Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

(2016) David J. Bonda et al.   Aging-US

Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-β and prion peptides

(2011) João P. Lopes et al.   CELL CYCLE

The familial Parkinson Disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E

(2011) Selvaraju Veeriah et al.   CELL CYCLE

Cdk5: Multitasking between physiological and pathological conditions

(2011) Joao P. Lopes et al.   PROGRESS IN NEUROBIOLOGY

The RB-E2F1 Pathway Regulates Autophagy

(2010) H. Jiang et al.   CANCER RESEARCH

Cdk5: Links to DNA damage

(2010) En Huang et al.   CELL CYCLE

Activation of ataxia telangiectasia muted under experimental models and human Parkinson’s disease

(2010) Antoni Camins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

JNK activation is regulated by E2F and promotes E2F1-induced apoptosis

(2010) Dana Bashari et al.   CELLULAR SIGNALLING

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death

(2010) En Huang et al.   NATURE CELL BIOLOGY

Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease

(2010) Maria Rosario Fernandez-Fernandez et al.   NEUROBIOLOGY OF DISEASE

6-Hydroxydopamine-Induced PC12 Cell Death is Mediated by MEF2D Down-regulation

(2010) Min-Kyoung Kim et al.   NEUROCHEMICAL RESEARCH

Cyclin D1 immunoreactivity changes in CA1 pyramidal neurons and dentate granule cells in the gerbil hippocampus after transient forebrain ischemia

(2010) Choong Hyun Lee et al.   NEUROLOGICAL RESEARCH

Review: Cell cycle aberrations and neurodegeneration

(2010) D. J. Bonda et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Genetic determinants at the interface of cancer and neurodegenerative disease

(2010) L G T Morris et al.   ONCOGENE

Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells

(2010) Javier G. Pizarro et al.   PHARMACOLOGICAL RESEARCH

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

(2009) Joao P. Lopes et al.   AGING CELL

Acetylation status of E2F-1 has an important role in the regulation of E2F-1-mediated transactivation of tumor suppressor p73

(2009) Toshinori Ozaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondria in Huntington's disease

(2009) Maria Damiano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A putative role for cell cycle-related proteins in microtubule-based neuroplasticity

(2009) Stefanie Schmetsdorf et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Regulation of E2F1-induced Apoptosis by the Nucleolar Protein RRP1B

(2009) Jason C. Paik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct and Indirect Roles of Cyclin-dependent Kinase 5 as an Upstream Regulator in the c-Jun NH2-Terminal Kinase Cascade: Relevance to Neurotoxic Insults in Alzheimer's Disease

(2009) Kai-Hui Sun et al.   MOLECULAR BIOLOGY OF THE CELL

The Cell Cycle Molecules Behind Neurodegeneration in Alzheimers Disease: Perspectives for Drug Development

(2008) A. Copani et al.   CURRENT MEDICINAL CHEMISTRY

The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle

(2008) Sharon Biton et al.   DNA REPAIR

Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid

(2008) Carme Pelegrí et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Differential Involvement of Cell Cycle Reactivation between Striatal and Cortical Neurons in Cell Death Induced by 3-Nitropropionic Acid

(2008) Hiroki Akashiba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction

(2008) Kai-Hui Sun et al.   JOURNAL OF NEUROCHEMISTRY

Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina

(2008) Deborah M. Wallace et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

(2008) Hyoung-gon Lee et al.   NEUROCHEMISTRY INTERNATIONAL

Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity

(2008) Dohoon Kim et al.   NEURON

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE

E2F – at the crossroads of life and death

(2008) Shirley Polager et al.   TRENDS IN CELL BIOLOGY

Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease

(2007) Daniel Alvira et al.   PARKINSONISM & RELATED DISORDERS