The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma

Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study

(2011) Maryam Fouladi et al.   JOURNAL OF CLINICAL ONCOLOGY

Underexpressed microRNA-199b-5p targets Hypoxia-Inducible Factor-1α in hepatocellular carcinoma and predicts prognosis of hepatocellular carcinoma patients

(2011) Chuanxi Wang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Notch signalling is off and is uncoupled from HES1 expression in Ewing's sarcoma

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ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration

(2010) Liangping Yuan et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Notch Target Hes1 Directly Modulates Gli1 Expression and Hedgehog Signaling: A Potential Mechanism of Therapeutic Resistance

(2010) K. C. Schreck et al.   CLINICAL CANCER RESEARCH

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

(2010) Emma L Clayton et al.   NATURE NEUROSCIENCE

The many roles of microRNAs in brain tumor biology

(2010) Jay D. Turner et al.   Neurosurgical Focus

Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma

(2010) E Julian et al.   ONCOGENE

Notch signaling is not essential in sonic hedgehog-activated medulloblastoma

(2010) B A Hatton et al.   ONCOGENE

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma

(2009) Tracy-Ann Read et al.   CANCER CELL

Multipotent CD15+ Cancer Stem Cells in Patched-1-Deficient Mouse Medulloblastoma

(2009) R. J. Ward et al.   CANCER RESEARCH

The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog-Treated Cerebellar Neural Precursors

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Hedgehog signalling: Emerging evidence for non-canonical pathways

(2009) Dagan Jenkins   CELLULAR SIGNALLING

MicroRNAs and cancer epigenetics: a macrorevolution

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A study of microRNAsin silicoandin vivo: diagnostic and therapeutic applications in cancer

(2009) Scott A. Waldman et al.   FEBS Journal

Outcome Prediction in Pediatric Medulloblastoma Based on DNA Copy-Number Aberrations of Chromosomes 6q and 17q and theMYCandMYCNLoci

(2009) Stefan Pfister et al.   JOURNAL OF CLINICAL ONCOLOGY

Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor

(2009) T. J. Abouantoun et al.   MOLECULAR CANCER THERAPEUTICS

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

(2009) Paul A Northcott et al.   NATURE GENETICS

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

(2009) Livia Garzia et al.   PLoS One

Amplification and Overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in Medulloblastoma

(2009) Yuan Lu et al.   PLoS One

ThemiR-17∼92cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

(2009) Tamar Uziel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origins of Medulloblastoma Subtypes

(2008) Richard J. Gilbertson et al.   Annual Review of Pathology-Mechanisms of Disease

Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

(2008) M. Toyota et al.   CANCER RESEARCH

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

(2008) Elisabetta Ferretti et al.   EMBO JOURNAL

MicroRNA profiling in human medulloblastoma

(2008) Elisabetta Ferretti et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma

(2008) Jessica Pierson et al.   JOURNAL OF NEURO-ONCOLOGY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE