Conformational states of the kinase Lck regulate clustering in early T cell signaling

CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T Cells

(2014) N. K. Y. Wong et al.   JOURNAL OF IMMUNOLOGY

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

(2011) Eilon Sherman et al.   IMMUNITY

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

A negatively charged domain of LAT mediates its interaction with the active form of Lck

(2011) Panagiotis S. Kabouridis et al.   MOLECULAR MEMBRANE BIOLOGY

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

(2011) David J Williamson et al.   NATURE IMMUNOLOGY

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

Quantitative Photo Activated Localization Microscopy: Unraveling the Effects of Photoblinking

(2011) Paolo Annibale et al.   PLoS One

Basic residues in the T-cell receptor   cytoplasmic domain mediate membrane association and modulate signaling

(2011) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutively Active Lck Kinase in T Cells Drives Antigen Receptor Signal Transduction

(2010) Konstantina Nika et al.   IMMUNITY

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

(2010) Dylan M. Owen et al.   Journal of Biophotonics

T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering

(2010) A. Hashimoto-Tane et al.   MOLECULAR AND CELLULAR BIOLOGY

Lck and the nature of the T cell receptor trigger

(2010) Simon J. Davis et al.   TRENDS IN IMMUNOLOGY

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Modulation of immune cell signalling by the leukocyte common tyrosine phosphatase, CD45

(2009) A.E. Saunders et al.   CELLULAR SIGNALLING

Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling

(2009) Tobias Zech et al.   EMBO JOURNAL

The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells

(2009) Yoshihisa Kaizuka et al.   JOURNAL OF CELL BIOLOGY

Genetically Encoded Forster Resonance Energy Transfer Sensors for the Conformation of the Src Family Kinase Lck

(2009) W. Paster et al.   JOURNAL OF IMMUNOLOGY

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

(2009) Björn F Lillemeier et al.   NATURE IMMUNOLOGY

The Safety on the TCR Trigger

(2008) Michael S. Kuhns et al.   CELL

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

(2008) Chenqi Xu et al.   CELL

Functional Implications of Plasma Membrane Condensation for T Cell Activation

(2008) Carles Rentero et al.   PLoS One

Binding specificity of SH2 domains: Insight from free energy simulations

(2008) Wenxun Gan et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE