidative Stress and Improved by Continuous Positive Airway Pressure Therapy
- (2011) Nikolaus J. Büchner et al. RESPIRATION
- Treatment of obstructive sleep apnea reduces arterial stiffness
- (2011) Nikolaus J. Buchner et al. Sleep and Breathing
- Increased systemic inflammation overnight correlates with insulin resistance among children evaluated for obstructive sleep apnea
- (2011) Mark D. DeBoer et al. Sleep and Breathing
- Impaired cerebral vasoreactivity may cause cerebral blood volume dip following obstructive sleep apnea termination
- (2011) Jaakko Virtanen et al. Sleep and Breathing
- The relationship between high-sensitivity C-reactive protein levels and the severity of obstructive sleep apnea
- (2011) Selma Firat Guven et al. Sleep and Breathing
- Immunohistochemical and histomorphometric study of human uvula innervation: a comparative analysis of non-snorers versus apneic snorers
- (2011) Mauro De Bellis et al. Sleep and Breathing
- Obstructive sleep apnea syndrome is associated with some components of metabolic syndrome in nonobese adults
- (2011) Qi-Chang Lin et al. Sleep and Breathing
- Increased serum levels of advanced glycation end-products is associated with severity of sleep disordered breathing but not insulin sensitivity in non-diabetic men with obstructive sleep apnoea
- (2011) Jamie C.M. Lam et al. SLEEP MEDICINE
- Synergistic Memory Impairment Through the Interaction of Chronic Cerebral Hypoperfusion and Amlyloid Toxicity in a Rat Model
- (2011) Bo-Ryoung Choi et al. STROKE
- Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same Coin
- (2011) Michela Guglielmotto et al. TheScientificWorldJOURNAL
- Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β
- (2010) Maya A. Koike et al. AMERICAN JOURNAL OF PATHOLOGY
- Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction
- (2010) Robert M. Douglas et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Endothelial Dysfunction in the Microcirculation of Patients with Obstructive Sleep Apnea
- (2010) Brian T. Patt et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Obstructive Sleep Apnea: Brain Structural Changes and Neurocognitive Function before and after Treatment
- (2010) Nicola Canessa et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Metabolic consequences of intermittent hypoxia: Relevance to obstructive sleep apnea
- (2010) Luciano F. Drager et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Vascular Inflammation in Obesity and Sleep Apnea
- (2010) Sanja Jelic et al. CIRCULATION
- Antihypertensive therapy for patients with obstructive sleep apnea
- (2010) Michael G Ziegler et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Sleep disorders in neurodegenerative diseases
- (2010) A. Raggi et al. EUROPEAN JOURNAL OF NEUROLOGY
- Increased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea
- (2010) R. J. Kimoff et al. EUROPEAN RESPIRATORY JOURNAL
- Cerebral glucose metabolism in preclinical and prodromal Alzheimer’s disease
- (2010) Karl Herholz Expert Review of Neurotherapeutics
- Intermittent Hypoxia Increases Arterial Blood Pressure in Humans Through a Renin-Angiotensin System-Dependent Mechanism
- (2010) Glen E. Foster et al. HYPERTENSION
- Ectopic Overexpression of Orexin Alters Sleep/Wakefulness States and Muscle Tone Regulation during REM Sleep in Mice
- (2010) Jon T. Willie et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Executive function in patients with obstructive sleep apnea treated with continuous positive airway pressure
- (2010) ESTHER YUET YING LAU et al. JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
- Apnea produces neuronal degeneration in the pons and medulla of guinea pigs
- (2010) Jian-Hua Zhang et al. NEUROBIOLOGY OF DISEASE
- Cognitive profile and brain morphological changes in obstructive sleep apnea
- (2010) Federico Torelli et al. NEUROIMAGE
- Acute hypoxia promote the phosphorylation of tau via ERK pathway
- (2010) Hui Fang et al. NEUROSCIENCE LETTERS
- Chronic cerebral hypoperfusion in a mouse model of Alzheimer's disease: An additional contributing factor of cognitive impairment
- (2010) Jin Soo Lee et al. NEUROSCIENCE LETTERS
- Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease
- (2010) Hyun-Sub Um et al. NEUROSCIENCE RESEARCH
- Vascular basis for brain degeneration: faltering controls and risk factors for dementia
- (2010) Raj N Kalaria NUTRITION REVIEWS
- Nitric oxide and oxidative stress in vascular disease
- (2010) Ulrich Förstermann PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Pathophysiology of Sleep Apnea
- (2010) Jerome A. Dempsey et al. PHYSIOLOGICAL REVIEWS
- Differences in left ventricular cardiomyocyte loss induced by chronic intermittent hypoxia between spontaneously hypertensive and Wistar–Kyoto rats
- (2010) Tsung-I Chen et al. Sleep and Breathing
- Does CPAP treatment in mild obstructive sleep apnea affect blood pressure?
- (2010) Nattapong Jaimchariyatam et al. SLEEP MEDICINE
- NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets
- (2009) Kathleen E. Dennis et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness?
- (2009) Damian M. Bailey et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Hypoxia and Neurodegeneration
- (2009) Chris Peers et al. Annals of the New York Academy of Sciences
- Mediterranean Diet and Mild Cognitive Impairment
- (2009) Nikolaos Scarmeas et al. ARCHIVES OF NEUROLOGY
- Midlife and Late-Life Obesity and the Risk of Dementia
- (2009) Annette L. Fitzpatrick et al. ARCHIVES OF NEUROLOGY
- Chronic cerebral hypoperfusion accelerates amyloid β deposition in APPSwInd transgenic mice
- (2009) Hiroshi Kitaguchi et al. BRAIN RESEARCH
- Contribution of hypoxia to Alzheimer’s disease: is HIF-1α a mediator of neurodegeneration?
- (2009) O. O. Ogunshola et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sympathoadrenal mechanisms in the pathogenesis of sleep apnea-related hypertension
- (2009) Oded Friedman et al. CURRENT HYPERTENSION REPORTS
- The influence of nocturnal alcohol ingestion on snoring
- (2009) Randolf Riemann et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Executive Dysfunction in Patients with Obstructive Sleep Apnea Syndrome
- (2009) Tiia Saunamäki et al. EUROPEAN NEUROLOGY
- Pathological role of hypoxia in Alzheimer's disease
- (2009) Xin Zhang et al. EXPERIMENTAL NEUROLOGY
- Calcium dyshomeostasis and neurotoxicity of Alzheimer’s β-amyloid protein
- (2009) Masahiro Kawahara et al. Expert Review of Neurotherapeutics
- Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer’s disease
- (2009) Magali Dumont et al. FASEB JOURNAL
- Repression of tau hyperphosphorylation by chronic endurance exercise in aged transgenic mouse model of tauopathies
- (2009) Yea-Hyun Leem et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Cardiovascular and cerebrovascular responses to acute hypoxia following exposure to intermittent hypoxia in healthy humans
- (2009) Glen E. Foster et al. JOURNAL OF PHYSIOLOGY-LONDON
- A combined neuropsychological and brain imaging study of obstructive sleep apnea
- (2009) KHALID YAOUHI et al. JOURNAL OF SLEEP RESEARCH
- Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
- (2009) Peter Rosenberger et al. NATURE IMMUNOLOGY
- Effects of poor and short sleep on glucose metabolism and obesity risk
- (2009) Karine Spiegel et al. Nature Reviews Endocrinology
- Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
- (2009) Velandai Srikanth et al. NEUROBIOLOGY OF AGING
- Upregulation of BACE1 and β-Amyloid Protein Mediated by Chronic Cerebral Hypoperfusion Contributes to Cognitive Impairment and Pathogenesis of Alzheimer’s Disease
- (2009) Cai Zhiyou et al. NEUROCHEMICAL RESEARCH
- Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons
- (2009) L. B. Hoffman et al. NEUROLOGY
- Arterial Blood Gases and Oxygen Content in Climbers on Mount Everest
- (2009) Michael P.W. Grocott et al. NEW ENGLAND JOURNAL OF MEDICINE
- Selective Losses of Brainstem Catecholamine Neurons After Hypoxia-Ischemia in the Immature Rat Pup
- (2009) Kathryn M Buller et al. PEDIATRIC RESEARCH
- Caloric restriction improves memory in elderly humans
- (2009) A. V. Witte et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
- (2009) J.-E. Kang et al. SCIENCE
- Markers of glycemic control and insulin resistance in non-diabetic patients with Obstructive Sleep Apnea Hypopnea Syndrome: Does adherence to CPAP treatment improve glycemic control?
- (2009) Paschalis Steiropoulos et al. SLEEP MEDICINE
- Cerebral vasoreactivity decreases overnight in severe obstructive sleep apnea syndrome: A study of cerebral hemodynamics
- (2009) Martin Furtner et al. SLEEP MEDICINE
- Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8
- (2009) Giovanna E. Carpagnano et al. Translational Research
- Inflammation, Oxidative Stress, and the Vascular Endothelium in Obstructive Sleep Apnea
- (2009) Sanja Jelic et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Sleep-Disordered Breathing and Mortality: A Prospective Cohort Study
- (2009) Naresh M. Punjabi et al. PLOS MEDICINE
- (Pre)diabetes, brain aging, and cognition
- (2008) Jarbas S. Roriz-Filho et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Hypertension and Cerebrovascular Dysfunction
- (2008) Costantino Iadecola et al. Cell Metabolism
- Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications
- (2008) Karen Neumann et al. Current Alzheimer Research
- Neurobiology of Sleep Disturbances in Neurodegenerative Disorders
- (2008) J.-F. Gagnon et al. CURRENT PHARMACEUTICAL DESIGN
- Upper airway collapse and reopening induce inflammation in a sleep apnoea model
- (2008) I. Almendros et al. EUROPEAN RESPIRATORY JOURNAL
- Recurrent apnea induces neuronal apoptosis in the guinea pig forebrain
- (2008) Jian-Hua Zhang et al. EXPERIMENTAL NEUROLOGY
- Obstructive sleep apnea: the new cardiovascular disease. Part I: obstructive sleep apnea and the pathogenesis of vascular disease
- (2008) Rami Khayat et al. HEART FAILURE REVIEWS
- Blood Pressure Associated With Sleep-Disordered Breathing in a Population Sample of Children
- (2008) Edward O. Bixler et al. HYPERTENSION
- Anatomic distribution of apoptosis in medulla oblongata of infants and adults
- (2008) A. Porzionato et al. JOURNAL OF ANATOMY
- Impaired cerebral autoregulation in obstructive sleep apnea
- (2008) Fred Urbano et al. JOURNAL OF APPLIED PHYSIOLOGY
- Electron microscopy study of peripheral nerves in the uvulae of snorers and obstructive sleep apnoea patients
- (2008) A Bassiouny et al. JOURNAL OF LARYNGOLOGY AND OTOLOGY
- The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α
- (2008) Michela Guglielmotto et al. JOURNAL OF NEUROCHEMISTRY
- Calcium-dependent production of reactive oxygen species is involved in neuronal damage induced during glycolysis inhibition in cultured hippocampal neurons
- (2008) Karla Hernández-Fonseca et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Cognitive Effects of Treating Obstructive Sleep Apnea in Alzheimer's Disease: A Randomized Controlled Study
- (2008) Sonia Ancoli-Israel et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Reduced mammillary body volume in patients with obstructive sleep apnea
- (2008) Rajesh Kumar et al. NEUROSCIENCE LETTERS
- Obstructive Sleep Apnoea correlates with C-reactive protein in obese Asian Indians
- (2008) Bharat Bhushan et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Relationship between the severity of obstructive sleep apnea and impaired glucose metabolism in patients with obstructive sleep apnea
- (2008) Akira Tamura et al. RESPIRATORY MEDICINE
- Obstructive sleep apnea presenting as recurrent cardiopulmonary arrest
- (2008) See Meng Khoo et al. Sleep and Breathing
- New neurons in the adult brain: The role of sleep and consequences of sleep loss
- (2008) Peter Meerlo et al. SLEEP MEDICINE REVIEWS
- Pulse Pressure and Pulse Wave Velocity Are Related to Cognitive Decline in the Baltimore Longitudinal Study of Aging
- (2007) Shari R. Waldstein et al. HYPERTENSION
- Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP
- (2007) Liang Li et al. NEUROBIOLOGY OF AGING
- Differential age effects on cerebral blood flow and BOLD response to encoding: Associations with cognition and stroke risk
- (2007) Katherine J. Bangen et al. NEUROBIOLOGY OF AGING
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