Rapid host immune response and viral dynamics in herpes simplex virus-2 infection

cis-Urocanic Acid Initiates Gene Transcription in Primary Human Keratinocytes

(2014) K. Kaneko et al.   JOURNAL OF IMMUNOLOGY

Maintenance of T Cell Function in the Face of Chronic Antigen Stimulation and Repeated Reactivation for a Latent Virus Infection

(2012) L. K. Mackay et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF- B

(2012) V. Leoni et al.   JOURNAL OF VIROLOGY

An Effector Phenotype of CD8+ T Cells at the Junction Epithelium during Clinical Quiescence of Herpes Simplex Virus 2 Infection

(2012) T. Peng et al.   JOURNAL OF VIROLOGY

Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials

(2012) Christine Johnston et al.   LANCET

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection

(2011) Elizabeth Tronstein   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy

(2011) J. T. Schiffer et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

(2011) Vanessa Sancho-Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

(2011) Yiqi Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Male Circumcision and Herpes Simplex Virus Type 2 Infection in Female Partners: A Randomized Trial in Rakai, Uganda

(2011) A. A. R. Tobian et al.   JOURNAL OF INFECTIOUS DISEASES

The Kinetics of Mucosal Herpes Simplex Virus–2 Infection in Humans: Evidence for Rapid Viral-Host Interactions

(2011) Joshua T. Schiffer et al.   JOURNAL OF INFECTIOUS DISEASES

Immunization with a Vaccine Combining Herpes Simplex Virus 2 (HSV-2) Glycoprotein C (gC) and gD Subunits Improves the Protection of Dorsal Root Ganglia in Mice and Reduces the Frequency of Recurrent Vaginal Shedding of HSV-2 DNA in Guinea Pigs Compared to Immunization with gD Alone

(2011) S. Awasthi et al.   JOURNAL OF VIROLOGY

Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection

(2011) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Factors Associated With Herpes Simplex Virus Type 2 Incidence in a Cohort of Human Immunodeficiency Virus Type 1-Seronegative Kenyan Men and Women Reporting High-Risk Sexual Behavior

(2011) Haile Selassie Okuku et al.   SEXUALLY TRANSMITTED DISEASES

Rapid recruitment and activation of CD8+ T cells after herpes simplex virus type 1 skin infection

(2010) Angus T Stock et al.   IMMUNOLOGY AND CELL BIOLOGY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Herpes Simplex Virus Infects Skin    T Cells before Langerhans Cells and Impedes Migration of Infected Langerhans Cells by Inducing Apoptosis and Blocking E-Cadherin Downregulation

(2010) F. K. Puttur et al.   JOURNAL OF IMMUNOLOGY

Overlapping Reactivations of Herpes Simplex Virus Type 2 in the Genital and Perianal Mucosa

(2010) Sunitha Tata et al.   JOURNAL OF INFECTIOUS DISEASES

Persistent Genital Herpes Simplex Virus-2 Shedding Years Following the First Clinical Episode

(2010) Warren Phipps et al.   JOURNAL OF INFECTIOUS DISEASES

Spread of Herpes Simplex Virus to the Spinal Cord Is Independent of Spread to Dorsal Root Ganglia

(2010) M. Ohashi et al.   JOURNAL OF VIROLOGY

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing

(2010) X. Jiang et al.   JOURNAL OF VIROLOGY

Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes

(2010) J. T. Schiffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Painful Failure of Promising Genital Herpes Vaccine

(2010) J. Cohen   SCIENCE

Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection

(2009) Heung Kyu Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Early CD4 + T Cell Help Prevents Partial CD8 + T Cell Exhaustion and Promotes Maintenance of Herpes Simplex Virus 1 Latency

(2009) Gregory M. Frank et al.   JOURNAL OF IMMUNOLOGY

Factors Associated with the Prevalence and Incidence of Herpes Simplex Virus Type 2 Infection among Men in Rakai, Uganda

(2009) Aaron A. R. Tobian et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of HSV‐2 Serostatus on Acquisition of HIV by Young Men: Results of a Longitudinal Study in Orange Farm, South Africa

(2009) Joelle Sobngwi‐Tambekou et al.   JOURNAL OF INFECTIOUS DISEASES

Herpes Simplex Virus Type 1 Glycoprotein E Mediates Retrograde Spread from Epithelial Cells to Neurites

(2009) H. M. McGraw et al.   JOURNAL OF VIROLOGY

Mucosal Innate and Adaptive Immune Responses against Herpes Simplex Virus Type 2 in a Humanized Mouse Model

(2009) A. Kwant-Mitchell et al.   JOURNAL OF VIROLOGY

The Virological Synapse Facilitates Herpes Simplex Virus Entry into T Cells

(2009) M. Aubert et al.   JOURNAL OF VIROLOGY

Evasion of the Mucosal Innate Immune System by Herpes Simplex Virus Type 2

(2009) T. Peng et al.   JOURNAL OF VIROLOGY

Anterograde Spread of Herpes Simplex Virus Type 1 Requires Glycoprotein E and Glycoprotein I but Not Us9

(2009) H. M. McGraw et al.   JOURNAL OF VIROLOGY

Identification of Viral MicroRNAs Expressed in Human Sacral Ganglia Latently Infected with Herpes Simplex Virus 2

(2009) J. L. Umbach et al.   JOURNAL OF VIROLOGY

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

(2009) William R Heath et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Persistence of HIV-1 receptor–positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition

(2009) Jia Zhu et al.   NATURE MEDICINE

Frequent Release of Low Amounts of Herpes Simplex Virus from Neurons: Results of a Mathematical Model

(2009) J. T. Schiffer et al.   Science Translational Medicine

Herpes Simplex: Insights on Pathogenesis and Possible Vaccines

(2008) David M. Koelle et al.   Annual Review of Medicine

An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection

(2008) Katharine Looker   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

(2008) Christopher M. Snyder et al.   IMMUNITY

CD8+ T-cell attenuation of cutaneous herpes simplex virus infection reduces the average viral copy number of the ensuing latent infection

(2008) Linda M Wakim et al.   IMMUNOLOGY AND CELL BIOLOGY

Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus

(2008) Norifumi Iijima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapidly Cleared Episodes of Herpes Simplex Virus Reactivation in Immunocompetent Adults

(2008) Karen E. Mark et al.   JOURNAL OF INFECTIOUS DISEASES

Role for Plasmacytoid Dendritic Cells in the Immune Control of Recurrent Human Herpes Simplex Virus Infection

(2008) H. Donaghy et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus gE/gI and US9 Proteins Promote Transport of both Capsids and Virion Glycoproteins in Neuronal Axons

(2008) A. Snyder et al.   JOURNAL OF VIROLOGY

Chromatin control of herpes simplex virus lytic and latent infection

(2008) David M. Knipe et al.   NATURE REVIEWS MICROBIOLOGY

Genital Herpes Has Played a More Important Role than Any Other Sexually Transmitted Infection in Driving HIV Prevalence in Africa

(2008) Laith J. Abu-Raddad et al.   PLoS One

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

(2008) L. M. Wakim et al.   SCIENCE

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE

The number of herpes simplex virus-infected neurons and the number of viral genome copies per neuron correlate with the latent viral load in ganglia

(2007) Yo Hoshino et al.   VIROLOGY