Article
Neurosciences
Jingsong Ma, Mingzhe Zhao, Wei Zhou, Mo Li, Cong Huai, Lu Shen, Ting Wang, Hao Wu, Na Zhang, Zhiruo Zhang, Lin He, Shengying Qin
Summary: The study used meta-analysis to demonstrate a significant association between COMT Val158Met polymorphism and antipsychotic response, which was consistent in both Caucasian and Asian patient populations. Genotyping of patients for predicting antipsychotic response may be relevant for future randomized clinical trials.
CURRENT NEUROPHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Sadiatul Marzan, Md. Abdul Aziz, Mohammad Safiqul Islam
Summary: This meta-analysis found that the rs7341475 polymorphism of the RELN gene is associated with a lower risk of SCZ in the overall population and Caucasian population, while rs262355 is associated with an increased risk of SCZ only in the Caucasian population.
JOURNAL OF MOLECULAR NEUROSCIENCE
(2021)
Article
Veterinary Sciences
In-Soon Roh, Yong-Chan Kim, Sae-Young Won, Kyung-Je Park, Hoo-Chang Park, Ji-Yong Hwang, Hae-Eun Kang, Hyun-Joo Sohn, Byung-Hoon Jeong
Summary: This study aimed to evaluate the association between the M132L single nucleotide polymorphism (SNP) and susceptibility to chronic wasting disease (CWD) in Korean elk. However, our results showed no significant association between the M132L SNP and susceptibility to CWD in Korean elk.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Xinyao Meng, Ji-Long Zheng, Mao-Ling Sun, Hai-Yun Lai, Bao-Jie Wang, Jun Yao, Hongbo Wang
Summary: This meta-analysis investigated the relationship between MTHFR gene polymorphisms and psychiatric disorders. The findings suggested that certain MTHFR polymorphisms were associated with the occurrence of specific disorders.
Article
Public, Environmental & Occupational Health
Liwei Cheng, Fan Zhang, Ying Wang, Jing Chen, Xiaoping Yuan
Summary: This meta-analysis study found an association between IFNGR1 gene polymorphisms and tuberculosis susceptibility. The rs2234711 polymorphism was associated with increased tuberculosis susceptibility in Africans and decreased susceptibility in Asians. Additionally, the rs7749390 polymorphism was associated with decreased tuberculosis susceptibility in Africans.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Genetics & Heredity
Xu Han, Lai Zheng, Yi-Yang Mu, Hong-Zhuo Li, Xiao-Feng He
Summary: The meta-analysis investigated the association between OPG gene polymorphisms and osteoporosis risk, finding a significant correlation in certain subgroups but overall pointing to false-positive results. This suggests that previous studies may not have accurately assessed the true association between OPG gene variants and osteoporosis risk.
FRONTIERS IN GENETICS
(2022)
Article
Medical Laboratory Technology
Xing Ren, Aiyou Mao, Shumin Tan, Jiaxiu Liu, Xiaobin Wei
Summary: This study found that MICA*002:01, MICA*A4, and MICA*A9 may be susceptibility alleles for schizophrenia in the Han population, while MICA gene polymorphism is not associated with schizophrenia in the Li population.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Article
Psychiatry
Hae Jeong Park, Won Sub Kang, Jong Woo Kim
Summary: Previous studies have suggested that the TGA haplotype of RTN4 is significantly associated with schizophrenia, potentially increasing the susceptibility to the disorder. The rare TGA haplotype was shown to decrease promoter activity, further supporting its role in the pathogenesis of schizophrenia.
PSYCHIATRY RESEARCH
(2021)
Review
Psychiatry
Sidi He, Lei Zhang, Shunying Yu, Wenjuan Yu, Yimin Yu, Jingjing Huang, Huafang Li
Summary: For the TNF-α -1031T/C polymorphism, there is controversy over its association with schizophrenia risk, but consistent results show that the T allele decreases schizophrenia risk in the allele model and the TC + CC genotype increases schizophrenia risk in the dominant model. In the East Asian population, the T allele is associated with a reduced risk of schizophrenia.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE
(2022)
Review
Medicine, General & Internal
Guang-Xing Tan, Lin Jiang, Gang-Qin Li, Kuan Bai
Summary: This study found an association between MTHFR gene polymorphism and azoospermia, with significant links observed between C677T and A1298C polymorphisms and azoospermia. Caucasian populations had a higher risk than Mongolian populations in the association between MTHFR and azoospermia.
Article
Neurosciences
Pan Yan, Bing Gao, Shuqi Wang, Shengdong Wang, Jing Li, Mingfen Song
Summary: The meta-analysis revealed a significant association between the 5-HTR2A gene's A-1438G polymorphism and the clinical response of schizophrenia patients to atypical antipsychotic treatment, particularly prominent in Asians and patients treated with olanzapine.
NEUROSCIENCE LETTERS
(2022)
Review
Genetics & Heredity
Lin Zhao, Xiang-Xiongyi Yin, Jun Qin, Wei Wang, Xiao-Feng He
Summary: Based on a comprehensive analysis of a large number of studies, this meta-analysis found no significant association between TP53 codons 72, IVS3 16 bp, and IVS6+62A > G polymorphisms and breast cancer risk. The previous results suggesting an association may be false-positive results due to confounding factors.
FRONTIERS IN GENETICS
(2022)
Review
Obstetrics & Gynecology
Yuxi Li, Lanlan Fang, Yang Yan, Zhen Wang, Ze Wu, Qiongqiong Jia, Jung-Chien Cheng, Ying-Pu Sun
Summary: The presence of a polymorphism of eight or more SHBG (TAAAA)n may be a predictive factor for the risk of PCOS, as it is associated with PCOS risk and low serum SHBG concentrations in women with PCOS. Other SHBG gene polymorphisms were not significantly associated with either PCOS risk or serum SHBG concentrations.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Medicine, General & Internal
Won Sub Kang, Sang Min Lee, Dongkee Hwang, Hae Jeong Park, Jong Woo Kim
Summary: Accumulating evidence suggests that the autophagy process is involved in the pathogenesis of schizophrenia. This study found that specific ULK2 polymorphisms are associated with susceptibility to schizophrenia in the Korean population.
Review
Psychiatry
Valentina Baldini, Ramona Di Stefano, Lorenzo Vittorio Rindi, Anthony Ahmed, Maju Mathew Koola, Marco Solmi, Davide Papola, Diana De Ronchi, Corrado Barbui, Giovanni Ostuzzi
Summary: This study aims to assess the association between adverse childhood experiences and suicidal behaviors in individuals with schizophrenia spectrum disorders. Meta-analysis of 21 eligible studies revealed a strong positive association between adverse childhood experiences and suicide behaviors in people with schizophrenia spectrum disorders.
PSYCHIATRY RESEARCH
(2023)
Article
Ophthalmology
Yong-Kyu Kim, Su Young Moon, Kyung Mi Yim, Su Jeong Seong, Jae Yeon Hwang, Sung Pyo Park
JOURNAL OF OPHTHALMOLOGY
(2017)
Article
Mathematical & Computational Biology
Kyungchul Noh, Kyung Soon Shin, Dongkwan Shin, Jae Yeon Hwang, June Sic Kim, Joon Hwan Jang, Chun Kee Chung, Jun Soo Kwon, Kwang-Hyun Cho
BMC SYSTEMS BIOLOGY
(2013)
Article
Pharmacology & Pharmacy
Jun Soo Kwon, Aurelia Mittoux, Jae Yeon Hwang, Adeline Ong, Zhuo-Ji Cai, Tung-Ping Su
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
(2012)
Article
Engineering, Electrical & Electronic
Joon Hwan Jang, Je-Yeon Yun, Wi Hoon Jung, Geumsook Shim, Min Soo Byun, Jae Yeon Hwang, Sung Nyun Kim, Chi-Hoon Choi, Jun Soo Kwon
INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY
(2012)
Article
Psychology, Biological
Jung-Seok Choi, Su Mi Park, Jaewon Lee, Jae Yeon Hwang, Hee Yeon Jung, Sam-Wook Choi, Dai Jin Kim, Sohee Oh, Jun-Young Lee
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2013)
Article
Psychology
Na Young Shin, Joon Hwan Jang, Hee Sun Kim, Geumsook Shim, Jae Yeon Hwang, Sung Nyun Kim, Jun Soo Kwon
JOURNAL OF NEUROPSYCHOLOGY
(2013)
Article
Clinical Neurology
Na Young Shin, Do-Hyung Kang, Joon Hwan Jang, Soo Young Park, Jae Yeon Hwang, Sung Nyun Kim, Min Soo Byun, Hye Youn Park, Yong Chul Kim
Article
Multidisciplinary Sciences
Jung-Seok Choi, Young-Chul Shin, Wi Hoon Jung, Joon Hwan Jang, Do-Hyung Kang, Chi-Hoon Choi, Sam-Wook Choi, Jun-Young Lee, Jae Yeon Hwang, Jun Soo Kwon
Article
Clinical Neurology
Jaewon Lee, Jae Yeon Hwang, Su Mi Park, Hee Yeon Jung, Sam-Wook Choi, Dai Jin Kim, Jun-Young Lee, Jung-Seok Choi
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2014)
Article
Psychiatry
Do-Hyeong Lee, Eun Chung Noh, Yong Chul Kim, Jae Yeon Hwang, Sung Nyun Kim, Joon Hwan Jang, Min Soo Byun, Do-Hyung Kang
PSYCHIATRY INVESTIGATION
(2014)
Article
Psychiatry
Jung-Seok Choi, Su Mi Park, Myoung-Sun Roh, Jun-Young Lee, Chan-Bin Park, Jae Yeon Hwang, Ah Reum Gwak, Hee Yeon Jung
PSYCHIATRY RESEARCH
(2014)
Article
Psychiatry
Hye Youn Park, Jae Yeon Hwang, Wi Hoon Jung, Na Young Shin, Geumsook Shim, Joon Hwan Jang, Jun Soo Kwon
SCHIZOPHRENIA RESEARCH
(2013)
Article
Psychiatry
Jae Yeon Hwang, Jung-Seok Choi, Ah Reum Gwak, Dawn Jung, Sam-Wook Choi, Jaewon Lee, Jun-Young Lee, Hee Yeon Jung, Dai Jin Kim
ANNALS OF GENERAL PSYCHIATRY
(2014)
Article
Health Care Sciences & Services
Kiwon Kim, Hong Jin Jeon, Woojae Myung, Seung Wan Suh, Su Jeong Seong, Jae Yeon Hwang, Je Il Ryu, Seon-Cheol Park
Summary: Late-onset psychosis requires careful intervention due to the greater associated risks, higher morbidity and mortality rates, and complicated treatment considerations, which may be attributed to the higher incidence of adverse effects despite the black box warning against antipsychotics.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Psychology, Social
Chan-Bin Park, Jung-Seok Choi, Su Mi Park, Jun-Young Lee, Hee Yeon Jung, Jin-Mi Seol, Jae Yeon Hwang, Ah Reum Gwak, Jun Soo Kwon
CYBERPSYCHOLOGY BEHAVIOR AND SOCIAL NETWORKING
(2014)