Induced pluripotent stem cell–derived cardiomyocytes in studies of inherited arrhythmias

Genetics of ion-channel disorders

(2012) Marina Cerrone et al.   CURRENT OPINION IN CARDIOLOGY

Genetic Testing of Inherited Arrhythmias

(2012) Carlo Napolitano   PEDIATRIC CARDIOLOGY

Repolarization gradients in the intact heart: Transmural or apico-basal?

(2012) Michiel J. Janse et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

(2011) Frank Soldner et al.   CELL

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

(2011) Guang-Hui Liu et al.   Cell Stem Cell

In vitro Modeling of Ryanodine Receptor 2 Dysfunction Using Human Induced Pluripotent Stem Cells

(2011) Azra Fatima et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cardiomyocytes Obtained From Induced Pluripotent Stem Cells With Long-QT Syndrome 3 Recapitulate Typical Disease-Specific Features In Vitro

(2011) Daniela Malan et al.   CIRCULATION RESEARCH

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

(2011) A. L. Lahti et al.   Disease Models & Mechanisms

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

(2011) Christian B. Jung et al.   EMBO Molecular Medicine

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

(2011) Elena Matsa et al.   EUROPEAN HEART JOURNAL

Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure

(2011) Mihaela Gherghiceanu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation

(2011) Atara Novak et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived from transgenic LQT1 and LQT2 rabbits

(2011) Gong-Xin Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

(2011) Masayuki Yazawa et al.   NATURE

Modelling the long QT syndrome with induced pluripotent stem cells

(2011) Ilanit Itzhaki et al.   NATURE

Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development

(2011) Richard P. Davis et al.   TRENDS IN MOLECULAR MEDICINE

Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Inhibits Catecholaminergic Polymorphic Ventricular Tachycardia in a RyR2R2474S/+ Knock-In Mouse Model

(2010) Shigeki Kobayashi et al.   CIRCULATION JOURNAL

Neuregulin/ErbB Signaling Regulates Cardiac Subtype Specification in Differentiating Human Embryonic Stem Cells

(2010) Wei-Zhong Zhu et al.   CIRCULATION RESEARCH

Polymorphisms in the NOS1APGene Modulate QT Interval Duration and Risk of Arrhythmias in the Long QT Syndrome

(2010) Marta Tomás et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

(2010) Alessandra Moretti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells

(2009) Limor Zwi et al.   CIRCULATION

Developmental Basis for Electrophysiological Heterogeneity in the Ventricular and Outflow Tract Myocardium As a Substrate for Life-Threatening Ventricular Arrhythmias

(2009) Bastiaan J.D. Boukens et al.   CIRCULATION RESEARCH

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Unexpected Structural and Functional Consequences of the R33Q Homozygous Mutation in Cardiac Calsequestrin

(2008) Nicoletta Rizzi et al.   CIRCULATION RESEARCH

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE