Bridging the efficacy–effectiveness gap: a regulator's perspective on addressing variability of drug response

The ‘Wise List’- A Comprehensive Concept to Select, Communicate and Achieve Adherence to Recommendations of Essential Drugs in Ambulatory Care in Stockholm

(2011) Lars L. Gustafsson et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

An accelerated pathway for targeted cancer therapies

(2011) Mark McClellan et al.   NATURE REVIEWS DRUG DISCOVERY

Pragmatic Trials — Guides to Better Patient Care?

(2011) James H. Ware et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Reg

(2010) Saedis Saevarsdottir et al.   ARTHRITIS AND RHEUMATISM

Body mass index and clinical response to infliximab in rheumatoid arthritis

(2010) Ruth Klaasen et al.   ARTHRITIS AND RHEUMATISM

Clinical Pharmacology in Research, Teaching and Health Care

(2010) Michael Orme et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Fruit juice inhibition of uptake transport: a new type of food-drug interaction

(2010) David G. Bailey   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Assessing the Clinical Utility of Diagnostics Used in Drug Therapy

(2010) J Woodcock   CLINICAL PHARMACOLOGY & THERAPEUTICS

Enrichment of Clinical Study Populations

(2010) R Temple   CLINICAL PHARMACOLOGY & THERAPEUTICS

Understanding Forgiveness: Minding and Mining the Gaps Between Pharmacokinetics and Therapeutics

(2010) L G Osterberg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Public Pharmacovigilance Communication

(2010) Priya Bahri   DRUG SAFETY

Relative effectiveness assessment of listed drugs (REAL): A new method for an early comparison of the effectiveness of approved health technologies

(2010) Bruno Falissard et al.   INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE

Effect of Concomitant CYP2D6 Inhibitor Use and Tamoxifen Adherence on Breast Cancer Recurrence in Early-Stage Breast Cancer

(2010) Vincent O. Dezentjé et al.   JOURNAL OF CLINICAL ONCOLOGY

The Long and Winding Road to Warfarin Pharmacogenetic Testing**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

(2010) Geoffrey S. Ginsburg et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Self-titration for treatment of uncomplicated hypertension

(2010) Gbenga Ogedegbe   LANCET

Mobile phones to improve HIV treatment adherence

(2010) Benjamin H Chi et al.   LANCET

Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial

(2010) Richard T Lester et al.   LANCET

EBM, HTA, and CER: Clearing the Confusion

(2010) BRYAN R. LUCE et al.   MILBANK QUARTERLY

2009 FDA drug approvals

(2010) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Personalized medicine in oncology: the future is now

(2010) Richard L. Schilsky   NATURE REVIEWS DRUG DISCOVERY

New drug approval success rate in Europe in 2009

(2010) Hans-Georg Eichler et al.   NATURE REVIEWS DRUG DISCOVERY

Integrating molecular diagnostics into anticancer drug discovery

(2010) István Peták et al.   NATURE REVIEWS DRUG DISCOVERY

Accelerating the Use of Electronic Health Records in Physician Practices

(2010) Steven Shea et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thinking Outside the Pillbox — Medication Adherence as a Priority for Health Care Reform

(2010) David M. Cutler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenetics of Warfarin

(2009) Farhad Kamali et al.   Annual Review of Medicine

Proposals for model-based paediatric medicinal development within the current European Union regulatory framework

(2009) Efthymios Manolis et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers

(2009) K. E. Thorpe et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Pharmacogenomics: a new paradigm to personalize treatments in nephrology patients

(2009) G. Zaza et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

SFINX—a drug-drug interaction database designed for clinical decision support systems

(2009) Ylva Böttiger et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status

(2009) Gabriele Stocco et al.   Expert Opinion On Drug Safety

Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin

(2009) David A Flockhart et al.   GENETICS IN MEDICINE

Analysis of Drug Interactions Involving Fruit Beverages and Organic Anion-Transporting Polypeptides

(2009) David J. Greenblatt   JOURNAL OF CLINICAL PHARMACOLOGY

How to reduce prescribing errors

(2009) The Lancet   LANCET

Adjustment of dosing of antimicrobial agents for bodyweight in adults

(2009) Matthew E Falagas et al.   LANCET

Rethinking therapeutic cancer vaccines

(2009)   NATURE REVIEWS DRUG DISCOVERY

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Comparison of Cost Effectiveness Using Data from Randomized Trials or Actual Clinical Practice: Selective Cox-2 Inhibitors as an Example

(2009) Tjeerd-Pieter van Staa et al.   PLOS MEDICINE

Guidance for off-label use of drugs

(2008) The Lancet Neurology   LANCET NEUROLOGY

Pharmacogenetics in drug discovery and development: a translational perspective

(2008) Allen D. Roses   NATURE REVIEWS DRUG DISCOVERY

Balancing early market access to new drugs with the need for benefit/risk data: a mounting dilemma

(2008) Hans-Georg Eichler et al.   NATURE REVIEWS DRUG DISCOVERY

More on Subgroup Analyses in Clinical Trials

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study

(2008) Louise A. Donnelly et al.   Pharmacogenetics and Genomics

Off-label drug use among hospitalised children: identifying areas with the highest need for research

(2008) Linda Hsien et al.   PHARMACY WORLD & SCIENCE

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

(2008) Irving Kirsch et al.   PLOS MEDICINE