Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes

Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain

(2017) Blue B Lake et al.   NATURE BIOTECHNOLOGY

Massively parallel single-nucleus RNA-seq with DroNc-seq

(2017) Naomi Habib et al.   NATURE METHODS

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

(2016) Gioele La Manno et al.   CELL

A comprehensive transcriptional map of primate brain development

(2016) Trygve E. Bakken et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

(2016) B. B. Lake et al.   SCIENCE

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome

(2016) Lynn Marie Butler et al.   Cell Systems

Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression

(2015) Lucia L Peixoto et al.   BMC GENOMICS

Epigenetic stability in the adult mouse cortex under conditions of pharmacologically induced histone acetylation

(2015) Jamie Benoit et al.   Brain Structure & Function

High-performance probes for light and electron microscopy

(2015) Sarada Viswanathan et al.   NATURE METHODS

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Canonical genetic signatures of the adult human brain

(2015) Michael Hawrylycz et al.   NATURE NEUROSCIENCE

A survey of human brain transcriptome diversity at the single cell level

(2015) Spyros Darmanis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

(2015) Ovidiu D. Iancu et al.   Frontiers in Genetics

A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells

(2014) Jennifer Zenker et al.   GLIA

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Radial glia require PDGFD–PDGFRβ signalling in human but not mouse neocortex

(2014) Jan H. Lui et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease

(2014) Paul D. Wes et al.   PLoS One

COMPARTMENTS: unification and visualization of protein subcellular localization evidence

(2014) J. X. Binder et al.   Database-The Journal of Biological Databases and Curation

Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness

(2014) Katarzyna Bozek et al.   PLOS BIOLOGY

DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data

(2013) Ting Gong et al.   BIOINFORMATICS

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study

(2013) Masaaki Hokama et al.   CEREBRAL CORTEX

Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions

(2013) Anna V. Molofsky et al.   GLIA

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

A novel genetic locus modulates infarct volume independently of the extent of collateral circulation

(2013) Pei-Lun Chu et al.   PHYSIOLOGICAL GENOMICS

Whole Brain and Brain Regional Coexpression Network Interactions Associated with Predisposition to Alcohol Consumption

(2013) Lauren A. Vanderlinden et al.   PLoS One

Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

(2013) J. Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Self-Directed Method for Cell-Type Identification and Separation of Gene Expression Microarrays

(2013) Neta S. Zuckerman et al.   PLoS Computational Biology

Cell population-specific expression analysis of human cerebellum

(2012) Alexandre Kuhn et al.   BMC GENOMICS

Network methods for describing sample relationships in genomic datasets: application to Huntington’s disease

(2012) Michael C Oldham et al.   BMC Systems Biology

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

(2012) David H Cribbs et al.   Journal of Neuroinflammation

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

(2012) Dena G. Hernandez et al.   NEUROBIOLOGY OF DISEASE

Molecular Microcircuitry Underlies Functional Specification in a Basal Ganglia Circuit Dedicated to Vocal Learning

(2012) Austin T. Hilliard et al.   NEURON

Transcriptional Architecture of the Primate Neocortex

(2012) Amy Bernard et al.   NEURON

Dysregulation of Gene Expression in a Lysosomal Storage Disease Varies between Brain Regions Implicating Unexpected Mechanisms of Neuropathology

(2012) Michael K. Parente et al.   PLoS One

Genetic Dissection of Acute Ethanol Responsive Gene Networks in Prefrontal Cortex: Functional and Mechanistic Implications

(2012) Aaron R. Wolen et al.   PLoS One

The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells

(2012) Gesine Paul et al.   PLoS One

Multiple Preconditioning Paradigms Converge on Interferon Regulatory Factor-Dependent Signaling to Promote Tolerance to Ischemic Brain Injury

(2011) S. L. Stevens et al.   JOURNAL OF NEUROSCIENCE

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain

(2011) Alexandre Kuhn et al.   NATURE METHODS

Quantitative Expression Profile of Distinct Functional Regions in the Adult Mouse Brain

(2011) Takeya Kasukawa et al.   PLoS One

Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains

(2011) Cristina S. Benton et al.   PSYCHOPHARMACOLOGY

Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF-04447943

(2010) Robin J. Kleiman et al.   Alzheimers & Dementia

Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice

(2010) S. K. Segall et al.   GENES BRAIN AND BEHAVIOR

Cell type–specific gene expression differences in complex tissues

(2010) Shai S Shen-Orr et al.   NATURE METHODS

Amygdala Transcriptome and Cellular Mechanisms Underlying Stress-Enhanced Fear Learning in a Rat Model of Posttraumatic Stress Disorder

(2010) Igor Ponomarev et al.   NEUROPSYCHOPHARMACOLOGY

Phenopedia and Genopedia: disease-centered and gene-centered views of the evolving knowledge of human genetic associations

(2009) W. Yu et al.   BIOINFORMATICS

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus

(2009) Alexander R. Abbas et al.   PLoS One

Transcriptional neoteny in the human brain

(2009) M. Somel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Functional organization of the transcriptome in human brain

(2008) Michael C Oldham et al.   NATURE NEUROSCIENCE

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric Interpretation of Gene Coexpression Network Analysis

(2008) Steve Horvath et al.   PLoS Computational Biology