标题
DNA Modifications and Neurological Disorders
作者
关键词
DNA methylation, DNA demethylation, DNMT, TET, 5hmC, GADD45
出版物
Neurotherapeutics
Volume 10, Issue 4, Pages 556-567
出版商
Springer Nature
发表日期
2013-09-25
DOI
10.1007/s13311-013-0223-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma
- (2015) Nicola Amodio et al. Oncotarget
- The Role of 5-Hydroxymethylcytosine in Aging and Alzheimer’s Disease: Current Status and Prospects for Future Studies
- (2014) Daniel L.A. van den Hove et al. Current Alzheimer Research
- Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition
- (2013) Run-Rui Zhang et al. Cell Stem Cell
- MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer
- (2013) Junbo Zuo et al. MOLECULES AND CELLS
- Global Epigenomic Reconfiguration During Mammalian Brain Development
- (2013) R. Lister et al. SCIENCE
- Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis
- (2013) Maria A. Hahn et al. Cell Reports
- Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome
- (2012) Wei Xie et al. CELL
- MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System
- (2012) Marian Mellén et al. CELL
- Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development
- (2012) Yufei Xu et al. CELL
- Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy
- (2012) Juliane Winkelmann et al. HUMAN MOLECULAR GENETICS
- The role of activation-induced deaminase in antibody diversification and genomic instability
- (2012) Jing H. Wang IMMUNOLOGIC RESEARCH
- Differential DNA Methylation Patterns Define Status Epilepticus and Epileptic Tolerance
- (2012) S. F. C. Miller-Delaney et al. JOURNAL OF NEUROSCIENCE
- Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
- (2012) Peppi Koivunen et al. NATURE
- AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
- (2012) Christopher S Nabel et al. Nature Chemical Biology
- Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
- (2012) Torsten Klengel et al. NATURE NEUROSCIENCE
- Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities
- (2012) Ana M M Oliveira et al. NATURE NEUROSCIENCE
- The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders
- (2012) Dennis R Grayson et al. NEUROPSYCHOPHARMACOLOGY
- Distinct DNA methylomes of newborns and centenarians
- (2012) H. Heyn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients
- (2012) E Dong et al. Translational Psychiatry
- Mutations in ZBTB24 Are Associated with Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome Type 2
- (2011) Jessica C. de Greef et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective
- (2011) Michael R. Santoro et al. Annual Review of Pathology-Mechanisms of Disease
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
- (2011) Junjie U. Guo et al. CELL
- Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells
- (2011) Ozlem Yildirim et al. CELL
- α-Synuclein Sequesters Dnmt1 from the Nucleus
- (2011) Paula Desplats et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine
- (2011) Atanu Maiti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation
- (2011) B. A. Chestnut et al. JOURNAL OF NEUROSCIENCE
- Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder
- (2011) Tania L. Roth et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
- (2011) Christopher J Klein et al. NATURE GENETICS
- Neuronal activity modifies the DNA methylation landscape in the adult brain
- (2011) Junjie U Guo et al. NATURE NEUROSCIENCE
- 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging
- (2011) Keith E Szulwach et al. NATURE NEUROSCIENCE
- Abnormal Glucocorticoid Receptor mRNA and Protein Isoform Expression in the Prefrontal Cortex in Psychiatric Illness
- (2011) Duncan Sinclair et al. NEUROPSYCHOPHARMACOLOGY
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
- (2011) Y.-F. He et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
- (2010) Sha Zhao et al. ARTHRITIS AND RHEUMATISM
- Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1
- (2010) Jinfeng Huang et al. HEPATOLOGY
- Replication timing-related and gene body-specific methylation of active human genes
- (2010) Dvir Aran et al. HUMAN MOLECULAR GENETICS
- Possible involvement of DNA methylation in NKCC1 gene expression during postnatal development and in response to ischemia
- (2010) Hae-Ahm Lee et al. JOURNAL OF NEUROCHEMISTRY
- Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains
- (2010) A. Jowaed et al. JOURNAL OF NEUROSCIENCE
- Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
- (2010) Christian Popp et al. NATURE
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Conserved role of intragenic DNA methylation in regulating alternative promoters
- (2010) Alika K. Maunakea et al. NATURE
- Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
- (2010) Chun-Xiao Song et al. NATURE BIOTECHNOLOGY
- Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
- (2010) Jian Feng et al. NATURE NEUROSCIENCE
- Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway
- (2010) P. Hajkova et al. SCIENCE
- Active DNA Demethylation Mediated by DNA Glycosylases
- (2009) Jian-Kang Zhu Annual Review of Genetics
- Regulation of Oestrogen Receptor Gene Expression: New Insights and Novel Mechanisms
- (2009) M. E. Wilson et al. JOURNAL OF NEUROENDOCRINOLOGY
- Increased Reelin Promoter Methylation Is Associated With Granule Cell Dispersion in Human Temporal Lobe Epilepsy
- (2009) Katja Kobow et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
- (2009) Madeleine P Ball et al. NATURE BIOTECHNOLOGY
- Dynamic DNA methylation programs persistent adverse effects of early-life stress
- (2009) Chris Murgatroyd et al. NATURE NEUROSCIENCE
- The Methyl-CpG Binding Proteins Mecp2, Mbd2 and Kaiso Are Dispensable for Mouse Embryogenesis, but Play a Redundant Function in Neural Differentiation
- (2009) Isabel Martín Caballero et al. PLoS One
- An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes
- (2009) A. Zhubi et al. SCHIZOPHRENIA RESEARCH
- Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis
- (2009) D. K. Ma et al. SCIENCE
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
- Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context
- (2009) Brock C. Christensen et al. PLoS Genetics
- Epigenomic Profiling Reveals DNA-Methylation Changes Associated with Major Psychosis
- (2008) Jonathan Mill et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The epigenetic effects of amyloid-β1–40 on global DNA and neprilysin genes in murine cerebral endothelial cells
- (2008) Kun-Lin Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45
- (2008) Kunal Rai et al. CELL
- Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?
- (2008) T. Clouaire et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory
- (2008) F. D. Lubin et al. JOURNAL OF NEUROSCIENCE
- Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation
- (2008) E. D. Nelson et al. JOURNAL OF NEUROSCIENCE
- Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
- (2008) E. Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-148 targets human DNMT3b protein coding region
- (2008) A. M. Duursma et al. RNA
- MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription
- (2008) M. Chahrour et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started