标题
Molecular analysis of circulating tumour cells—biology and biomarkers
作者
关键词
-
出版物
Nature Reviews Clinical Oncology
Volume 11, Issue 3, Pages 129-144
出版商
Springer Nature
发表日期
2014-01-21
DOI
10.1038/nrclinonc.2013.253
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- (2014) Meenakshi Upreti et al. Translational Oncology
- Mutational Analysis of Circulating Tumor Cells Using a Novel Microfluidic Collection Device and qPCR Assay
- (2014) Wael Harb et al. Translational Oncology
- Circulating tumor cells in HER2-positive metastatic breast cancer patients: a valuable prognostic and predictive biomarker
- (2013) Yi Liu et al. BMC CANCER
- Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
- (2013) D J E Peeters et al. BRITISH JOURNAL OF CANCER
- Tumor Dissemination: An EMT Affair
- (2013) Jean Paul Thiery et al. CANCER CELL
- Circulating tumor cells as therapy-related biomarkers in cancer patients
- (2013) Tobias M. Gorges et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs
- (2013) Francesco Fabbri et al. CANCER LETTERS
- Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
- (2013) E. Heitzer et al. CANCER RESEARCH
- Cisplatin influences acquisition of resistance to molecular-targeted agents through epithelial-mesenchymal transition-like changes
- (2013) Maki Kurokawa et al. CANCER SCIENCE
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance
- (2013) D Gonzalez de Castro et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Detection of Circulating Tumor Cells Harboring a Unique ALK Rearrangement in ALK-Positive Non–Small-Cell Lung Cancer
- (2013) Emma Pailler et al. JOURNAL OF CLINICAL ONCOLOGY
- Breast Cancer Metastasis Suppressor-1 Promoter Methylation in Primary Breast Tumors and Corresponding Circulating Tumor Cells
- (2013) Maria Chimonidou et al. MOLECULAR CANCER RESEARCH
- Analysing the mutational status of PIK3CA in circulating tumor cells from metastatic breast cancer patients
- (2013) Helen Schneck et al. Molecular Oncology
- Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
- (2013) Muhammed Murtaza et al. NATURE
- Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
- (2013) Irène Baccelli et al. NATURE BIOTECHNOLOGY
- Liquid biopsy: monitoring cancer-genetics in the blood
- (2013) Emily Crowley et al. Nature Reviews Clinical Oncology
- Circulating tumour cells and cell-free DNA as tools for managing breast cancer
- (2013) Leticia De Mattos-Arruda et al. Nature Reviews Clinical Oncology
- Circulating Tumor DNA to Monitor Metastatic Breast Cancer
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
- (2013) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
- (2013) Sarah-Jane Dawson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Single-cell paired-end genome sequencing reveals structural variation per cell cycle
- (2013) Thierry Voet et al. NUCLEIC ACIDS RESEARCH
- SNAI1-Mediated Epithelial-Mesenchymal Transition Confers Chemoresistance and Cellular Plasticity by Regulating Genes Involved in Cell Death and Stem Cell Maintenance
- (2013) Soyoung Lim et al. PLoS One
- Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
- (2013) X. Ni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer
- (2013) Chun-Liang Chen et al. PROSTATE
- Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
- (2013) M. Yu et al. SCIENCE
- Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells
- (2013) E. Ozkumur et al. Science Translational Medicine
- The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis
- (2013) L. Zhang et al. Science Translational Medicine
- ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma
- (2012) M. Ilie et al. ANNALS OF ONCOLOGY
- Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor
- (2012) T. J. N. Hiltermann et al. ANNALS OF ONCOLOGY
- Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials
- (2012) François-Clément Bidard et al. CANCER AND METASTASIS REVIEWS
- Intratumor Heterogeneity: Evolution through Space and Time
- (2012) C. Swanton CANCER RESEARCH
- The Genetic Basis for Cancer Treatment Decisions
- (2012) Janet E. Dancey et al. CELL
- Evaluation of Circulating Tumor Cells and Circulating Tumor DNA in Non-Small Cell Lung Cancer: Association with Clinical Endpoints in a Phase II Clinical Trial of Pertuzumab and Erlotinib
- (2012) E. A. Punnoose et al. CLINICAL CANCER RESEARCH
- An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
- (2012) L. A. Byers et al. CLINICAL CANCER RESEARCH
- Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer
- (2012) C. Gasch et al. CLINICAL CHEMISTRY
- Circulating Tumor Cells: Liquid Biopsy of Cancer
- (2012) C. Alix-Panabieres et al. CLINICAL CHEMISTRY
- Tissue-Based Approaches to Study Pharmacodynamic Endpoints in Early Phase Oncology Clinical Trials
- (2012) Joo Ern Ang et al. CURRENT DRUG TARGETS
- Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer
- (2012) Jian-Mei Hou et al. JOURNAL OF CLINICAL ONCOLOGY
- Circulating Tumor Cells As Prognostic Markers in Neuroendocrine Tumors
- (2012) Mohid S. Khan et al. JOURNAL OF CLINICAL ONCOLOGY
- Biomarker Utility of Circulating Tumor Cells in Metastatic Cutaneous Melanoma
- (2012) Leila Khoja et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Prognostic Impact of Circulating Tumor Cells in Patients with Small Cell Lung Cancer
- (2012) Tateaki Naito et al. Journal of Thoracic Oncology
- Considerations in the development of circulating tumor cell technology for clinical use
- (2012) David R Parkinson et al. Journal of Translational Medicine
- Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
- (2012) D Ross Camidge et al. LANCET ONCOLOGY
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
- (2012) Daniel Ramsköld et al. NATURE BIOTECHNOLOGY
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors
- (2012) Edward H Cho et al. PHYSICAL BIOLOGY
- Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers
- (2012) Dena Marrinucci et al. PHYSICAL BIOLOGY
- Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines
- (2012) Ashley A. Powell et al. PLoS One
- Multiparameter Analysis, including EMT Markers, on Negatively Enriched Blood Samples from Patients with Squamous Cell Carcinoma of the Head and Neck
- (2012) Priya Balasubramanian et al. PLoS One
- mRNA-Seq of Single Prostate Cancer Circulating Tumor Cells Reveals Recapitulation of Gene Expression and Pathways Found in Prostate Cancer
- (2012) Gordon M. Cann et al. PLoS One
- Whole-Genome Sequencing and Cancer Therapy: Is Too Much Ever Enough?: Figure 1.
- (2012) Levi A. Garraway et al. Cancer Discovery
- Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer
- (2011) Jian-Mei Hou et al. AMERICAN JOURNAL OF PATHOLOGY
- Complications of CT-Guided Percutaneous Needle Biopsy of the Chest: Prevention and Management
- (2011) Carol C. Wu et al. AMERICAN JOURNAL OF ROENTGENOLOGY
- Immunohistochemistry to identify EGFR mutations or ALK rearrangements in patients with lung adenocarcinoma
- (2011) P. Hofman et al. ANNALS OF ONCOLOGY
- Twist1 Is an Independent Prognostic Factor of Esophageal Squamous Cell Carcinoma and Associated with Its Epithelial–Mesenchymal Transition
- (2011) Keun-Woo Lee et al. ANNALS OF SURGICAL ONCOLOGY
- Detection of circulating tumour cells with a hybrid (epithelial/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer
- (2011) A Lecharpentier et al. BRITISH JOURNAL OF CANCER
- A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer
- (2011) Joaquim Calbo et al. CANCER CELL
- Circulating tumor cells as pharmacodynamic biomarker in early clinical oncological trials
- (2011) Lot A. Devriese et al. CANCER TREATMENT REVIEWS
- Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas
- (2011) K. Taniguchi et al. CLINICAL CANCER RESEARCH
- Circulating tumor cells: approaches to isolation and characterization
- (2011) Min Yu et al. JOURNAL OF CELL BIOLOGY
- Clinical Significance of Circulating Tumor Cells, Including Cancer Stem-Like Cells, in Peripheral Blood for Recurrence and Prognosis in Patients With Dukes' Stage B and C Colorectal Cancer
- (2011) Hisae Iinuma et al. JOURNAL OF CLINICAL ONCOLOGY
- Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer
- (2011) Matthew G. Krebs et al. JOURNAL OF CLINICAL ONCOLOGY
- Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches
- (2011) Matthew G. Krebs et al. Journal of Thoracic Oncology
- Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)
- (2011) Hui-Sung Moon et al. LAB ON A CHIP
- Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
- (2011) Caicun Zhou et al. LANCET ONCOLOGY
- Circulating Tumor Cells from Patients with Advanced Prostate and Breast Cancer Display Both Epithelial and Mesenchymal Markers
- (2011) A. J. Armstrong et al. MOLECULAR CANCER RESEARCH
- Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
- (2011) J. M. Stewart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia
- (2010) C. M. Bateman et al. BLOOD
- Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer
- (2010) L M Flores et al. BRITISH JOURNAL OF CANCER
- Eradication of EGFR-positive circulating tumor cells and objective tumor response with lapatinib and capecitabine
- (2010) Zhian Liu et al. CANCER BIOLOGY & THERAPY
- M30 Neoepitope Expression in Epithelial Cancer: Quantification of Apoptosis in Circulating Tumor Cells by CellSearch Analysis
- (2010) E. Rossi et al. CLINICAL CANCER RESEARCH
- Detection and HER2 Expression of Circulating Tumor Cells: Prospective Monitoring in Breast Cancer Patients Treated in the Neoadjuvant GeparQuattro Trial
- (2010) S. Riethdorf et al. CLINICAL CANCER RESEARCH
- Monitoring Drug-Induced H2AX as a Pharmacodynamic Biomarker in Individual Circulating Tumor Cells
- (2010) L. H. Wang et al. CLINICAL CANCER RESEARCH
- Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker
- (2010) V. Hofman et al. CLINICAL CANCER RESEARCH
- Detection of Androgen Receptor Mutations in Circulating Tumor Cells in Castration-Resistant Prostate Cancer
- (2010) Y. Jiang et al. CLINICAL CHEMISTRY
- External quality assurance of circulating tumor cell enumeration using the CellSearch® system: A feasibility study
- (2010) Jaco Kraan et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
- (2010) Wendy De Roock et al. LANCET ONCOLOGY
- Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
- (2010) Qicheng Zhao et al. Molecular Cancer
- Genetic variegation of clonal architecture and propagating cells in leukaemia
- (2010) Kristina Anderson et al. NATURE
- Genome remodelling in a basal-like breast cancer metastasis and xenograft
- (2010) Li Ding et al. NATURE
- Distant metastasis occurs late during the genetic evolution of pancreatic cancer
- (2010) Shinichi Yachida et al. NATURE
- Personalized medicine in oncology: the future is now
- (2010) Richard L. Schilsky NATURE REVIEWS DRUG DISCOVERY
- Malignant cells facilitate lung metastasis by bringing their own soil
- (2010) D. G. Duda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
- (2010) S. L. Stott et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays
- (2010) A.-E. Saliba et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer
- (2010) S. L. Stott et al. Science Translational Medicine
- Circulating tumour cells: their utility in cancer management and predicting outcomes
- (2010) Matthew G. Krebs et al. Therapeutic Advances in Medical Oncology
- Circulating tumor cells and bone metastases as detected by FDG-PET/CT in patients with metastatic breast cancer
- (2009) U. De Giorgi et al. ANNALS OF ONCOLOGY
- Correlation of HER2 status between primary tumors and corresponding circulating tumor cells in advanced breast cancer patients
- (2009) Marta Pestrin et al. BREAST CANCER RESEARCH AND TREATMENT
- Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer
- (2009) G. Attard et al. CANCER RESEARCH
- Epithelial-Mesenchymal Transition and Cell Cooperativity in Metastasis
- (2009) T. Tsuji et al. CANCER RESEARCH
- Tumor Self-Seeding by Circulating Cancer Cells
- (2009) Mi-Young Kim et al. CELL
- Fluorescence In situ Hybridization Analysis of Circulating Tumor Cells in Metastatic Prostate Cancer
- (2009) M. A. Leversha et al. CLINICAL CANCER RESEARCH
- Characterization of circulating tumor cells by fluorescence in situ hybridization
- (2009) Joost F. Swennenhuis et al. CYTOMETRY PART A
- Isolation of rare cells from cell mixtures by dielectrophoresis
- (2009) Peter R. C. Gascoyne et al. ELECTROPHORESIS
- Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients
- (2009) Janice Lu et al. INTERNATIONAL JOURNAL OF CANCER
- EMT: When epithelial cells decide to become mesenchymal-like cells
- (2009) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Personalized Cancer Therapy With Selective Kinase Inhibitors: An Emerging Paradigm in Medical Oncology
- (2009) Ultan McDermott et al. JOURNAL OF CLINICAL ONCOLOGY
- Cytokeratin-19 mRNA-Positive Circulating Tumor Cells After Adjuvant Chemotherapy in Patients With Early Breast Cancer
- (2009) Nikolaos Xenidis et al. JOURNAL OF CLINICAL ONCOLOGY
- Circulating tumour tissue fragments in patients with pulmonary metastasis of clear cell renal cell carcinoma
- (2009) Gursah Kats-Ugurlu et al. JOURNAL OF PATHOLOGY
- mRNA-Seq whole-transcriptome analysis of a single cell
- (2009) Fuchou Tang et al. NATURE METHODS
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
- (2009) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device
- (2009) A. H. Talasaz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
- (2009) K. S. Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
- (2009) C. Gjerdrum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinical Significance of Circulating Tumor Cells in Blood from Patients with Gastrointestinal Cancers
- (2008) Kunihiko Hiraiwa et al. ANNALS OF SURGICAL ONCOLOGY
- Differential gene expression profiles are dependent upon method of peripheral blood collection and RNA isolation
- (2008) Adam L Asare et al. BMC GENOMICS
- Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
- (2008) T. Tsuji et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Prognostic Significance of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transition Protein Expression in Non-Small Cell Lung Cancer
- (2008) A. Soltermann et al. CLINICAL CANCER RESEARCH
- Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer
- (2008) J. S. de Bono et al. CLINICAL CANCER RESEARCH
- Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer
- (2008) Steven J. Cohen et al. JOURNAL OF CLINICAL ONCOLOGY
- Detection of Mutations inEGFRin Circulating Lung-Cancer Cells
- (2008) Shyamala Maheswaran et al. NEW ENGLAND JOURNAL OF MEDICINE
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