The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog−driven medulloblastoma

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

(2014) Marcel Kool et al.   CANCER CELL

Novel nonsenseGNASmutation in a 14-month-old boy with plate-like osteoma cutis and medulloblastoma

(2014) Ji Young Huh et al.   JOURNAL OF DERMATOLOGY

Olig1 Function Is Required to Repress Dlx1/2 and Interneuron Production in Mammalian Brain

(2014) John C. Silbereis et al.   NEURON

The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling

(2013) Saikat Mukhopadhyay et al.   CELL

Interaction of PACAP with Sonic hedgehog reveals complex regulation of the Hedgehog pathway by PKA

(2013) Pawel Niewiadomski et al.   CELLULAR SIGNALLING

Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction

(2013) Yoko Inès Nozawa et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

(2013) Jean B Regard et al.   NATURE MEDICINE

Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem

(2012) Daniel Grammel et al.   ACTA NEUROPATHOLOGICA

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

(2012) Paul A. Northcott et al.   NATURE

The clinical implications of medulloblastoma subgroups

(2012) Paul A. Northcott et al.   Nature Reviews Neurology

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

(2011) Paul A. Northcott et al.   ACTA NEUROPATHOLOGICA

Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

(2011) Paul A. Northcott et al.   ACTA NEUROPATHOLOGICA

Molecular subgroups of medulloblastoma: the current consensus

(2011) Michael D. Taylor et al.   ACTA NEUROPATHOLOGICA

A procedure to statistically evaluate agreement of differential expression for cross-species genomics

(2011) Stan Pounds et al.   BIOINFORMATICS

CXCR4 Activation Defines a New Subgroup of Sonic Hedgehog-Driven Medulloblastoma

(2011) R. Sengupta et al.   CANCER RESEARCH

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube

(2011) M. Tuson et al.   DEVELOPMENT

Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip

(2011) R. Machold et al.   GENE EXPRESSION PATTERNS

Adult Medulloblastoma Comprises Three Major Molecular Variants

(2011) Marc Remke et al.   JOURNAL OF CLINICAL ONCOLOGY

FSTL5Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma

(2011) Marc Remke et al.   JOURNAL OF CLINICAL ONCOLOGY

Wnt/ -catenin signaling is differentially regulated by G  proteins and contributes to fibrous dysplasia

(2011) J. B. Regard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treating brain tumors with PDE4 inhibitors

(2011) Rajarshi Sengupta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Misregulation of Scm3p/HJURP Causes Chromosome Instability in Saccharomyces cerevisiae and Human Cells

(2011) Prashant K. Mishra et al.   PLoS Genetics

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance

(2010) Gerrit J. P. Dijkgraaf et al.   CANCER RESEARCH

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

(2010) Yoon-Jae Cho et al.   JOURNAL OF CLINICAL ONCOLOGY

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres

(2009) Elaine M. Dunleavy et al.   CELL

Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

(2009) R. L. Yauch et al.   SCIENCE

The Origins of Medulloblastoma Subtypes

(2008) Richard J. Gilbertson et al.   Annual Review of Pathology-Mechanisms of Disease

Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma

(2008) Ulrich Schüller et al.   CANCER CELL

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

(2008) Yong Pan et al.   DEVELOPMENTAL BIOLOGY

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

(2008) A. J. Vilella et al.   GENOME RESEARCH