Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

The Failing Heart Stimulates Tumor Growth by Circulating Factors

(2018) Wouter C. Meijers et al.   CIRCULATION

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

Roseburia spp.: a marker of health?

(2017) Zohreh Tamanai-Shacoori et al.   Future Microbiology

Vitamin D receptor is a novel transcriptional regulator for Axin1

(2017) Dapeng Jin et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Association analyses based on false discovery rate implicate new loci for coronary artery disease

(2017) Christopher P Nelson et al.   NATURE GENETICS

Connecting genetic risk to disease end points through the human blood plasma proteome

(2017) Karsten Suhre et al.   Nature Communications

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

(2017) Lasse Folkersen et al.   PLoS Genetics

Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction

(2017) Ivan Rodriguez-Nunez et al.   Scientific Reports

Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L.

(2016) Sachi Tanaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

(2016) Floris Imhann et al.   GUT

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Identification of context-dependent expression quantitative trait loci in whole blood

(2016) Daria V Zhernakova et al.   NATURE GENETICS

Gut microbiota induce IGF-1 and promote bone formation and growth

(2016) Jing Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD

(2016) Wei Sun et al.   PLoS Genetics

Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health

(2016) David Ríos-Covián et al.   Frontiers in Microbiology

Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders

(2015) K. Gottlieb et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

PreQ0 Base, an Unusual Metabolite with Anti-cancer Activity from Streptomyces qinglanensis 172205

(2015) Dongbo Xu et al.   Anti-Cancer Agents in Medicinal Chemistry

Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin

(2015) Y Andersson et al.   BRITISH JOURNAL OF CANCER

TNFR2 Deficiency Acts in Concert with Gut Microbiota To Precipitate Spontaneous Sex-Biased Central Nervous System Demyelinating Autoimmune Disease

(2015) Patrick G. Miller et al.   JOURNAL OF IMMUNOLOGY

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

(2015) Duy Tin Truong et al.   NATURE METHODS

Gut colonization withmethanobrevibacter smithiiis associated with childhood weight development

(2015) Catherine A. Mbakwa et al.   Obesity

Gut mucosal microbiome across stages of colorectal carcinogenesis

(2015) Geicho Nakatsu et al.   Nature Communications

Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

(2015) Ettje F Tigchelaar et al.   BMJ Open

Antioxidant properties of HDL

(2015) Handrean Soran et al.   Frontiers in Pharmacology

Learning Bayesian Networks with thebnlearnRPackage

(2015) Marco Scutari   Journal of Statistical Software

mediation:RPackage for Causal Mediation Analysis

(2015) Dustin Tingley et al.   Journal of Statistical Software

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

(2015) Marc Schneeberger et al.   Scientific Reports

Protein Biomarkers of New-Onset Cardiovascular Disease

(2014) Xiaoyan Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Intestinal permeability – a new target for disease prevention and therapy

(2014) Stephan C Bischoff et al.   BMC GASTROENTEROLOGY

Cohort Profile: LifeLines, a three-generation cohort study and biobank

(2014) Salome Scholtens et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism

(2014) Maomeng Tong et al.   ISME Journal

The contributory role of gut microbiota in cardiovascular disease

(2014) W.H. Wilson Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction

(2014) Philip A. Kozan et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Whole-genome sequence variation, population structure and demographic history of the Dutch population

(2014) Laurent C Francioli et al.   NATURE GENETICS

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

(2014) Erika Assarsson et al.   PLoS One

Complex host genetics influence the microbiome in inflammatory bowel disease

(2014) Dan Knights et al.   Genome Medicine

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

(2013) Meian He et al.   GUT

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Clostridia: leading players in the maintenance of gut homeostasis

(2013) Loris R Lopetuso et al.   Gut Pathogens

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Axin1 Prevents Salmonella Invasiveness and Inflammatory Response in Intestinal Epithelial Cells

(2012) Yong-guo Zhang et al.   PLoS One

Expression of Human Paraoxonase 1 Decreases Superoxide Levels and Alters Bacterial Colonization in the Gut of Drosophila melanogaster

(2012) Alejandro A. Pezzulo et al.   PLoS One

Regression shrinkage and selection via the lasso: a retrospective

(2011) Robert Tibshirani   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

(2011) P. Rausch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

(2011) Roberto Berni Canani   WORLD JOURNAL OF GASTROENTEROLOGY

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

Whole-exome sequencing for finding de novo mutations in sporadic mental retardation

(2011) Peter N Robinson   GENOME BIOLOGY

The three-gene paraoxonase family: Physiologic roles, actions and regulation

(2010) Louis-Philippe Précourt et al.   ATHEROSCLEROSIS

Adecatumumab: an anti-EpCAM monoclonal antibody, from the bench to the bedside

(2010) Jean-Emmanuel Kurtz et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E knockout mice

(2010) C Zhang et al.   GENE THERAPY

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

EpCAM As a Target in Cancer Therapy

(2010) Olivier Gires et al.   JOURNAL OF CLINICAL ONCOLOGY

rtracklayer: an R package for interfacing with genome browsers

(2009) M. Lawrence et al.   BIOINFORMATICS

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

(2009) Ana Magalhães et al.   GLYCOBIOLOGY

TMEM8 – a non-globin gene entrapped in the globin web

(2009) Elena S. Philonenko et al.   NUCLEIC ACIDS RESEARCH

Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells

(2008) Susan Kenny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1

(2008) David A. Stoltz et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants of FUT2 are associated with plasma vitamin B12 levels

(2008) Aditi Hazra et al.   NATURE GENETICS