Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones

(2011) Min Lu et al.   NATURE MEDICINE

A role for central nervous system PPAR-γ in the regulation of energy balance

(2011) Karen K Ryan et al.   NATURE MEDICINE

Hypothalamic Responses to Fasting Indicate Metabolic Reprogramming Away from Glycolysis Toward Lipid Oxidation

(2010) Michal M. Poplawski et al.   ENDOCRINOLOGY

Minireview: Inflammation and Obesity Pathogenesis: The Hypothalamus Heats Up

(2010) Joshua P. Thaler et al.   ENDOCRINOLOGY

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance

(2009) Lale Ozcan et al.   Cell Metabolism

Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons

(2009) Denise D. Belsham et al.   FASEB JOURNAL

Interrelationship between Liver X Receptor α, Sterol Regulatory Element-binding Protein-1c, Peroxisome Proliferator-activated Receptor γ, and Small Heterodimer Partner in the Transcriptional Regulation of Glucokinase Gene Expression in Liver

(2009) Tae-Hyun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor-γ (PPARγ) modulates hypothalamic Trh regulation in vivo

(2009) Soumaya Kouidhi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Honokiol is a potent scavenger of superoxide and peroxyl radicals

(2008) Sergey Dikalov et al.   BIOCHEMICAL PHARMACOLOGY

Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus

(2008) Xin Yu et al.   BRAIN RESEARCH

Peroxisome Proliferator-Activated Receptor-γ-Mediated Positive Energy Balance in the Rat Is Associated with Reduced Sympathetic Drive to Adipose Tissues and Thyroid Status

(2008) William T. Festuccia et al.   ENDOCRINOLOGY

Expression of Peroxisome Proliferator-Activated Receptor-γ in Key Neuronal Subsets Regulating Glucose Metabolism and Energy Homeostasis

(2008) David A. Sarruf et al.   ENDOCRINOLOGY

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

Cidea is associated with lipid droplets and insulin sensitivity in humans

(2008) V. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fuel utilization by hypothalamic neurons: roles for ROS

(2008) Tamas L. Horvath et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM