The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus–induced microRNAs

IL28B genotype and the expression of ISGs in normal liver

(2013) Zoe Raglow et al.   LIVER INTERNATIONAL

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

(2013) Ludmila Prokunina-Olsson et al.   NATURE GENETICS

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differences in microRNA detection levels are technology and sequence dependent

(2013) D. Leshkowitz et al.   RNA

Combinations of Lambda Interferon with Direct-Acting Antiviral Agents Are Highly Efficient in Suppressing Hepatitis C Virus Replication

(2012) Jacques Friborg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hepatic Cell–Type Specific Gene Expression Better Predicts HCV Treatment Outcome Than IL28B Genotype

(2012) Ian McGilvray et al.   GASTROENTEROLOGY

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

(2012) Susanna Naggie et al.   HEPATOLOGY

Human blood dendritic cell antigen 3 (BDCA3)+dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

(2012) Sachiyo Yoshio et al.   HEPATOLOGY

Interferon-lambda (IFN- ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

(2012) H. Dickensheets et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protease inhibitors for the treatment of chronic hepatitis C genotype-1 infection: the new standard of care

(2012) Brian L Pearlman   LANCET INFECTIOUS DISEASES

Deciphering the Interleukin 28B Variants That Better Predict Response to Pegylated Interferon-α and Ribavirin Therapy in HCV/HIV-1 Coinfected Patients

(2012) Montserrat de Castellarnau et al.   PLoS One

Analysis of IL28B Variants in an Egyptian Population Defines the 20 Kilobases Minimal Region Involved in Spontaneous Clearance of Hepatitis C Virus

(2012) Vincent Pedergnana et al.   PLoS One

Uridine Composition of the Poly-U/UC Tract of HCV RNA Defines Non-Self Recognition by RIG-I

(2012) Gretja Schnell et al.   PLoS Pathogens

Potential pitfalls in microRNA profiling

(2012) Pauline Chugh et al.   Wiley Interdisciplinary Reviews-RNA

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance

(2011) Julia di Iulio et al.   HEPATOLOGY

An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases

(2011) Marc G. Ghany et al.   HEPATOLOGY

Evolutionary genetic dissection of human interferons

(2011) Jérémy Manry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential microRNA regulation of HLA-C expression and its association with HIV control

(2011) Smita Kulkarni et al.   NATURE

IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties

(2010) Katrin Witte et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C

(2010) Masao Honda et al.   GASTROENTEROLOGY

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

IL28B and the Control of Hepatitis C Virus Infection

(2010) Ashwin Balagopal et al.   GASTROENTEROLOGY

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C

(2010) Thomas J. Urban et al.   HEPATOLOGY

Interferon-lambda serum levels in hepatitis C

(2010) Bettina Langhans et al.   JOURNAL OF HEPATOLOGY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A Family of microRNAs Encoded by Myosin Genes Governs Myosin Expression and Muscle Performance

(2009) Eva van Rooij et al.   DEVELOPMENTAL CELL

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Clinical implications of anti-heart autoantibodies in myocarditis and dilated cardiomyopathy

(2008) Alida L. P. Caforio et al.   AUTOIMMUNITY

Human interferon-λ3 is a potent member of the type III interferon family

(2008) C Dellgren et al.   GENES AND IMMUNITY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens