mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning

Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm

(2008) Justin M. Darrah et al.   BEHAVIOURAL PHARMACOLOGY

Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro

(2008) Sergey Neyman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

ADX47273 [S-(4-Fluoro-phenyl)- -methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities

(2008) F. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY

MGluR5 Mediates the Interaction between Late-LTP, Network Activity, and Learning

(2008) Arthur Bikbaev et al.   PLoS One

Local facilitation of hippocampal metabotropic glutamate receptor-dependent long-term depression by corticosterone and dexamethasone

(2008) Francis Chaouloff et al.   PSYCHONEUROENDOCRINOLOGY

Attenuation of ketamine-evoked behavioral responses by mGluR5 positive modulators in mice

(2008) Ming-Huan Chan et al.   PSYCHOPHARMACOLOGY

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

(2008) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES