Visualization of distinct substrate-recruitment pathways in the yeast exosome by EM

Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

(2013) Debora Lika Makino et al.   NATURE

The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro

(2013) Karolina Drążkowska et al.   NUCLEIC ACIDS RESEARCH

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Exo- and Endoribonucleolytic Activities of Yeast Cytoplasmic and Nuclear RNA Exosomes Are Dependent on the Noncatalytic Core and Central Channel

(2012) Elizabeth V. Wasmuth et al.   MOLECULAR CELL

Transcriptome-wide Analysis of Exosome Targets

(2012) Claudia Schneider et al.   MOLECULAR CELL

Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease

(2012) G. Lee et al.   SCIENCE

The RNA Helicase Mtr4p Modulates Polyadenylation in the TRAMP Complex

(2011) Huijue Jia et al.   CELL

tRNAs Marked with CCACCA Are Targeted for Degradation

(2011) J. E. Wilusz et al.   SCIENCE

RNA channelling by the eukaryotic exosome

(2010) Hélène Malet et al.   EMBO REPORTS

The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation

(2009) Fabien Bonneau et al.   CELL

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

(2009) Claudia Schneider et al.   NUCLEIC ACIDS RESEARCH

Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the RNase II Nuclease Family

(2008) Esben Lorentzen et al.   MOLECULAR CELL

Endonucleolytic RNA cleavage by a eukaryotic exosome

(2008) Alice Lebreton et al.   NATURE

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities

(2008) Daneen Schaeffer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY