期刊
ARCHIV DER PHARMAZIE
卷 348, 期 3, 页码 155-178出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ardp.201400340
关键词
Anthelmintic; Anticancer; Antitubercular; Benzothiazoles; Mycobacterium tuberculosis; Thioformanilides
资金
- Department of Sciences and Technology (DST) [SR/FT/CS-59/2011]
Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five-membered thiazole ring. This moiety has attracted considerable attention because of its wide range of pharmacological activities such as antitubercular, antimicrobial, antimalarial, anticonvulsant, anthelmintic, analgesic, anti-inflammatory, antidiabetic, antitumor activity, etc. In the last few years, some novel benzothiazoles have been developed with varied biological activities. To access this scaffold in high yield and to introduce diversity, a variety of new synthetic methods have been invented. In this review, we highlight the development of novel benzothiazoles for various biological activities along with the best synthetic protocols for their synthesis.
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