Mast cells: an expanding pathophysiological role from allergy to other disorders

Amyloid β Peptides Trigger CD47-Dependent Mast Cell Secretory and Phagocytic Responses

(2017) N. Niederhoffer et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Mast Cells Contribute to Autoimmune Inflammatory Arthritis via Their Tryptase/Heparin Complexes

(2014) K. Shin et al.   JOURNAL OF IMMUNOLOGY

Ameliorative potential of sodium cromoglycate and diethyldithiocarbamic acid in restraint stress-induced behavioral alterations in rats

(2014) Rajneet K. Manchanda et al.   Pharmacological Reports

Intestinal Serotonin Release, Sensory Neuron Activation and Abdominal Pain in Irritable Bowel Syndrome

(2011) Cesare Cremon et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

(2011) David Montani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Relevance of mast cell–nerve interactions in intestinal nociception

(2011) Sophie A. van Diest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New insights into the role of mast cells in autoimmunity: Evidence for a common mechanism of action?

(2011) Margaret E. Walker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SCF and TLR4 ligand cooperate to augment the tumor-promoting potential of mast cells

(2011) Jing-Jing Wei et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Mast Cell Targeting Hampers Prostate Adenocarcinoma Development but Promotes the Occurrence of Highly Malignant Neuroendocrine Cancers

(2011) P. Pittoni et al.   CANCER RESEARCH

Mast Cell Inhibition Improves Pulmonary Vascular Remodeling in Pulmonary Hypertension

(2011) Beatrijs Bartelds et al.   CHEST

Mast Cells in Tumor Microenvironment Promotes the In Vivo Growth of Pancreatic Ductal Adenocarcinoma

(2011) D. Z. Chang et al.   CLINICAL CANCER RESEARCH

Mast cell stabilization: novel medication for obesity and diabetes

(2011) Jing Wang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Pathogenic role of mast cells in the development of diabetic nephropathy: a study of patients at different stages of the disease

(2011) J. M. Zheng et al.   DIABETOLOGIA

The role of mast cells in male infertility

(2011) Gerd Haidl et al.   Expert Review of Clinical Immunology

Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling

(2011) M. Adam et al.   HUMAN REPRODUCTION

Cutting Edge: Mast Cells Regulate Disease Severity in a Relapsing-Remitting Model of Multiple Sclerosis

(2011) B. A. Sayed et al.   JOURNAL OF IMMUNOLOGY

Kit (W-sh) Mice Develop Earlier and More Severe Experimental Autoimmune Encephalomyelitis Due to Absence of Immune Suppression

(2011) H. Li et al.   JOURNAL OF IMMUNOLOGY

Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient KitW-sh/W-sh mice

(2011) Silvia Piconese et al.   LABORATORY INVESTIGATION

Mast cells and histamine enhance the proliferation of non-small cell lung cancer cells

(2011) Evgeniy Stoyanov et al.   LUNG CANCER

Central Nervous System Mast Cells in Peripheral Inflammatory Nociception

(2011) Dimitris N Xanthos et al.   Molecular Pain

Palmitoylethanolamide Reduces Granuloma-Induced Hyperalgesia by Modulation of Mast Cell Activation in Rats

(2011) Daniele De Filippis et al.   Molecular Pain

Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature

(2011) Christoph A. Reichel et al.   PLoS One

Cerebral Mast Cells Mediate Blood-Brain Barrier Disruption in Acute Experimental Ischemic Stroke Through Perivascular Gelatinase Activation

(2011) Olli S. Mattila et al.   STROKE

Mast cells in atherosclerosis

(2011) Erik Biessen et al.   THROMBOSIS AND HAEMOSTASIS

Mast cells squeeze the heart and stretch the gird: Their role in atherosclerosis and obesity

(2011) Theoharis C. Theoharides et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Evidence for Mast Cell Activation in Patients with Therapy-Resistant Irritable Bowel Syndrome

(2011) T. Frieling et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

(2011) Jolien Suurmond et al.   ARTHRITIS RESEARCH & THERAPY

Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial

(2011) François Piette et al.   Alzheimers Research & Therapy

Potential Targeting of Siglecs, Mast Cell Inhibitory Receptors, in Interstitial Cystitis

(2011) Chang-Shin Park et al.   International Neurourology Journal

New Insights into the Mechanism of the Down-Regulation of Mast Cells in the Treatment of Interstitial Cystitis: Possible Role of Siglecs

(2011) Tack Lee   International Neurourology Journal

Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling

(2010) Norifumi Sawamukai et al.   ARTHRITIS AND RHEUMATISM

Mast cells and metabolic syndrome

(2010) Jie Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Higher levels of cell apoptosis and abnormal E-cadherin expression in the urothelium are associated with inflammation in patients with interstitial cystitis/painful bladder syndrome

(2010) Jia-Heng Shie et al.   BJU INTERNATIONAL

Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress

(2010) María Vicario et al.   BRAIN BEHAVIOR AND IMMUNITY

The anti-allergic compound tranilast attenuates inflammation and inhibits bone destruction in collagen-induced arthritis in mice

(2010) N Shiota et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE−/− mice

(2010) Ilze Bot et al.   CARDIOVASCULAR RESEARCH

ERK1/2 signaling pathway in mast cell activation-induced sensitization of esophageal nodose C-fiber neurons

(2010) G. Gao et al.   DISEASES OF THE ESOPHAGUS

Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity

(2010) Stephen J. Galli et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting of c-kit+ haematopoietic progenitor cells prevents hypoxic pulmonary hypertension

(2010) N. Gambaryan et al.   EUROPEAN RESPIRATORY JOURNAL

Imatinib inhibits bone marrow-derived c-kit+ cell mobilisation in hypoxic pulmonary hypertension

(2010) N. Gambaryan et al.   EUROPEAN RESPIRATORY JOURNAL

Mast cells promote lung vascular remodelling in pulmonary hypertension

(2010) J. Hoffmann et al.   EUROPEAN RESPIRATORY JOURNAL

The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome

(2010) T. K. Klooker et al.   GUT

YKL-40 and mast cells are associated with detrusor fibrosis in patients diagnosed with bladder pain syndrome/interstitial cystitis according to the 2008 criteria of the European Society for the Study of Interstitial Cystitis

(2010) Benedikte Richter et al.   HISTOPATHOLOGY

The role of mast cells and their mediators in reproduction, pregnancy and labour

(2010) F. M. Menzies et al.   HUMAN REPRODUCTION UPDATE

Zaditen (Ketotifen), as mast cell blocker, improves sperm quality, chromatin integrity and pregnancy rate after varicocelectomy

(2010) L. Azadi et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Mast Cells as Early Responders in the Regulation of Acute Blood–Brain Barrier Changes after Cerebral Ischemia and Hemorrhage

(2010) Perttu Johannes Lindsberg et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Signaling Pathways in the Activation of Mast Cells Cocultured with Astrocytes and Colocalization of Both Cells in Experimental Allergic Encephalomyelitis

(2010) D. Y. Kim et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

(2010) A. J. Hueber et al.   JOURNAL OF IMMUNOLOGY

Meningeal Mast Cells Affect Early T Cell Central Nervous System Infiltration and Blood-Brain Barrier Integrity through TNF: A Role for Neutrophil Recruitment?

(2010) B. A. Sayed et al.   JOURNAL OF IMMUNOLOGY

An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse

(2010) Tatiana Aparecida Pimentel et al.   LABORATORY INVESTIGATION

JNK1 controls mast cell degranulation and IL-1  production in inflammatory arthritis

(2010) M. Guma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of Mast Cell Degranulation by Disodium Cromoglycate Delayed the Regression of Hypoxic Pulmonary Hypertension in Rats

(2010) Hana Maxová et al.   RESPIRATION

TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus

(2009) Shaoyong Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mast cells in the seminal plasma of infertile men as detected by flow cytometry

(2009) J.-P. Allam et al.   ANDROLOGIA

An emerging role of mast cells in cerebral ischemia and hemorrhage

(2009) Daniel Strbian et al.   ANNALS OF MEDICINE

Human Mast Cells Stimulate Activated T Cells

(2009) Theoharis C. Theoharides et al.   Annals of the New York Academy of Sciences

Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis

(2009) Tao Guo et al.   ATHEROSCLEROSIS

Short Communication: The Neuropeptide Substance P Mediates Adventitial Mast Cell Activation and Induces Intraplaque Hemorrhage in Advanced Atherosclerosis

(2009) Ilze Bot et al.   CIRCULATION RESEARCH

Serotonin and pulmonary hypertension—from bench to bedside?

(2009) Margaret R MacLean et al.   CURRENT OPINION IN PHARMACOLOGY

Mast Cells as Target in Cancer Therapy

(2009) Tom Kormelink et al.   CURRENT PHARMACEUTICAL DESIGN

Unbalanced expression of protease-activated receptors-1 and -2 in the colon of diarrhea-predominant irritable bowel syndrome patients

(2009) Zhao Xiang Bian et al.   JOURNAL OF GASTROENTEROLOGY

Bone Marrow-Derived Mast Cells Accumulate in the Central Nervous System During Inflammation but Are Dispensable for Experimental Autoimmune Encephalomyelitis Pathogenesis

(2009) J. L. Bennett et al.   JOURNAL OF IMMUNOLOGY

Role of the innate immune system in the pathogenesis of multiple sclerosis

(2009) Roopali Gandhi et al.   JOURNAL OF NEUROIMMUNOLOGY

Luteolin as a therapeutic option for multiple sclerosis

(2009) Theoharis C Theoharides   Journal of Neuroinflammation

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

(2009) Paul M. Hassoun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

Models and Mechanisms of Hyperalgesia and Allodynia

(2009) Jürgen Sandkühler   PHYSIOLOGICAL REVIEWS

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis

(2008) H. Patrick McNeil et al.   ARTHRITIS AND RHEUMATISM

Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats

(2008) Hei Zi-qing et al.   BMC GASTROENTEROLOGY

A protective role of mast cells in intestinal tumorigenesis

(2008) Mark J. Sinnamon et al.   CARCINOGENESIS

Infiltration of Mast Cells in Rat Colon Is a Consequence of Ischemia/Reperfusion

(2008) Elin Sand et al.   DIGESTIVE DISEASES AND SCIENCES

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

(2008) Sofia E. Magnusson et al.   FASEB JOURNAL

Implication of mast cell degranulation in ischemic preconditioning-induced prevention of cerebral injury

(2008) Ashish K Rehni et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Mast-cell-dependent secretion of CXC chemokines regulates ischemia-reperfusion-induced leukocyte recruitment in the colon

(2008) Stefan Santen et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Mast cell transcripts are increased within and outside multiple sclerosis lesions

(2008) Nicolas Couturier et al.   JOURNAL OF NEUROIMMUNOLOGY

Mast Cell-Derived Histamine Mediates Cystitis Pain

(2008) Charles N. Rudick et al.   PLoS One

Brain mast cells link the immune system to anxiety-like behavior

(2008) K. M. Nautiyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of Mast Cell Degranulation by Disodium Cromoglycate Attenuates the Development of Hypoxic Pulmonary Hypertension in Rats Exposed to Chronic Hypoxia

(2008) Alena Baňasová et al.   RESPIRATION