Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism
出版年份 2012 全文链接
标题
Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism
作者
关键词
-
出版物
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Volume 385, Issue 4, Pages 337-372
出版商
Springer Nature
发表日期
2012-02-13
DOI
10.1007/s00210-012-0734-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular properties affecting fast dissociation from the D2 receptor
- (2011) Gary Tresadern et al. BIOORGANIC & MEDICINAL CHEMISTRY
- P02-314 - Membrane lipid rafts are required for D2 dopamine receptor signaling
- (2011) D. Sibley et al. EUROPEAN PSYCHIATRY
- Association of Candesartan vs Losartan With All-Cause Mortality in Patients With Heart Failure
- (2011) Maria Eklind-Cervenka JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Binding of “AT4 receptor” ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells
- (2011) Heidi Demaegdt et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Anatomically distinct dopamine release during anticipation and experience of peak emotion to music
- (2011) Valorie N Salimpoor et al. NATURE NEUROSCIENCE
- Understanding wiring and volume transmission
- (2010) Luigi F. Agnati et al. BRAIN RESEARCH REVIEWS
- Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays
- (2010) Steven J Charlton et al. BRITISH JOURNAL OF PHARMACOLOGY
- Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a ‘two-step’ competition binding approach
- (2010) A Packeu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action
- (2010) Georges Vauquelin et al. BRITISH JOURNAL OF PHARMACOLOGY
- Presynaptic Dopamine in Schizophrenia
- (2010) Nobumi Miyake et al. CNS Neuroscience & Therapeutics
- All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High Receptors
- (2010) Philip Seeman CNS Neuroscience & Therapeutics
- P.3.c.046 Efficacy and safety of JNJ 37822681, a fast dissociating D2 receptor antagonist, in the treatment of schizophrenia
- (2010) M. Schmidt et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- P.3.d.009 Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia
- (2010) X. Langlois et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Rebinding: or why drugs may act longerin vivothan expected from theirin vitrotarget residence time
- (2010) Georges Vauquelin Expert Opinion on Drug Discovery
- The dynamics of drug-target interactions: drug-target residence time and its impact on efficacy and safety
- (2010) Robert A Copeland Expert Opinion on Drug Discovery
- Binding kinetics and mechanism of action: toward the discovery and development of better and best in class drugs
- (2010) Rumin Zhang et al. Expert Opinion on Drug Discovery
- Antagonist-D2S-dopamine receptors interactions in intact Chinese recombinant ovary cells
- (2010) Ann Packeu et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Synthesis and Evaluation of a Set of 4-Phenylpiperidines and 4-Phenylpiperazines as D2Receptor Ligands and the Discovery of the Dopaminergic Stabilizer 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine (Huntexil, Pridopidine, ACR16)
- (2010) Fredrik Pettersson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Influence of Phasic and Tonic Dopamine Release on Receptor Activation
- (2010) J. K. Dreyer et al. JOURNAL OF NEUROSCIENCE
- Detection of angiotensin II type 1 receptor ligands by a cell-based assay
- (2009) Matthias Grießner et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Molecular mechanisms for the persistent bronchodilatory effect of the β2-adrenoceptor agonist salmeterol
- (2009) A Szczuka et al. BRITISH JOURNAL OF PHARMACOLOGY
- Incorporating Receptor Theory in Mechanism-Based Pharmacokinetic-Pharmacodynamic (PK-PD) Modeling
- (2009) Bart A. Ploeger et al. Drug Metabolism and Pharmacokinetics
- Receptor reserve-dependent properties of antipsychotics at human dopamine D2 receptors
- (2009) Yoshihiro Tadori et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The dopaminergic stabilizers pridopidine (ACR16) and (−)-OSU6162 display dopamine D2 receptor antagonism and fast receptor dissociation properties
- (2009) Tino Dyhring et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Non-competitive interaction between raclopride and spiperone on human D2L-receptors in intact Chinese hamster ovary cells
- (2009) Ann Packeu et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Paracrine Transactivation of the CB1Cannabinoid Receptor by AT1Angiotensin and Other Gq/11Protein-coupled Receptors
- (2009) Gábor Turu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension
- (2009) S E Kjeldsen et al. JOURNAL OF HUMAN HYPERTENSION
- Schizophrenia
- (2009) Jim van Os et al. LANCET
- Ligands, their receptors and … plasma membranes
- (2009) G. Vauquelin et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Impact of D2 Receptor Internalization on Binding Affinity of Neuroimaging Radiotracers
- (2009) Ningning Guo et al. NEUROPSYCHOPHARMACOLOGY
- Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2and D3dopamine receptors
- (2009) Mette Skinbjerg et al. SYNAPSE
- Antagonist-radioligand binding to D2L-receptors in intact cells
- (2008) Ann Packeu et al. BIOCHEMICAL PHARMACOLOGY
- Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function
- (2008) Peter J. Tummino et al. BIOCHEMISTRY
- Dopamine spillover after quantal release: Rethinking dopamine transmission in the nigrostriatal pathway
- (2008) Margaret E. Rice et al. BRAIN RESEARCH REVIEWS
- Translocation of the insulin-regulated aminopeptidase to the cell surface: detection by radioligand binding
- (2008) H Demaegdt et al. BRITISH JOURNAL OF PHARMACOLOGY
- Using pharmacokinetic–pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics
- (2008) Christina Kurre Olsen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The role of D1–D2 receptor hetero-dimerization in the mechanism of action of clozapine
- (2008) Agata Faron-Górecka et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Restricted Collision Coupling of the A2AReceptor Revisited
- (2008) Christoforos Charalambous et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dose–Occupancy Study of Striatal and Extrastriatal Dopamine D2 Receptors by Aripiprazole in Schizophrenia with PET and [18F]Fallypride
- (2008) Lawrence S Kegeles et al. NEUROPSYCHOPHARMACOLOGY
- Antagonism of dopamine D2 receptor/ -arrestin 2 interaction is a common property of clinically effective antipsychotics
- (2008) B. Masri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dopamine D2Highreceptors measured ex vivo are elevated in amphetamine-sensitized animals
- (2008) Philip Seeman SYNAPSE
- G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes
- (2007) Adriano Marchese et al. Annual Review of Pharmacology and Toxicology
- Heterotrimeric G protein activation by G-protein-coupled receptors
- (2007) William M. Oldham et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started