Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

Abnormal Interactions between Perifollicular Mast Cells and CD8+ T-Cells May Contribute to the Pathogenesis of Alopecia Areata

(2014) Marta Bertolini et al.   PLoS One

Janus kinase inhibitors in autoimmune diseases

(2013) John J O'Shea et al.   ANNALS OF THE RHEUMATIC DISEASES

Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

(2013) J Adam Best et al.   NATURE IMMUNOLOGY

Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis

(2012) Naresh Punwani et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Molecular definition of the identity and activation of natural killer cells

(2012) Natalie A Bezman et al.   NATURE IMMUNOLOGY

Alopecia Areata

(2012) Amos Gilhar et al.   NEW ENGLAND JOURNAL OF MEDICINE

JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis

(2012) Claire Harrison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

(2011) Kamran Ghoreschi et al.   JOURNAL OF IMMUNOLOGY

Companies hope for kinase inhibitor JAKpot

(2011) Elie Dolgin   NATURE REVIEWS DRUG DISCOVERY

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

(2010) A. Quintas-Cardama et al.   BLOOD

Contribution of Astrocyte-Derived IL-15 to CD8 T Cell Effector Functions in Multiple Sclerosis

(2010) P. Saikali et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

(2010) Lynn Petukhova et al.   NATURE

Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis

(2010) Srdan Verstovsek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack

(2007) Taisuke Ito et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY