The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

Cooperation Between Integrins and Growth Factor Receptors in Signaling and Endocytosis

(2011) Johanna Ivaska et al.   Annual Review of Cell and Developmental Biology

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression

(2011) Marta A. Dozynkiewicz et al.   DEVELOPMENTAL CELL

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

The Arp2/3 activator WASH regulates  5 1-integrin-mediated invasive migration

(2011) T. Zech et al.   JOURNAL OF CELL SCIENCE

Regulation of integrins by conformation and traffic: it takes two to tango

(2011) Donatella Valdembri et al.   Molecular BioSystems

SHARPIN is an endogenous inhibitor of β1-integrin activation

(2011) Juha K. Rantala et al.   NATURE CELL BIOLOGY

Phosphoinositide Regulation of Integrin Trafficking Required for Muscle Attachment and Maintenance

(2011) Inês Ribeiro et al.   PLoS Genetics

R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis

(2010) Matthew W Conklin et al.   BMC CELL BIOLOGY

Endothelial  5 and  v integrins cooperate in remodeling of the vasculature during development

(2010) A. van der Flier et al.   DEVELOPMENT

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Focal adhesions are sites of integrin extension

(2010) Janet A. Askari et al.   JOURNAL OF CELL BIOLOGY

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

The endocytic matrix

(2010) Giorgio Scita et al.   NATURE

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fibronectins in vascular morphogenesis

(2009) Sophie Astrof et al.   ANGIOGENESIS

Actin Dynamics at the Leading Edge: From Simple Machinery to Complex Networks

(2009) Robert H. Insall et al.   DEVELOPMENTAL CELL

Regulation of Angiogenesis by Oxygen and Metabolism

(2009) Peter Fraisl et al.   DEVELOPMENTAL CELL

Different Requirement for Rnd GTPases of R-Ras GAP Activity of Plexin-C1 and Plexin-D1

(2009) Kanami Uesugi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrins in cell migration - the actin connection

(2009) M. Vicente-Manzanares et al.   JOURNAL OF CELL SCIENCE

New susceptibility locus for coronary artery disease on chromosome 3q22.3

(2009) Jeanette Erdmann et al.   NATURE GENETICS

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module

(2009) Matteo Bolomini-Vittori et al.   NATURE IMMUNOLOGY

Integrins: masters and slaves of endocytic transport

(2009) Patrick T. Caswell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Endocytic Trafficking of Rac Is Required for the Spatial Restriction of Signaling in Cell Migration

(2008) Andrea Palamidessi et al.   CELL

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects

(2008) Ying Zhang et al.   DEVELOPMENTAL BIOLOGY

An essential role for Rac1 in endothelial cell function and vascular development

(2008) Wenfu Tan et al.   FASEB JOURNAL

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endosomal Phosphoinositides and Human Diseases

(2008) Anne-Sophie Nicot et al.   TRAFFIC

Endosomal trafficking of Src tyrosine kinase

(2008) Emma Sandilands et al.   TRENDS IN CELL BIOLOGY